POSTOPERATIVE PAIN MANAGEMENT

This study tests a non-invasive device that gently stimulates a nerve in the ear to see if it can reduce pain and the need for strong painkillers after complex spinal surgery. About 98 adults will be randomly assigned to receive either the real stimulation or a sham (fake) versio…

This study tests three different pain relief methods for people having laparoscopic gallbladder surgery. The goal is to find which method reduces pain and the need for strong opioid drugs. About 132 adults will be randomly assigned to receive either a local numbing injection, a n…

This study tests whether a new painkiller called Suzetrigine can reduce the need for opioids after common knee surgery while still controlling pain well. About 140 adults having ACL reconstruction will be randomly assigned to receive either Suzetrigine or standard opioid painkill…

This study tests whether giving a numbing injection at two spots in the back works better than one spot for pain after lumbar fusion surgery. Sixty adults will be randomly assigned to receive either a single-level or two-level nerve block. Researchers will measure pain scores and…

This study aims to find the best dose of methadone to control pain after heart surgery. About 69 adults having elective heart surgery will receive one of three methadone dosing strategies. Researchers will measure methadone levels in the blood and track pain scores to determine t…

This study looks at two types of pain blocks given after a C-section to see which one helps mothers recover better. Researchers will review the medical records of 60 women who had either an erector spinae plane block or a retrolaminar block. They will measure recovery quality, pa…

This study looks at 120 adults having lung surgery to see which pain management method works best: a nerve block (SPSIPB), an epidural, or standard opioid painkillers. The goal is to find the approach that reduces pain and the need for strong medications. Results will help doctor…

This study tests whether placing small beads containing an antibiotic and pain relievers directly into the surgical site during spine surgery can improve recovery. About 100 adults having elective lumbar fusion will be randomly assigned to get beads with antibiotic alone or beads…

This study will compare two types of nerve blocks (ESPB and SPSIPB) to see which one works better for pain after heart bypass surgery. About 64 adults aged 45-85 will be randomly assigned to receive one of the blocks before surgery. The main goal is to measure pain levels at diff…

This study compares two approaches to manage pain after vaginal hysterectomy: a combination of two intravenous drugs (dexmedetomidine and ketamine) versus dexmedetomidine alone. Fifty women undergoing the surgery under spinal anesthesia will participate. The goal is to see which …

This study tests whether adding a second nerve block (biceps femoris short head block) to the standard adductor canal block provides better pain relief after total knee replacement. Sixty adults having knee surgery will be randomly assigned to receive either the combination block…

This study tests two pain-relief methods after open inguinal hernia surgery: an ultrasound-guided nerve block (TFPB) versus the surgeon injecting numbing medicine into the wound. About 104 adults will be randomly assigned to one of the two groups. The goal is to see which method …

This study will measure how much opioid pain medicine patients need after chest surgery (thoracotomy) and look at what affects their pain. Researchers will follow 35 adults to see how pain medicine use relates to complications and how long they stay in the hospital. The goal is t…

This study watches 30 older adults (65+) having lung surgery with one-lung breathing to see if drops in brain oxygen affect their thinking and pain afterward. Researchers measure brain oxygen during surgery and test memory and pain levels for a week. The goal is to learn how to b…

This study looks at how far from the anus and how deep doctors need to insert a needle to numb the pudendal nerve in children having penile surgery. Researchers will measure these distances in 50 children aged 1-18 and see how they relate to age, height, and weight. The goal is t…

This study looks at how diabetes affects a type of numbing shot called an ankle block, used during foot or ankle surgery. Researchers will compare 46 diabetic and non-diabetic adults to see how quickly the block works and how much pain medicine they need afterward. The goal is to…