Can a second dose of radioactive iodine catch hidden thyroid cancer?

NCT ID NCT07453225

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving more radioactive iodine can help people with differentiated thyroid cancer whose tumor marker (thyroglobulin) is high but whose scans show nothing. One hundred adults who have already had their thyroid removed and one round of radioactive iodine will get an extra dose. The main goal is to see if the tumor marker drops after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radioactive iodine

What this could lead to

If it works, this could offer a way to control thyroid cancer when standard scans show nothing.

What could go wrong

This is an early-phase trial with only 100 people, so results may not apply widely. The treatment may not lower tumor markers or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

differentiated thyroid carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••