One-and-Done stone surgery could spare kidney patients a second procedure

NCT ID NCT07177313

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at whether it is safe to remove kidney stones right away in people whose kidneys are not working well due to the blockage. Normally, doctors place a temporary tube first to protect the kidney, but this adds extra procedures and visits. The trial will enroll 60 adults with a single blocked ureter and reduced kidney function, and will check for complications and how well the stone is cleared. If it works, patients could get faster relief and avoid a second surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ureteroscopy (a minimally invasive procedure to remove stones from the ureter)

What this could lead to

If successful, this could show that immediate stone removal is safe for patients with reduced kidney function, allowing faster relief and fewer procedures.

What could go wrong

This is a small, early feasibility study with only 60 participants and no randomization, so results may not apply broadly. Risks include infection, bleeding, or injury from the procedure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

obstructive nephropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.