New injection could ease pain after hip replacement
NCT ID NCT07186426
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 33 times
Summary
This phase 3 trial tests a new drug called HSK21542 for pain after orthopedic surgery like hip replacement. About 405 adults will receive either HSK21542, morphine, or a placebo. The goal is to see how well it controls pain and what side effects occur.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Xiangya Hospital of Central South University
RECRUITINGChangsha, Hunan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xuanwu Hospital Capital Medical University
RECRUITINGBeijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HSK21542 injection
What this could lead to
If it works, this could provide a new option for managing pain after orthopedic surgery with possibly fewer side effects than current treatments.
What could go wrong
This is still an experimental drug. Even if it works, it may not be better than existing painkillers, and side effects are unknown at this stage.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.