One-and-Done stone surgery could spare kidney patients a second procedure

NCT ID NCT07177313

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at whether it is safe to remove kidney stones right away in people whose kidneys are not working well due to the blockage. Normally, doctors place a temporary tube first to protect the kidney, but this adds extra procedures and visits. The trial will enroll 60 adults with a single blocked ureter and reduced kidney function, and will check for complications and how well the stone is cleared. If it works, patients could get faster relief and avoid a second surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ureteroscopy (a minimally invasive procedure to remove stones from the ureter)
What this could lead to
If successful, this could show that immediate stone removal is safe for patients with reduced kidney function, allowing faster relief and fewer procedures.
What could go wrong
This is a small, early feasibility study with only 60 participants and no randomization, so results may not apply broadly. Risks include infection, bleeding, or injury from the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.