Can a second dose of radioactive iodine catch hidden thyroid cancer?
NCT ID NCT07453225
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving more radioactive iodine can help people with differentiated thyroid cancer whose tumor marker (thyroglobulin) is high but whose scans show nothing. One hundred adults who have already had their thyroid removed and one round of radioactive iodine will get an extra dose. The main goal is to see if the tumor marker drops after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radioactive iodine
- What this could lead to
- If it works, this could offer a way to control thyroid cancer when standard scans show nothing.
- What could go wrong
- This is an early-phase trial with only 100 people, so results may not apply widely. The treatment may not lower tumor markers or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIFFERENTIATED THYROID CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could drug holidays improve thyroid cancer treatment?
- Radiation safety study aims to personalize thyroid cancer treatment
- Which neck surgery hurts least? new study aims to find out
- New scoring system could rate robot thyroid surgeons
- Radioactive iodine: unnecessary for some thyroid cancer patients?
- New model aims to predict tough thyroid surgeries before they start