POSTOPERATIVE PAIN MANAGEMENT

This study looks at whether adding dexmedetomidine to a standard numbing medicine (ropivacaine) in a nerve block can improve pain control after hip replacement surgery. About 120 adults aged 18-80 having elective hip surgery will take part. The goal is to see if the combination d…

This study tests if a non-invasive device that gently stimulates a nerve in the ear can help reduce inflammation and pain after major spine surgery. Researchers will measure inflammatory markers and pain scores in 50 adults undergoing long-segment spinal fusion. The goal is to se…

This study compares two pain relief methods for women having laparoscopic hysterectomy: a spinal injection of morphine versus numbing medicine injected into the belly and surgical sites. The goal is to see which approach leads to better recovery, less pain, and fewer side effects…

This study tests a new pain medicine called HSK21542 for people who have hip replacement surgery. About 405 adults will receive either the new drug, morphine, or a placebo to see how well it controls pain and reduces side effects like nausea and vomiting. The goal is to find a sa…

This study looks at whether adding a TAP block (a numbing injection in the belly wall) to standard spinal morphine helps women feel better and recover faster after a planned C-section. About 150 women will take part. Researchers will measure recovery quality, pain levels, and how…

This study tests two different painkiller combinations (dezocine vs. nalbuphine, both with sufentanil) in 60 adults undergoing oral cancer surgery with flap reconstruction. The goal is to find which provides better pain control, fewer side effects like nausea, and helps the surgi…

This study compares two ways to manage pain after umbilical hernia surgery: a single-dose epidural block and an ultrasound-guided TAP block. Researchers will measure pain levels at 30 minutes and 6 hours after surgery using a simple 0-10 pain scale. The goal is to find which meth…

This study looks at 27 adults having lung surgery to find the smallest effective dose of a numbing medicine (bupivacaine) for pain relief. Doctors will adjust the dose for each patient to see what works best. The goal is to control pain while using as little medicine as possible.

This study compares two different nerve block methods (iPACK and BiFeS) for pain relief after total knee replacement surgery. 74 adults having knee replacement will receive one of the two blocks along with a standard adductor canal block. The goal is to see which approach leads t…

This study looks at whether taking sitz baths (soaking the pelvic area in warm water) after surgery for pelvic organ prolapse helps reduce pain and improve recovery. About 112 women will be randomly assigned to either a sitz bath routine or standard care. The main goal is to meas…

This study looks at whether teaching patients about how pain works (called Pain Neuroscience Education) can improve recovery after rotator cuff surgery. About 45 adults aged 40-75 will be split into three groups: standard rehab, pain education before surgery, or pain education af…

This study tests two sedative drugs, remimazolam and midazolam, in 120 adults aged 65 and older having orthopedic surgery with regional anesthesia. The goal is to see which drug provides better sedation and causes fewer memory or thinking problems shortly after surgery. Neither p…

This study tests two different ultrasound-guided nerve blocks given before lumbar microdiscectomy surgery to see which provides better pain control. 80 adults aged 18-65 will be randomly assigned to receive one of the two blocks. The main goal is to measure how much opioid pain m…

This study compares two types of nerve blocks—the standard PENG block and a newer iliopsoas plane block (IPB)—for pain control after hip replacement surgery. About 118 adults will receive one of the blocks before surgery, and researchers will measure pain during movement 6 hours …

This study tests if a drug called Anrikefon can control pain after eye surgery as well as a standard painkiller, but with fewer side effects like drowsiness. About 204 adults having eye surgery under general anesthesia will receive either Anrikefon or the standard drug during the…

This study looks at two methods to control pain after a single-level lumbar discectomy (back surgery). One is a newer ultrasound-guided nerve block (QIPB), the other is standard wound infiltration. Researchers will follow 60 adults for 24 hours after surgery to measure pain level…

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can reduce pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will be randomly assigned to receive the combo, o…

This study observes 500 adults aged 65 and older having major abdominal surgery to see if those who receive an ultrasound-guided nerve block for pain have fewer lung complications within 7 days after surgery. The choice of pain management is made by the care team, not the study. …

This study looks at two ways to numb the belly area for gallbladder surgery. Researchers will test 40 adults to see how much skin each method numbs and how long the numbness lasts. The goal is to learn which technique works better for pain control after surgery.