BREAST CANCER

This early-stage study tested a new approach for treating breast cancer before surgery. It combined a shorter, more intense course of targeted radiation (CyberKnife) with chemotherapy drugs. The main goal was to find the safest and most effective radiation dose to shrink tumors, …

This early-stage study tested a combination of three drugs given to postmenopausal women before breast cancer surgery. The goal was to see if the drugs—two approved and one experimental—could safely shrink tumors by attacking the cancer in different ways. Researchers enrolled 15 …

This study tested whether adding the diabetes medication metformin to tamoxifen treatment could reduce thickening of the uterine lining in postmenopausal breast cancer patients. Researchers compared 60 women taking tamoxifen plus metformin against those taking tamoxifen plus a pl…

This study tested whether giving very high doses of chemotherapy, followed by a patient's own stem cells to 'rescue' their immune system, could better treat a rare and aggressive form of breast cancer called inflammatory breast carcinoma. It involved 41 patients with stage IIIB d…

This study tested whether adding a drug called nintedanib to standard chemotherapy (docetaxel) could help control advanced breast cancer for longer. It involved 51 adults with HER2-negative breast cancer that had returned or spread, who were starting their first or second round o…

This study looked at how three already-approved breast cancer drugs work for Egyptian patients in real-world hospital settings, not just in controlled trials. Researchers followed 206 women with advanced, hormone-sensitive breast cancer to see how long the drugs kept the cancer f…

This study tested whether adding an experimental drug called samuraciclib to the standard hormone therapy fulvestrant could better control advanced breast cancer that has stopped responding to prior treatments. It involved 60 adults with hormone receptor-positive, HER2-negative b…

This study tested whether adding a specialized geriatric care team to standard cancer treatment could help older patients. It involved 792 patients aged 70 and older with various advanced cancers. The goal was to see if this coordinated care approach improved survival and quality…

This study tested whether adding an experimental drug called ganetespib to the standard hormone therapy fulvestrant could better control advanced breast cancer that had stopped responding to other hormone treatments. It involved 50 people with hormone receptor-positive, HER2-nega…

This study tested whether a short course of talk therapy for insomnia could help breast cancer survivors take their hormone-blocking medication more consistently. Poor sleep is a common side effect of this essential medication, which can lead people to skip doses and increase the…

This study tested if adding a nurse practitioner trained in diabetes care to a cancer treatment team could help patients better manage their diabetes while undergoing breast cancer treatment. It involved 74 adults with breast cancer and either prediabetes or type 2 diabetes. The …

This was a first-in-human study to find a safe dose of a new experimental cancer drug called SNB-101. The drug, a nanoparticle form of an existing chemotherapy, was given by IV to 21 patients with advanced solid tumors that had stopped responding to standard treatments. The main …

This study tested if a technique used in organ transplants could improve outcomes for breast reconstruction surgery. In 18 women who had a mastectomy for breast cancer, surgeons briefly interrupted and restored blood flow to the abdominal tissue flap before using it for reconstru…

This study tested whether a new drug called giredestrant works as well as or better than standard treatment for premenopausal women with early-stage, hormone-sensitive breast cancer. Researchers compared three treatment approaches over four weeks before surgery in 231 participant…

This study monitored the safety of LYNPARZA, a medication given after surgery to help prevent breast cancer from returning in high-risk patients. Researchers tracked 61 patients with specific genetic mutations to see how often they experienced bone marrow suppression, a known sid…

This study tested a specific sequence of four chemotherapy drugs given before surgery (neoadjuvant therapy) for people with triple-negative breast cancer, a type that doesn't respond to hormone therapies. The main goal was to see if this treatment could completely eliminate the i…

This study tested an oral drug called neratinib for people with a specific type of breast cancer (HER2-positive) that had spread to the brain. The main goal was to see if neratinib could shrink or stabilize the brain tumors. Researchers also measured how much of the drug reached …

This study tested whether giving two preventive medications (loperamide for diarrhea and G-CSF for low white blood cells) alongside the cancer drug sacituzumab govitecan could reduce its common and severe side effects. It involved 50 adults with advanced triple-negative or lumina…

This first-in-human study tested a new oral drug called JAB-3312 in 40 adults with advanced solid tumors that had progressed despite standard treatments. The main goals were to find the safest dose and see how the body processes the drug. Researchers also looked for early signs t…

This study tested if adding a new, targeted drug to standard hormone therapy could better slow the growth of certain breast tumors before surgery. It involved 19 people with a specific type of breast cancer. The goal was to see if matching the drug to the tumor's genetic profile …

This first-in-human study tested a new oral drug called RP903 in people with advanced cancers that had stopped responding to standard treatments. The main goals were to find a safe dose and see how the body processes the drug. The study focused on specific cancers, including ovar…

This study tested if giving a heart medication called carvedilol to breast cancer patients at higher risk of heart damage could protect their hearts during chemotherapy. It involved 68 women receiving specific cancer drugs (doxorubicin and/or trastuzumab). The goal was to see if …

This study tested the safety of adding an oral drug called rucaparib to the standard radiation therapy given after surgery. It involved 31 women with a hard-to-treat type of breast cancer that had not fully disappeared after initial chemotherapy. The main goal was to find a safe …

This study looked back at existing medical records to compare how long patients lived after receiving two different treatments for advanced breast cancer. It included 779 Medicare patients aged 65 and older whose cancer had already spread when first diagnosed. Researchers analyze…

This study looked at how well the drug ribociclib worked in real-world settings for 335 Indian women with advanced breast cancer. Researchers analyzed medical records from 18 hospitals to understand how long the treatment kept the cancer from worsening and what side effects patie…

This study monitored side effects in breast cancer patients who received a precise, targeted radiation boost during their standard treatment after breast-conserving surgery. Researchers followed 93 patients to track both short-term and long-term side effects from this technique. …

This study tested whether adding a common antibiotic called moxifloxacin to standard chemotherapy could help prevent breast cancer from coming back after surgery. Over 550 patients who had surgery for breast cancer were randomly assigned to receive either the antibiotic or a plac…

This study tested a new follow-up program called REASSURE for people who have finished treatment for early-stage, low-risk breast cancer. The goal was to see if the program helps survivors feel more prepared and confident in managing their health after cancer, while potentially r…

This small study tested whether using focused ultrasound to temporarily open the blood-brain barrier is safe and possible. The barrier normally protects the brain but can block cancer drugs. Eight patients with breast cancer that had spread to the brain received the ultrasound tr…

This first-in-human study tested the safety of a new treatment called pulsed electromagnetic fields (PEMF) in breast cancer patients. Fourteen patients received a 30-minute PEMF session alongside their standard chemotherapy or before surgery. The main goal was to check for side e…

This study tested whether injecting a modified virus directly into breast tumors, combined with an immunotherapy drug, could help eliminate remaining cancer cells in women who still had cancer after standard chemotherapy before surgery. The trial involved 28 women with early-stag…

This study created a registry to track the long-term results of a specific radiation technique for breast cancer. Over 1,100 patients in Germany received a targeted dose of radiation directly to the tumor site during their surgery, followed by a shorter course of standard externa…

This early-stage study tested a new oral drug called ART4215 in people with advanced or metastatic solid tumors, including breast cancer. The main goals were to find a safe dose for the drug when taken alone and when combined with other cancer drugs, and to check for early signs …

This small, completed study tested a combination of two drugs for people with advanced breast cancer linked to specific inherited gene changes (BRCA or HDR defects). The goal was to see if using an immunotherapy drug (pembrolizumab) together with a targeted therapy (olaparib) cou…

This large, completed Phase 3 trial tested if a newer hormone therapy combination (exemestane + triptorelin) was better than the standard combination (tamoxifen + triptorelin) at preventing cancer from coming back in premenopausal women with early-stage, hormone-responsive breast…

This study tested whether adding the drug enzalutamide to standard hormone therapy (exemestane) could better control advanced breast cancer. It involved 247 postmenopausal women whose cancer had specific hormone receptors but normal HER2 levels. Researchers compared the combinati…

This study tested a new automated system that uses MRI scans to guide radiation therapy for breast cancer. The goal was to see if this approach could make treatment more precise and faster for patients. It involved 63 women with breast cancer who were already scheduled for standa…

This study tested whether adding a new drug called PF-07220060 to standard hormone therapy (letrozole) works better than letrozole alone to shrink breast tumors before surgery. It involved 121 postmenopausal women with a specific type of breast cancer (HR-positive, HER2-negative)…

This study tested whether giving breast cancer patients a personalized dose of vitamin D, based on their individual deficiency level, works better than a standard one-size-fits-all dose to correct the deficiency. It involved 215 patients who had recently finished chemotherapy. Th…

This study tested a personalized counseling program to help breast cancer survivors manage their weight and improve their health. The program combined in-person and phone-based coaching on diet and exercise. Researchers wanted to see if this more convenient approach could help pa…

This study tested whether a shorter radiation schedule (fewer, larger doses) works as well as the standard longer schedule for early-stage breast cancer patients after breast-conserving surgery. It involved 720 patients who were randomly assigned to receive one of the two radiati…

This study tested whether a more targeted form of radiation therapy could reduce damage to breast implants in women who had reconstructive surgery after breast cancer. Researchers compared a new technique using many small, precise radiation beams to the standard method, hoping it…

This completed Phase 3 trial tested whether a new drug combination (eribulin + pertuzumab + trastuzumab) could control advanced HER2-positive breast cancer as well as the standard treatment (taxane + pertuzumab + trastuzumab), but with better quality of life. It involved 446 wome…

This study observed 562 premenopausal Chinese women who had surgery for hormone-sensitive breast cancer. Researchers compared how two different schedules of hormone-blocking injections (given every 1 month vs. every 3 months) affected patients' quality of life and their ability t…

This study tested if adding atorvastatin, a common cholesterol-lowering drug, to standard hormone therapy could better control advanced breast cancer. It involved 126 women with hormone-sensitive, advanced breast cancer to see if the combination delayed cancer growth longer than …

This study tested a non-surgical treatment for older adults with breast cancer who could not or did not want to have an operation. Doctors used ultrasound to guide a needle that heats and destroys the tumor, combined with hormone-blocking pills. The goal was to see if this approa…

This study tested if a newer drug called T-DM1 causes fewer serious side effects than the standard two-drug combination (paclitaxel and trastuzumab) for early-stage HER2-positive breast cancer. It involved 512 women who had recently had breast cancer surgery. The main goals were …

This study tested whether combining two drugs, samuraciclib and elacestrant, is safe and effective for people with advanced hormone-positive, HER2-negative breast cancer that has progressed on standard therapy. It involved 49 adult participants internationally. The trial first ai…

This study tested whether a shorter, 15-session course of proton radiotherapy is as safe and effective as a standard 25-session course for patients who had a mastectomy and need radiation to the chest wall and lymph nodes. It involved 88 women with breast cancer and aimed to see …

This study compared two shorter radiation schedules for women with early-stage breast cancer who had breast-conserving surgery. One group received radiation in 5 sessions over 1 week, while the other received 15 sessions over 3 weeks. Researchers followed 60 participants for up t…

This study tested whether a special mobile phone app could help women with early breast cancer follow their prescribed treatment plans more closely and feel better during recovery. Researchers randomly assigned 540 patients to either use the app, which provided reminders, educati…

This study tested a shorter radiation treatment schedule that delivers higher doses directly to the tumor area while protecting healthy tissue. It involved 35 women with early breast cancer who had undergone breast-conserving surgery. The main goal was to check how safe this appr…

This study tested a new, less invasive surgical technique for breast reconstruction after preventive mastectomy. It involved 20 women at high genetic risk for breast cancer. The goal was to place the implant using a small camera through a single incision in the armpit, avoiding t…

This study tested whether adding a drug called darsilide to standard hormone therapy could help shrink tumors in premenopausal women with a specific type of breast cancer. The trial involved 119 women whose cancer hadn't responded well to initial chemotherapy. Researchers measure…

This small, early-stage study tested a combination of chemotherapy (nab-paclitaxel) and an immunotherapy drug (pembrolizumab) as a treatment before surgery for a common type of breast cancer. The main goal was to see how this combination changed a specific marker (PD-L1) on the p…

This study tested whether adding the drug ribociclib to standard hormone therapy helps control advanced breast cancer longer in Chinese women. It involved 327 premenopausal and postmenopausal women with hormone receptor-positive, HER2-negative breast cancer that had spread or ret…

This study looked at how an 8-week virtual program focused on healthy eating and activity affected breast cancer survivors. Twenty-two participants attended weekly online sessions and completed surveys and health checks. Researchers measured stress, lifestyle habits, mental healt…

This study tested whether injecting a specially modified cold sore virus directly into breast tumors during chemotherapy before surgery could help eliminate cancer more effectively. The virus is designed to attack cancer cells and may help the patient's own immune system fight th…

This study tested if adding an immunotherapy drug (pembrolizumab) to a standard chemotherapy (carboplatin) could better control breast cancer that had returned to the chest wall. It involved 76 patients whose cancer had stopped responding to prior hormone therapies or was a type …

This study tested whether montelukast, a common asthma medication, could help protect the heart from damage caused by the chemotherapy drug doxorubicin in breast cancer patients. Fifty patients were split into two groups: one received montelukast and the other received a placebo …

This study tested a combination of three drugs—paclitaxel, trastuzumab, and pertuzumab—given to patients before surgery for a fast-growing type of breast cancer called inflammatory breast cancer. The main goals were to see if the treatment could completely eliminate the cancer fr…

This early-stage study tested a new drug called FS1502 in people with advanced cancers that have a specific marker called HER2. The trial first checked if different doses were safe for various solid tumors, then focused on patients with advanced HER2-positive breast cancer who ha…

This study looked back at medical records of 1,000 women who had breast reconstruction after mastectomy and radiation. Researchers compared two types of implants to see which caused fewer problems like hardening around the implant or implant loss. The goal is to help doctors choo…

This study tested whether a special support program helps women aged 70+ stick to their breast cancer hormone therapy. The program included weekly Tai Chi, nutritional advice, vitamin D checks, and regular medical follow-ups to manage joint pain and other side effects. Researcher…

This study looked at how two newer, targeted breast cancer drugs performed in everyday medical practice, not just in controlled trials. It followed 312 patients with advanced breast cancer who had already tried other treatments. The main goal was to understand the real-world safe…

This study compared two different follow-up care plans for people who had finished their main breast cancer treatment. It tested whether a personalized schedule, potentially with fewer clinic visits, was as good as a standard guideline-based schedule. The main goal was to see if …

This study compared two different dosing schedules for the drug palbociclib when combined with standard hormone therapy for advanced breast cancer. Researchers wanted to see if a lower daily dose (100 mg every day) would work as well or better than the standard schedule (125 mg f…

This study tested an online program designed to help breast cancer survivors feel more positive and less negative about their anti-hormonal medication. The goal was to see if improving their emotional outlook could help them take their medication more consistently to prevent canc…

This early-stage study tested a new cancer vaccine designed to teach the body's immune system to recognize and attack tumors. It involved 43 people with advanced colorectal, lung, breast, or prostate cancer that had stopped responding to standard treatments. The main goals were t…

This early-phase study tested whether combining a short, intense course of radiation with two immunotherapy drugs is safe for patients with advanced cancers that have spread. The trial involved 53 adults with metastatic melanoma, lung, breast, or pancreatic cancer who had tried o…

This completed Phase 3 trial tested whether a new oral drug called elacestrant works better than standard hormone therapies for people with advanced breast cancer that has grown despite previous treatments. The study involved 478 men and postmenopausal women whose cancer had spec…

This large, completed study tested whether adding a new drug called pertuzumab to the standard treatment (chemotherapy plus trastuzumab) was better at preventing breast cancer from coming back after surgery. It involved over 4,800 women with a specific type of operable, HER2-posi…

This early-stage study tested the safety of combining two drugs, ARV-471 and everolimus, for people with advanced breast cancer that has stopped responding to standard hormone therapies. It involved 32 participants to find the safest and most effective dose for future research. T…

This study tested whether a lower starting dose of the drug ribociclib, when combined with standard hormone therapy, could effectively control advanced breast cancer while potentially causing fewer side effects. The trial involved 376 women with hormone-sensitive, HER2-negative a…

This study tested whether a single, precise radiation treatment using CyberKnife technology could replace multiple standard radiation sessions given after lumpectomy for early-stage breast cancer. Researchers wanted to see if this approach could reduce skin redness, swelling, and…

This study looked at whether the type of anesthesia used during breast cancer surgery affects the body's immune response and recovery. Researchers compared general anesthesia (putting you to sleep) to a targeted nerve block (numbing only the chest area) in 50 patients. They measu…

This study tested whether adding the drug alpelisib to standard hormone therapy could help control advanced breast cancer that had a specific genetic change (PIK3CA mutation) and had worsened despite prior treatments. It involved 383 men and women whose cancer was hormone-recepto…

This study tested whether a new targeted drug called trastuzumab deruxtecan (DS-8201a) works better than standard treatments for people with advanced HER2-positive breast cancer that has spread and stopped responding to a previous targeted therapy. It involved 608 adults whose ca…

This study tested whether it is safe to lower the high dose of the steroid dexamethasone given to patients before docetaxel chemotherapy. It involved 46 people with breast or prostate cancer. The goal was to find the lowest effective steroid dose to prevent allergic and swelling …

This study observed how well the breast cancer drug T-DM1 works and how safe it is in everyday medical practice in China. It followed 178 patients with advanced HER2-positive breast cancer who had already tried other treatments. Researchers tracked side effects and how long the t…

This early-stage study tested a new chemotherapy drug called WH002 against a standard drug (paclitaxel) for women with HER2-negative breast cancer. The goal was to see if WH002, given before surgery along with other drugs, was safer or worked better at shrinking tumors. The trial…

This study tested whether analyzing specific genetic markers in breast tissue samples could help doctors more accurately diagnose lesions that are difficult to classify. Researchers examined tissue from 301 women with suspicious breast lesions to see if the molecular test results…

This study compared two methods to help surgeons find small, non-palpable breast tumors before removal. 350 participants were randomly assigned to have their tumor marked either with a standard metal wire or a tiny radioactive iodine seed. Researchers wanted to see if the seed me…

This study tested whether contrast-enhanced mammography (CEM) could work as an alternative screening method for women who need breast MRI but can't get one. Researchers enrolled 601 women who couldn't have MRI due to claustrophobia, medical implants, body size, or cost issues. Th…

This study tested new blood tests designed to detect specific cancer biomarkers in patients with metastatic ER+/HER2- breast cancer. It involved 30 participants who provided blood samples and tumor tissue to see if the tests could accurately identify genetic changes in the cancer…

This study compared two advanced imaging tests to see which is more accurate for detecting breast cancer. It involved 231 women in Quebec who had a suspicious breast lump. Researchers tested both contrast-enhanced mammography (CESM) and MRI scans, then checked the results against…

This study tested a technique called sentinel lymph node mapping in women with breast cancer that appeared in multiple spots (multifocal). Researchers wanted to see if this mapping method could accurately identify the first lymph nodes where cancer might spread, to help guide sur…

This study tested if a special PET scan could tell early on whether breast cancer chemotherapy was working. Researchers scanned 63 patients before and after their first chemo cycle. They compared the scan results to the tumor's actual response after three full cycles to see if th…

This study tested whether an AI software tool called CadAI-B Dx helps doctors interpret breast ultrasound scans more accurately. Sixteen doctors reviewed 797 patient scans, first without the AI and then with its assistance, to see if it improved their ability to correctly identif…

This study tested whether MRI scans could more accurately measure the size of a very early form of breast cancer called DCIS. It involved 40 women with DCIS who received both an MRI and a standard mammogram. The goal was to see if MRI could give surgeons a clearer picture of the …

This study tested whether using extra imaging methods could better detect if breast cancer had spread to the lymph nodes under the arm. It involved 180 women with breast cancer who received these additional scans alongside their standard tests. The goal was to improve the accurac…

This study tested whether a new artificial intelligence (AI) tool could accurately measure a specific heart rhythm interval (QTc) from electrocardiograms (ECGs). The research involved 70 women with breast cancer who were starting treatment with the drug ribociclib, which requires…

This study aimed to create a simple screening tool to identify women at high risk for long-term arm problems after breast cancer surgery and treatment. These problems include chronic pain, swelling (lymphedema), and limited movement. The researchers developed and tested a questio…

This study tested a new microwave imaging device called Wavelia #2 to see if it can detect and measure breast cancer tumors. The device uses safe, non-radiation microwaves to create images based on differences between healthy and cancerous tissue. Researchers enrolled 73 women wi…

This study looked at whether a new 3D measurement method (TDTP-RECIST) works better than the current standard (RECIST 1.1) for tracking how irregularly shaped tumors respond to pre-surgery treatment. Researchers reviewed past medical scans and records of 120 adults with breast, p…

This study aimed to improve a specialized breast biopsy procedure. When a suspicious spot is seen only on a special contrast mammogram, doctors need to take tissue samples. Researchers worked with 77 women to find the minimum number of samples needed to get a reliable diagnosis, …

This study tested a new device called the SmartClip to see if it helps surgeons accurately locate and remove breast tumors during cancer surgery. Doctors placed the clip in the breast before surgery and used a navigation system to find it during the operation. The goal was to see…

This study tested whether a home device that measures body water could help detect early signs of lymphedema (arm swelling) in people who have had breast cancer surgery. Researchers followed 52 participants for a year, having them use the device twice daily to track changes. The …

This study tested whether doctors could accurately check if breast cancer has spread by removing and examining just a few key lymph nodes instead of many. Researchers worked with 20 patients who had advanced breast cancer that had reached their lymph nodes. They wanted to see if …

This study tested a new, non-invasive imaging tool called DOSI that uses harmless near-infrared light to scan breast tumors. The goal was to see if this scan, performed during the first days of chemotherapy, could predict whether the treatment would ultimately be successful. Rese…

This study tested whether an MRI scan could help find breast cancer in women who have suspicious nipple discharge, but whose standard mammograms and ultrasounds look normal. It involved 70 women to see if MRI could accurately rule out cancer when it appears normal. The goal was t…

This study tested whether a simple blood test could predict which breast and prostate cancer patients would develop severe long-term side effects from radiation therapy. Researchers measured how certain immune cells reacted to radiation in the lab. The goal was to identify the 5%…

This study tested a new handheld gamma camera called CarolIReS, used during surgery to help surgeons find and remove the first lymph nodes where breast cancer might spread. It involved 110 patients with early-stage breast cancer. The goal was to see if this camera could improve t…

This study tested a new imaging method to help surgeons during breast-conserving surgery. It involved 206 women with early-stage breast cancer. The goal was to see if a special PET-CT scan of the removed tumor, done right in the operating room, could help the surgeon spot and rem…

This study tested a new ultrasound technique that measures how stiff and stretchy a breast mass is. The goal was to see if this 'Nonlinear Elasticity Mapping' could help doctors better tell if a mass is cancerous or benign without always needing a biopsy. The study involved 172 p…

This study tested whether adding gentle osteopathic manipulative medicine (OMM) techniques to the standard breast massage could help special dyes and tracers flow better to lymph nodes during breast cancer surgery. Better flow helps surgeons more accurately find and test the 'sen…

This large study tested whether adding 3D imaging (tomosynthesis) to standard 2D mammograms improves breast cancer screening. Over 26,000 women aged 45-74 were randomly assigned to receive either the combined 3D/2D test or the standard 2D mammogram alone. The main goal was to see…

This study aimed to find the best way to prevent ovarian cancer in women at high genetic risk. It compared two approaches: preventive surgery to remove the ovaries and fallopian tubes, or close monitoring with a special blood test (CA-125) and ultrasounds. Researchers followed wo…

This study tested whether a time-restricted eating schedule could lower certain blood markers linked to breast cancer risk. It involved 29 postmenopausal women with pre-diabetes who were randomly assigned to eat all their food within an 8-hour window each day or to follow their n…

This study tested two ways to help White Mountain Apache women get recommended mammograms to catch breast cancer early. Researchers compared a culturally tailored education program alone versus that program plus support from an Apache women's health coach. The goal was to see whi…

This early-stage study tested a personalized vaccine designed to teach the immune system to attack breast cancer cells, aiming to prevent the cancer from returning. It involved 15 women with a high-risk form of breast cancer who had no detectable disease after initial treatment. …

This study tested whether simple reminders sent to doctors and patients could increase the use of a special breast MRI scan for women with very dense breast tissue. Dense tissue makes cancer harder to spot on regular mammograms, and this extra scan can find more cancers early. Re…

This study tested an online dance movement therapy program designed to help women with breast cancer during chemotherapy. Researchers wanted to see if regular virtual dance sessions could help patients better understand their emotions and reduce feelings of physical and emotional…

This study tested whether watching 360° virtual reality movies could help reduce fear and anxiety in cancer patients about to begin radiation therapy. Researchers enrolled 292 adults with breast, lung, prostate, head and neck cancers, or brain tumors. Patients watched VR movies s…

This study tested whether a personalized brain training program could help breast cancer patients manage thinking and memory problems (often called 'chemobrain') that can occur during cancer treatment. Fifty patients were randomly assigned to either receive the training program p…

This study tested a new program to help young couples who have faced breast or gynecologic cancer. The program, delivered over video calls, aimed to help partners communicate better and cope with the sexual and fertility challenges that often follow cancer treatment. Researchers …

This study aimed to find the best time of day to take hormone therapy pills for breast cancer to reduce side effects and help patients continue their treatment. Researchers compared taking the medication in the morning versus the evening in 245 patients with early-stage breast ca…

This study tested whether a new survivorship clinic could help women manage symptoms and improve quality of life after completing treatment for early-stage breast or gynecologic cancer. Researchers enrolled 200 women who had finished their primary cancer therapy within the past y…

This study tested a coaching program called PRISM, designed to help women with breast cancer build resilience and manage stress. It involved 43 participants who received skills-based coaching focused on stress management, goal-setting, and positive thinking. The main goal was to …

This study tested whether teaching patients simple self-massage and stretching techniques could help prevent long-term pain after breast cancer surgery. 144 women scheduled for surgery were split into two groups. One group received standard care, while the other also attended wor…

This small pilot study tested whether a smartphone app could help breast cancer survivors learn yogic breathing exercises in group video sessions. Researchers wanted to see if using the app for 12 weeks would help participants stick with the practice and manage common post-treatm…

This study tested whether a gentle, low-intensity vibration platform could help reduce muscle and joint pain, fatigue, and weakness caused by a common breast cancer medication (aromatase inhibitors). For 12 months, 72 early-stage breast cancer survivors either used the vibration …

This small pilot study tested whether a walking program could help reduce fatigue in breast cancer patients undergoing hormone therapy. Seventeen women participated in either supervised group walks or home-based walking for 20 minutes twice weekly over six weeks. Researchers comp…

This study tested whether using technology could help improve care for people with advanced breast cancer who live far from their treatment center. Fifteen patients used tablets to report symptoms weekly and wore smartwatches that tracked their activity and sleep. Researchers wan…

This study tested whether physical therapy helps with shoulder pain, stiffness, and swelling that can occur after breast cancer surgery. Researchers compared women who received physical therapy to those who didn't, measuring shoulder movement, pain levels, and arm function. The g…

This study tested whether taking a Coenzyme Q10 (CoQ10) supplement could help reduce the side effects of chemotherapy in breast cancer patients. Forty women receiving a specific chemo drug were given either CoQ10 or standard care for twelve weeks. Researchers closely monitored si…

This study tested a new support program for older adults who have finished treatment for breast, colorectal, or prostate cancer. A community health worker met with 30 participants to assess their overall health and provide personalized coaching. The goal was to see if this approa…

This study tested whether taking a Coenzyme Q10 supplement could help protect nerves and reduce side effects like pain, numbness, and fatigue in women receiving paclitaxel chemotherapy for breast cancer. Fifty women were randomly assigned to receive either the supplement along wi…

This study tested whether a gel called Oleogel-S10 helps heal skin irritation caused by radiation therapy in breast cancer patients. Eighteen participants with moderate-to-severe skin reactions applied either the study gel or a standard steroid cream. Researchers measured whether…

This study tested whether a 6-week program of supervised exercise could improve quality of life and reduce fatigue for people with breast or colon cancer. It involved 78 patients, some of whom were also receiving standard cancer treatments like chemotherapy. Researchers compared …

This study aimed to find the best physical therapy approach for women experiencing long-term shoulder pain after breast cancer treatment. Researchers compared three methods: a comprehensive hands-on therapy, targeted shoulder blade exercises, and general shoulder exercises. They …

This study tested whether using e-health tools could help patients better manage pain and anxiety after a breast biopsy. Researchers compared standard follow-up care to two new approaches: regular phone check-ins with a professional or using a smartphone/tablet app to report symp…

This study tested a special helmet that uses low-level laser light to help hair grow back after chemotherapy. It involved 106 women with breast cancer who had recently finished chemo and were experiencing hair loss. Researchers measured hair count, thickness, and quality of life …

This study looked at 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers compared different combinations of surgical and radiation techniques to understand which approaches lead to less scarring and better cosmetic results. The goal was to hel…

This study tested whether giving ketamine during and after breast cancer surgery helps reduce pain and the need for morphine in recovery. It involved 230 women undergoing mastectomy or lumpectomy. Researchers compared pain levels and morphine use in the first 48 hours after surge…

This study tested whether a special mobile phone app could help patients manage their recovery after breast cancer surgery. Researchers compared 60 patients who used the app to those who received standard care. The app provided information, exercises, and tools to track symptoms …

This study looked at a natural breast reconstruction method that uses a woman's own body fat instead of implants. It involved 118 women who had a mastectomy for breast cancer. Researchers wanted to see how well this 'lipomodulin' technique worked, how satisfied women were with th…

This study tested a smartphone app called WeCanManage, designed to help cancer survivors manage long-term disabilities and symptoms after treatment. Twenty survivors of breast, head/neck, or sarcoma cancers tried the app to see if it was easy to use and helpful. The main goal was…

This study looked at whether a traditional mind-body exercise called Shangshou Dao-yin could help breast cancer patients feel better during chemotherapy. Researchers compared 150 patients who either did 20 minutes of daily exercise or received standard care alone. They measured s…

This study looked back at the medical records of 471 women who had breast cancer surgery with immediate reconstruction. It compared a newer, less invasive method using a tiny camera (endoscopic surgery) to the traditional method with a larger cut. The goal was to see which approa…

This study tested if a brief arm massage before chemotherapy could help nurses insert the IV needle more easily. Researchers compared 60 breast cancer patients, giving half a massage before the procedure. They measured how long it took to successfully place the IV, along with the…

This study tested whether a 10-week exercise program delivered through a mobile app is practical and helpful for breast cancer patients undergoing chemotherapy. Researchers worked with 32 patients to see if the app-based exercises could improve shoulder mobility, physical fitness…

This study tested a digital tool designed to help breast cancer patients feel more prepared and less distressed during radiotherapy. 160 patients in Sweden were randomly assigned to either use the new smartphone app alongside standard care or to receive standard care alone. The a…

This study tested whether combining an 8-week mindfulness meditation program with endurance exercise could help women recovering from breast cancer. It involved 100 women who had finished chemotherapy and were undergoing other treatments. Researchers measured whether this combine…

This study compared two different nerve-block techniques for managing pain after breast cancer surgery (mastectomy). Researchers tested the methods on 64 female patients to see which provided better and longer-lasting pain relief with fewer side effects. They found that one speci…

This study tested whether applying a special surgical glue called Ifabond during breast cancer surgery could reduce a common and painful complication called seroma. Seroma is a buildup of fluid under the skin that often requires draining with a needle. The trial involved 104 pati…

This study tested whether a medical spray called Hydrosorb works better than a simple water spray to prevent and treat skin damage from radiation therapy in women with breast cancer. Researchers enrolled 278 women who developed mild to moderate skin redness or irritation during t…

This study tested whether a special exercise program could help improve memory and thinking problems that some women experience after breast cancer chemotherapy. Researchers worked with 37 women who had completed treatment for locally advanced breast cancer and were experiencing …

This study tested whether a mobile health program could help breast cancer patients in underserved areas better manage their pain. The program combined video coaching sessions with a simple phone app to teach pain coping skills. Researchers compared it to a basic health education…

This small pilot study tested whether a collagen-based dietary supplement could reduce joint pain in breast cancer survivors taking hormone therapy. The study followed 30 women experiencing pain from their medication for up to 24 weeks. Researchers measured changes in pain levels…

This study tested whether personalized meal plans encouraging more fish and less red meat could help women manage common symptoms after breast cancer treatment. Researchers worked with 98 women who had finished treatment 1-2 years prior and were experiencing fatigue, pain, depres…

This small study tested whether a non-drug, at-home treatment could help breast cancer patients with insomnia. Twenty participants with stage I-IV breast cancer used a device that delivers gentle electrical stimulation to the ear (called taVNS) nightly for a week. The main goal w…

This study tested whether ear acupuncture (auriculotherapy) could reduce joint and muscle pain caused by common breast cancer medications called aromatase inhibitors. Researchers enrolled 197 postmenopausal women who had experienced this pain for at least three months. Participan…

This study tested if a single nerve-block injection given during mastectomy surgery could reduce both immediate post-surgery pain and the risk of developing long-term chronic pain. Researchers compared two groups of patients: one received the nerve block, and the other did not. T…

This study tested if starting physical therapy and education before breast cancer treatment is practical and helpful. It involved 75 women who were randomly assigned to receive either this early support or standard care. The goal was to see if preparing the body beforehand could …

This study tested if a gentle electrical stimulation applied to a specific point on the wrist during surgery could help prevent nausea and vomiting afterward. It involved 188 women at high risk for these symptoms who were undergoing breast cancer surgery. Participants were random…

This study tested whether self-administered acupressure could reduce joint pain and stiffness in postmenopausal breast cancer patients experiencing these side effects from their aromatase inhibitor medications. Fifty participants were randomly assigned to receive either real or s…

This study tested whether adding ketamine or magnesium sulfate to a standard numbing injection (nerve block) could better control pain after breast cancer surgery. It involved 60 women undergoing surgery and measured how much morphine they needed afterward and how long their pain…

This study tested whether starting a personalized exercise program before breast cancer surgery and continuing it for a year could help with recovery. Thirty women participated, doing exercises to improve shoulder movement, strength, and posture. The goal was to see if this appro…

This study tested whether gentle stretching exercises could help reduce shoulder stiffness, pain, and limited movement that sometimes occur after breast cancer radiation therapy. Researchers worked with 30 women who had completed breast cancer surgery and were starting radiation.…

This study tested different ways to give pain-blocking injections before double mastectomy with reconstruction surgery. Researchers wanted to see which injection method best reduced patients' need for opioid pain medication after surgery. The trial involved over 1,500 women and c…

This study compared two anesthesia methods for patients undergoing breast-conserving surgery with lymph node biopsy. Researchers tested whether a targeted nerve block (PECS block) leads to better recovery quality, less pain, and fewer complications than standard general anesthesi…

This small, completed study tested whether a treatment called extracorporeal shock wave therapy (ESWT) could help breast cancer survivors with axillary web syndrome (AWS). AWS causes painful cords under the arm and limits shoulder movement after surgery. The researchers wanted to…

This study tested three different exercise programs to help women regain arm and shoulder function after breast cancer surgery. 45 women who had surgery with lymph node removal were randomly assigned to either supervised in-person exercises, a telerehabilitation program, or a mob…

This study tested if an 8-week online exercise program could help reduce nerve pain and improve quality of life for breast cancer patients undergoing chemotherapy. 90 participants were randomly assigned to either follow the web-based program or receive usual care. The goal was to…

This study tested whether a patient portal app called MyChart could be used to help breast cancer survivors manage hot flashes, a common and bothersome side effect of treatment. Researchers enrolled 56 patients to see if they could use the app to track their symptoms and test dif…

This study tested whether giving a pain medication called tapentadol before breast cancer surgery could reduce the amount of strong painkillers (like morphine) needed during and after the operation. It involved 70 patients undergoing breast-conserving surgery. Half received the s…

This study tested whether a brief mindfulness program could help women feel less anxious and improve their emotional wellbeing before and after breast cancer surgery. Researchers worked with 42 women who were scheduled for surgery, having them use mindfulness exercises and comple…

This study tested whether giving the drug mirtazapine around the time of surgery could help reduce pain after a mastectomy for breast cancer. It involved 62 women and measured their pain levels, need for morphine, and quality of recovery. The goal was to see if this approach coul…

This study tested whether acupuncture could help reduce hot flashes in breast cancer patients taking hormone-blocking medications. Researchers compared acupuncture treatment against usual care in 84 women who experienced frequent, bothersome hot flashes. The goal was to see if th…

This study tested whether a 6-week online group program could help breast cancer survivors manage chronic pain. Twenty-three participants attended weekly sessions led by different healthcare professionals. The main goal was to see if the program was helpful and practical to run b…

This study tested if a guided breathing technique called 'cardiac coherence,' paired with a hypnosis session, could help reduce anxiety before surgery and improve recovery afterward. It involved 53 adults scheduled for breast or gynecologic cancer surgery. The goal was to see if …

This study tested whether a gentle, hands-on therapy called Craniosacral Therapy (CST) could improve quality of life for women who had finished curative treatment for breast cancer. It involved 102 women and compared two approaches: one-on-one CST sessions and group training in C…

This study tested whether a virtual reality (VR) program could help breast cancer survivors who have memory or concentration problems (often called 'chemo brain') return to or keep their jobs. Twenty-three patients who had finished cancer treatment within the last two years and w…

This study tested whether a home-based yoga program is practical and helpful for breast cancer patients experiencing joint pain from hormone therapy. Researchers worked with 24 patients to see if they could regularly do yoga at home after learning from a therapist. The main goal …

This study tested whether a targeted nerve block, given before surgery, could reduce pain and the need for strong opioid painkillers after breast cancer surgery. It involved 70 women having a specific type of breast cancer operation. Researchers compared the nerve block to standa…

This small, completed pilot study tested a new 12-week occupational therapy program called ActiveHeal EST. It aimed to help breast and prostate cancer survivors build resilience, improve their quality of life, and manage symptoms like pain and fatigue. The program included group …

This study aimed to understand how Mexican American families talk about their risk for common diseases like diabetes, heart disease, and cancer. Researchers worked with 498 adults from multigenerational households to see if sharing personalized risk information with the whole fam…

This study looked at whether the gender of the anesthesiologist, and whether it matches the patient's gender, affects pain and painkiller use after breast cancer surgery. Researchers observed 120 female patients undergoing mastectomy, tracking their pain scores and medication nee…

This study tested a mobile app designed to help Black women with breast cancer learn about nearby clinical trials. Researchers wanted to see if the app was easy to use and if it helped women discuss trials with their doctors. The study involved 80 participants who used the app al…

This early study tested how a common antifungal drug (itraconazole) affects the way the body processes a new experimental breast cancer drug (HRS-8080). Researchers gave both drugs to 16 healthy volunteers to measure drug levels in the blood and check for safety. The goal was to …

This study explored whether breast cancer has a unique smell that could be used for detection. Researchers collected odor samples from the hands, breasts, and tumors of 35 women undergoing breast cancer surgery using a special polymer. They also tested if trained dogs could ident…

This study looked at whether swelling in the arm (lymphedema) after breast cancer treatment is connected to chronic muscle pain. Researchers examined 110 breast cancer survivors to see how common this pain is and how it affects arm movement and daily life. The goal was to better …

This observational study followed 2,424 Russian women with advanced breast cancer to understand how different treatments work in real-world settings. Researchers tracked patients already receiving standard medications like ribociclib, alpelisib, hormone therapy, or chemotherapy a…

This study aimed to find genetic markers in the blood that might predict how well breast cancer patients respond to chemotherapy. Researchers collected blood samples from patients who were receiving standard first-line chemotherapy drugs. The goal was to gather knowledge to help …

This study tested different monthly payment amounts to help breast cancer patients cover the costs of participating in clinical trials. Researchers worked with 33 women already in a breast cancer trial to find what payment amount best reduced their financial stress. They started …

This study tested a new type of CT scanner used during radiation therapy to see if it could produce clearer images. It involved 41 adults receiving radiation for cancers in areas like the head, neck, lung, breast, abdomen, or pelvis. The goal was to see if the improved images cou…

This study looked back at medical records to understand how long Japanese patients with a specific type of advanced breast cancer lived after receiving a two-drug treatment. It involved 42 patients who had previously participated in an earlier clinical trial. The goal was to gath…

This study aims to understand how two different types of radiation therapy affect the heart in breast cancer patients. Researchers followed 172 patients who were already enrolled in a larger radiation comparison trial. They measured heart function and collected blood samples befo…

This study looked at whether some breast cancer patients might safely avoid lymph node removal during surgery. Researchers examined 1,571 patients with specific types of early-stage breast cancer who had no signs of cancer spread to lymph nodes before surgery. The goal was to ide…

This study aims to create a questionnaire specifically designed to measure quality of life for men with breast cancer. Researchers interviewed 65 male patients and healthcare professionals to identify the most important issues affecting their daily lives. The goal is to develop a…

This study looked at why some cancer patients who get a second opinion decide to stay with their original doctor, while others switch to the new doctor. Researchers reviewed the records of 236 patients with breast, pancreatic, or colorectal cancer who got a second opinion at the …

This study aimed to find better ways to monitor breast cancer that has spread to bones. Researchers compared two imaging methods—PET-CT scans and whole-body MRI—to see if they agreed on whether bone tumors were responding to treatment. The study involved 28 patients with breast c…

This study aimed to understand the connection between physical activity and the risk of heart disease in women who have survived breast cancer. Researchers monitored 70 survivors for a week to measure their daily activity levels and exercise capacity. The goal was to gather evide…

This study tested a digital tool designed to give women a clearer picture of their personal breast cancer risk. It combined information from medical records with details provided directly by patients to create a more complete risk profile. The goal was to see if this tool helped …

This study aims to understand if a blue dye used to map lymph nodes during breast cancer surgery affects patients' blood pressure and heart rate while they are under anesthesia. Researchers will observe 220 patients, comparing those who receive the dye to those who do not, to see…

This study aimed to understand how a common chemotherapy drug, 5-Fluorouracil (5-FU), affects small blood vessels, which may explain its known link to heart problems. Researchers compared blood flow in the skin of 62 people across four groups: current 5-FU patients, patients on o…

This study aimed to understand how the emotional skills of young women (45 or younger) with non-metastatic breast cancer and their partners affect how they adjust to the disease and its treatments. Researchers observed 391 couples to see how their emotional awareness and communic…

This study aimed to understand if general anesthesia during breast cancer surgery puts extra stress on the heart for patients who previously received a specific type of chemotherapy called anthracyclines. Researchers measured a blood marker (BNP) linked to heart strain before, du…

This study aimed to find the best schedule for checking heart health in patients receiving trastuzumab, a life-saving breast cancer drug that can sometimes weaken the heart. Researchers compared two different standard monitoring plans in 200 patients with early-stage breast cance…

This study checked if a low-dose vaginal estrogen tablet (Vagifem) is safe for breast cancer survivors taking aromatase inhibitor medications. Researchers measured whether estrogen from the vaginal tablet gets absorbed into the bloodstream, which could potentially affect cancer r…

This study looked back at medical records of 300 breast cancer patients who had rehabilitation after surgery. Researchers used machine learning (a type of AI) to analyze factors like surgery type and complications to build a model. The goal is to predict how long future patients …

This study tested a new automated system to see if it could grow cancer cells from patients with advanced metastatic cancer inside chicken eggs. The goal was to create a faster, cheaper research model to help scientists study cancer and test potential drugs. The study involved 10…

This study aimed to understand how standard chemotherapy for breast cancer affects the body's calcium and vitamin D levels. Researchers followed 146 patients through their treatment to see if they developed high calcium in their urine, a potential side effect. The goal was to gat…

This study looked back at medical records to understand how patients with advanced breast cancer fared when treated with specific drug combinations in regular community oncology clinics. It did not test new treatments but aimed to learn from real-world experiences about treatment…

This study aimed to find better ways to detect when breast cancer spreads to the lining of the brain and spinal cord, a serious complication with poor survival. Researchers collected spinal fluid from 51 patients with suspected spread to test new biological markers. The goal was …

This study aimed to understand if how breast cancer is found—through routine screening or by noticing symptoms—affects a woman's long-term quality of life after treatment. Researchers surveyed nearly 4,500 women in Norway, comparing those with screen-detected cancer, symptom-dete…

This study tested whether a mobile app providing education about HPV and breast cancer could improve women's knowledge and their attitudes toward getting screened. Researchers compared a group of 70 women who used the app to a group that did not. The goal was to see if the app ma…

This study looked back at medical records to understand how common a specific subtype of breast cancer called 'HER2-low' is in the Gulf region. Researchers reviewed records of 517 women with advanced breast cancer to count cases and describe patient experiences. The goal is to ga…

This study tested whether sending text message reminders could get more people to participate in routine cancer screening programs. Researchers compared text messages to standard mail reminders for over 44,000 people eligible for breast or colorectal cancer screening. They measur…

This study aimed to understand how breast cancer treatment affects women's sexual well-being and what kind of education they need about it. Researchers followed 93 women from diagnosis through treatment to learn about their experiences and preferences. The goal was to identify ga…

This small study explored whether analyzing tiny particles (exosomes) in spinal fluid could help diagnose when breast cancer spreads to the lining of the brain and spinal cord (meningitis). Researchers collected spinal fluid from 7 breast cancer patients with suspected spread and…

This study tested two new methods to encourage people at higher risk for hereditary cancers to get recommended genetic testing. Over 800 participants in Michigan were randomly assigned to either use a special website, receive two coaching phone calls, or get standard information.…

This study aimed to understand how physical fitness and daily activity levels relate to diabetes risk in breast cancer survivors taking hormone-blocking therapy. Researchers measured 40 women's fitness, body composition, and activity over two weeks to see connections. The goal wa…

This study looked back at medical records from 298 breast cancer patients to develop a computer model. The model uses patient and tumor information to predict whether a patient will have a complete response to chemotherapy given before surgery. The goal is to help doctors make mo…

This study tested a digital tool designed to help cancer survivors learn about and decide whether to get genetic testing for hereditary cancer risk. Researchers wanted to see if this smart technology was easy to use and if it encouraged more people to get tested. They compared th…

This small pilot study tested whether MRI scans could reliably measure how well breast cancer responds to chemotherapy early in treatment. Researchers enrolled 16 women with breast cancer who were scheduled to receive chemotherapy before surgery. The goal was to see if MRI measur…

This study aimed to create detailed maps showing which areas of skin go numb after different types of pain-blocking injections used during breast cancer surgery. Researchers worked with 36 patients to compare three common nerve block techniques and see how well they covered the s…

This study aimed to understand why certain breast cancer drugs eventually stop working for patients. Researchers analyzed tumor samples from people whose cancer progressed despite treatment with targeted therapies or hormone-blocking drugs. By studying these samples, they hoped t…

This early-stage study aimed to understand how the body absorbs, breaks down, and eliminates an experimental oral drug called SAR439859, which is being developed for breast cancer. Six healthy post-menopausal women received a single, very small dose containing a safe radioactive …

This study looked at whether immune cells found inside breast tumors could help predict how well patients respond to chemotherapy before surgery. Researchers followed 171 women with early breast cancer, analyzing their tumor tissue and blood samples before and after treatment. Th…

This study looked at whether a common breast cancer drug (aromatase inhibitors) causes changes in leg tendons and affects balance, potentially increasing the risk of falls. Researchers compared 76 postmenopausal women with early-stage breast cancer, some taking the drug and some …

This study aimed to understand how breast cancer treatments affect patients' sexual health and quality of life over time. Researchers followed 25 women with non-metastatic breast cancer for one year after starting chemotherapy. They used repeated anonymous questionnaires to track…

This study looked back at hospital records to understand how doctors in Portugal prescribe and adjust specific medications for advanced breast cancer. It analyzed data from over 1,900 patients across 16 hospitals to see how long patients stayed on treatment and how often doses we…

This study tested a new drug called LY3484356 to see how it affects breast cancer tumors before surgery. Researchers gave the drug to 87 postmenopausal women with early-stage, hormone-sensitive breast cancer for a short period before their planned operation. The main goal was to …

This study aimed to understand how a common type of chemotherapy (anthracycline-based) affects the body's ability to control blood pressure and the health of blood vessels. Researchers measured these factors in 60 people with breast cancer or lymphoma, both during treatment and 1…

This study aims to collect detailed information about breast skin to build a more accurate 3D computer model. The model is intended to help surgeons visualize tumors and plan operations for breast cancer patients. Researchers measured skin elasticity and thickness in 200 women an…

This study observed over 2,600 women in Germany with advanced breast cancer to compare how different first-line treatments work in real-world settings. Researchers tracked patients receiving either a combination drug (ribociclib plus hormone therapy), hormone therapy alone, or ch…

This study looked at whether the cancer drug olaparib causes a folic acid (folate) deficiency in patients with advanced ovarian or breast cancer. Researchers wanted to see how often this happens and if giving patients a folic acid vitamin supplement could prevent the deficiency. …

This study looked back at the medical records of 405 Egyptian patients with advanced breast cancer. Its main goal was to find out how many of these patients had a specific subtype called 'HER2-low,' which is a newer way to classify the disease. The results will help doctors under…

This study tested a new online social platform called MammoChat. It aimed to see if letting patients anonymously share their breast screening images and experiences with others could help reduce the stress and anxiety that often comes with these tests. The researchers also used t…

This study aimed to understand if an artificial intelligence (AI) program could be as effective as traditional in-person counseling for genetic testing discussions. It involved 35 women recently diagnosed with breast cancer who did not typically qualify for such testing under sta…

This study looked back at medical records to understand the types of patients who received the drug neratinib for early-stage HER2-positive breast cancer in Europe. It involved 111 patients who had already taken the drug as part of a special access program. The goal was to descri…

This early-stage study tested a new drug called Orialpha (BD-C) in 15 healthy adults to check its safety. The main goal was to find the highest dose people can take without serious side effects. This is the first step in research that could one day lead to a treatment for breast …

This study looked back at the medical records of 1,669 Russian patients with advanced breast cancer that was classified as HER2-negative. The main goal was to see how many of these patients actually had a specific subtype called 'HER2-low' when their tests were re-checked. Resear…

This study aimed to understand how women aged 39-49 react to information about the benefits and risks of mammograms. Researchers surveyed over 600 women to learn why some distrust this information or feel it doesn't apply to them. The goal was to improve how health information is…

This study surveyed 109 breast and prostate cancer patients to understand how often they used vitamins, supplements, and other alternative therapies while undergoing radiation treatment. Researchers asked patients at three different times to see if their use of these therapies ch…

This study tested a new method to understand how the body's immune system recognizes cancer cells in lymph nodes. Researchers worked with 25 patients who had breast cancer or melanoma and were scheduled for lymph node surgery. They measured specific immune cells that target cance…

This study aimed to understand how cancer DNA in the blood changes before, during, and after surgery. Researchers followed 30 patients with breast, prostate, or colon cancer undergoing curative surgery. They measured specific cancer DNA fragments in blood samples to create a base…

This study tested a special monitoring device that measures pain signals in patients under anesthesia during breast cancer surgery. Researchers wanted to see if this device could help determine when nerve blocks (pain-numbing injections) aren't working properly. The goal was to i…

This study tested whether a detailed health survey could help identify and address problems in women aged 70+ after their main breast cancer treatment. Researchers gave the survey results to the patients' doctors and made specialist referrals when needed. The main goal was to see…

This study aimed to understand what breast cancer patients think about physical activity during chemotherapy and whether watching motivational videos from other patients could encourage them to exercise. Researchers surveyed 422 sedentary breast cancer patients about their belief…

This study compared how different hormone therapies for breast cancer affect memory and thinking skills. Researchers followed 44 postmenopausal women with early-stage breast cancer for one year, comparing standard tamoxifen treatment against newer aromatase inhibitors. The goal w…

This study observed how well a specific drug combination (alpelisib plus fulvestrant) worked for Indian patients with a certain type of advanced breast cancer that has a specific genetic mutation (PIK3CA). It also aimed to find out how common this mutation is among Indian patient…

This study aimed to find better ways to screen for breast cancer in women at high genetic risk due to BRCA1 or BRCA2 gene changes. It enrolled 200 women to compare different screening tests, including mammograms, breast MRIs, and a procedure to collect fluid from the breast ducts…

This study tested whether new AI software could help doctors plan radiation therapy more accurately and quickly than traditional manual methods. Researchers compared three ways of outlining organs on CT scans from 500 patients with lung, breast, or esophageal cancer. The goal was…

This study tested whether an online decision support tool could help young women with breast cancer make more informed choices about preserving their fertility before starting cancer treatment. Researchers compared the online tool against the standard practice of receiving inform…

This study aimed to understand how breast cancer affects the quality of life of young women and their life partners. Researchers interviewed 171 couples where the woman was under 45 and had non-metastatic breast cancer. The goal was to create a better questionnaire to measure the…

This study investigated whether the ratio of index to ring finger length is different in women with breast cancer compared to healthy women. Researchers measured the fingers of 132 women (79 with cancer, 53 without) and checked their blood for cancer markers. The goal was to see …

This study tested whether patient navigators could help Black breast and prostate cancer patients complete their radiation therapy. Researchers worked with 30 Black patients to understand what barriers prevent treatment completion and whether navigator support makes a difference.…

This study aimed to understand how chemotherapy given before surgery affects the physical abilities of women with breast cancer. Researchers measured the strength, balance, activity levels, and fatigue of 67 participants before and after their chemotherapy treatment. The goal was…

This study tested a website designed to help primary care doctors have better conversations with women aged 75 and older about whether to continue mammogram screening. It involved 36 doctors and about 90 of their older female patients to see if the tool improved shared decision-m…

This study aimed to see if an educational program could improve knowledge and awareness about breast cancer among women in prison. Researchers worked with 40 incarcerated women who had no history of breast cancer. They measured the women's understanding of symptoms, risks, and se…

This study observed whether giving doctors access to free online prediction tools changed how often they ordered an expensive genetic test (Oncotype DX) for patients with early-stage breast cancer. Researchers tracked 602 patients and surveyed their doctors to understand decision…

This study aimed to understand how to successfully introduce routine breast cancer screening exams in primary care clinics in Soweto, South Africa. Researchers worked with clinic staff, health officials, and local women to identify the main challenges and practical solutions. The…

This study created and tested a short questionnaire to measure how well women accept their breast cancer diagnosis. Researchers gave the 8-question survey to 101 women with breast cancer to see if it reliably measures two things: being open to the reality of the illness and stayi…

This study aimed to understand the nature of memory complaints in people with cancer, specifically brain tumors or breast cancer. Researchers compared 426 participants, including patients and healthy controls, to see if they reported more issues with remembering future plans (pro…

This study tested a training program called KanSurvive-ECHO to help rural primary care doctors provide better follow-up care for people who have finished treatment for breast, colorectal, lung, or prostate cancer. Researchers worked with 20 rural clinics to identify gaps in care …

This study tested whether a brief, culturally sensitive support program led by a nurse practitioner could help breast cancer survivors who were hesitant to start their recommended hormone therapy. The program involved two individual sessions and follow-up questionnaires over 12 w…

The study is designed to compare the clinical benefit following treatment with aromatase inhibitor in combination with metronomic capecitabine versus aromatase inhibitor alone in women with hormone receptor-positive, Her2-negative advanced breast cancer who have not received prio…