Can a One-Time brain surgery free children from a lifetime of shunts?
NCT ID NCT07735936
First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This trial tests whether a combined surgical procedure — endoscopic third ventriculostomy plus choroid plexus cauterization (ETV+CPC) — can effectively treat hydrocephalus in children without needing a permanent shunt. The surgery aims to create a new fluid pathway and reduce fluid production inside the brain. Researchers will enroll 90 children under 18 with obstructive hydrocephalus to see how long they remain shunt-free and to compare outcomes across different causes of the condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- combined endoscopic third ventriculostomy and choroid plexus cauterization (ETV+CPC) surgical procedure
- What this could lead to
- If successful, this combined surgery could offer children with hydrocephalus a lasting treatment without a permanent shunt, reducing infections and repeat surgeries.
- What could go wrong
- This is a single-center study with 90 participants, and success may vary by age and cause of hydrocephalus. The surgery carries standard surgical risks like infection or bleeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assuit University Hospital
Asyut, Asyut Governorate, 71515, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.