New drug aims to cut opioid use after common knee surgery
NCT ID NCT07355166
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This study tests whether a new painkiller called suzetrigine can help people use fewer opioids after ACL surgery while still controlling pain. About 140 participants will receive either suzetrigine or standard opioid-based pain care and report their pain, opioid use, and side effects for one week. The goal is to see if suzetrigine can provide effective pain relief with less reliance on opioids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Suzetrigine (Journavx)
- What this could lead to
- If successful, this could offer a way to manage post-surgery pain with fewer opioids, reducing addiction risk.
- What could go wrong
- This is a small, early-phase trial focused on a specific surgery. Results may not apply to other procedures, and suzetrigine may not control pain as well as opioids.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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