Can a nerve block replace opioids after gallbladder surgery?
NCT ID NCT07750769
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial tests whether combining an opioid-free anesthesia protocol with a specific nerve block can control pain after laparoscopic gallbladder removal. Half of the participants will receive the nerve block plus opioid-free anesthesia, while the other half will receive only the opioid-free protocol. The study measures how much extra opioid painkiller is needed in the first six hours after surgery, aiming to see if the nerve block reduces opioid consumption.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Opioid-free anesthesia protocol combined with an ultrasound-guided external oblique intercostal plane (EOI) nerve block
- What this could lead to
- If successful, this approach could reduce opioid use after gallbladder surgery, lowering the risk of opioid-related side effects and dependence.
- What could go wrong
- This is a small, early-stage trial, and the nerve block may not provide enough pain relief for all patients. There are also risks of bleeding, infection, or local anesthetic allergy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.