Heart drug showdown: new combo pill vs old standard in kids

NCT ID NCT07197372

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two heart failure medications—sacubitril/valsartan (a newer combo drug) and captopril (an older drug)—in 70 children aged 1 month to 18 years with dilated cardiomyopathy (an enlarged, weak heart). The goal is to see which drug better improves the heart's pumping ability over 12 months. Children must be stable on other heart therapies before joining, and those with severe kidney problems or allergies to the drugs cannot participate.

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Conditions

The condition(s) this trial relates to.

dilated cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.