New pain combo may improve recovery after oral cancer surgery

NCT ID NCT07401641

Recruiting now Symptom relief Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two painkiller combinations—dezocine plus sufentanil versus nalbuphine plus sufentanil—for pain relief after oral cancer surgery with flap reconstruction. Sixty adults will receive one of the two combinations through a patient-controlled pump. The goal is to see which provides better pain control, fewer side effects, and better flap survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dezocine and nalbuphine (opioid painkillers)
What this could lead to: If it works, this could identify a safer, more effective pain management option for oral cancer patients after surgery.
What could go wrong: This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The drugs are already approved, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for FREE TISSUE FLAPS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

lip and oral cavity carcinoma Mouth Neoplasms oral cavity neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FREE TISSUE FLAPS MOUTH NEOPLASMS ORAL CANCER POSTOPERATIVE PAIN MANAGEMENT

Contacts and locations

Locations

Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen Universit
RECRUITING

Guangzhou, Guangdong, 510000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.