New combo could cut opioid use after hip replacement

NCT ID NCT07316166

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding dexmedetomidine to a standard nerve block (using ropivacaine) improves pain control after hip replacement surgery. About 120 adults aged 18-80 will receive either the standard block or the block with added dexmedetomidine. The main goal is to see how long it takes before patients need their first painkiller after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Dexmedetomidine
What this could lead to
If it works, this could lead to better pain relief and less opioid use after hip surgery.
What could go wrong
This is a small, early-phase study, so results may not apply to everyone. Adding dexmedetomidine may cause side effects like low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Miriam Hospital

    RECRUITING

    Providence, Rhode Island, 02906, United States

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