Which sedative is kinder to the aging brain after surgery?

NCT ID NCT07113483

Recruiting now Symptom relief Sponsor: Romanian Society for Enteral and Parenteral Nutrition Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two sedative drugs, remimazolam and midazolam, in adults aged 65 and older having orthopedic surgery with regional anesthesia. The goal is to see which drug provides better sedation during surgery and causes fewer problems with thinking and memory shortly after. 120 participants will be randomly assigned to one of the two drugs, and neither they nor their doctors will know which one they received. The results will help doctors choose the safest sedative for older patients.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction hip fracture injury Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIP FRACTURE ORTHOPEDIC PROCEDURES POSTOPERATIVE COGNITIVE DYSFUNCTION POSTOPERATIVE PAIN MANAGEMENT

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Clinical Emergency Hospital of Bucharest
RECRUITING

Bucharest, Romania

Contact Phone: •••-•••-•••• Email: •••••@•••••