POSTOPERATIVE PAIN MANAGEMENT

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can lower inflammation and pain after major spine surgery. About 50 adults having long-segment spinal fusion will be randomly assigned to receive the stimulation or standard care. Researchers…

This study looks at two common ways to manage pain after umbilical hernia surgery: an ultrasound-guided TAP block and a single-dose epidural. Researchers will measure pain levels in 30 adults at different times after surgery using a simple 0-10 pain scale. The goal is to see whic…

This study looks at whether adding a TAP block (a numbing injection in the belly wall) to standard pain relief helps women recover better after a planned C-section. 150 women will be observed, with half getting the extra block. Researchers will measure recovery quality, pain, and…

This study compares two types of nerve blocks—rhomboid intercostal and serratus posterior superior—to see which one controls pain better after video-assisted lung surgery. Forty adults having elective wedge resection or biopsy will receive one of the blocks with bupivacaine. Thei…

This study tests two different ways to numb the back of the knee after total knee replacement surgery. Both methods are combined with a standard front-of-thigh block. The goal is to see which approach leads to better overall recovery, less pain, and less need for strong painkille…

This study compares two types of nerve blocks (ESPB and SPSIPB) to see which provides better pain relief after coronary artery bypass surgery. About 64 adults aged 45-85 will receive one of the blocks before surgery, and their pain levels, opioid use, and recovery speed will be t…

This study is testing different amounts of the numbing medicine bupivacaine to find the smallest dose that still works for a nerve block after lung surgery. About 27 adults having video-assisted lung surgery will get an ultrasound-guided nerve block before surgery, and the dose w…

This study compares two types of nerve blocks—the newer iliopsoas plane block (IPB) and the established PENG block—for controlling pain and helping recovery after total hip replacement. 118 adults will receive one of the two blocks before surgery, and neither they nor their docto…

This study tests whether adding pain neuroscience education (PNE) to standard rehab improves pain, movement, and fear of movement in 45 adults aged 40-75 recovering from rotator cuff surgery. Participants are split into three groups: standard rehab alone, standard rehab plus PNE …

This study tests a new painkiller called Anrikefon in 204 adults having eye surgery under general anesthesia. Researchers want to see if it controls pain as well as the standard drug nalbuphine, but with fewer side effects like drowsiness. Participants get one dose during surgery…

This study compares two types of ultrasound-guided nerve blocks given before lumbar microdiscectomy (a type of back surgery) to see which one provides better pain relief. Eighty adults aged 18-65 will be randomly assigned to receive one of the two blocks. The main goal is to meas…

This study tests whether adding dexmedetomidine to a standard nerve block (using ropivacaine) improves pain control after hip replacement surgery. About 120 adults aged 18-80 will receive either the standard block or the block with added dexmedetomidine. The main goal is to see h…

This study tests a new drug called HSK21542 for pain after hip replacement surgery. About 405 adults will receive either HSK21542, morphine, or a placebo. The goal is to see if HSK21542 reduces pain better and causes fewer side effects like nausea and vomiting.

This study compares two painkiller combinations—dezocine plus sufentanil versus nalbuphine plus sufentanil—for pain relief after oral cancer surgery with flap reconstruction. Sixty adults will receive one of the two combinations through a patient-controlled pump. The goal is to s…

This study compares two pain relief methods for women having laparoscopic hysterectomy: a spinal injection of morphine versus numbing medicine injected into the belly and surgical sites. The goal is to see which approach provides better recovery, less pain, and fewer side effects…

This study tests whether taking warm water sitz baths for 10 minutes each night for a week can reduce pain after pelvic organ prolapse repair. 112 women will be randomly assigned to sitz baths or standard care. The main goal is to measure pain intensity one week after surgery usi…

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can reduce pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will receive either the combo, one drug alone, or…

This study tests two sedative drugs, remimazolam and midazolam, in adults aged 65 and older having orthopedic surgery with regional anesthesia. The goal is to see which drug provides better sedation during surgery and causes fewer problems with thinking and memory shortly after. …

This study watches 500 adults aged 65 and older who are having major abdominal surgery. It compares those who get an ultrasound-guided nerve block for pain relief to those who get standard pain management. The goal is to see if the nerve block group has fewer lung complications w…

This study looks at two different nerve blocks used to manage pain after gallbladder removal surgery. Researchers will map where on the skin each block causes numbness and see which one covers the surgical cuts better. The goal is to learn more about these blocks to improve pain …