BREAST CANCER

This early-phase study tested a personalized vaccine made from a patient's own immune cells, designed to target a protein called HER-2 found on some aggressive breast cancers. The goal was to see if the vaccine was safe and could train the immune system to prevent the cancer from…

This study tested whether Naderin, an immune-boosting drug, could prevent low white blood cell counts in 79 women with breast cancer receiving first-line chemotherapy. Participants either received Naderin alongside chemotherapy or chemotherapy alone. The results showed that only …

This phase 2 trial tested a combination of two drugs—paclitaxel (given intravenously and directly into the abdomen) and oral nilotinib—in 21 adults with cancers that had spread to the lining of the abdomen and could not be surgically removed. The goal was to see if the treatment …

This trial investigates whether structured exercise—either aerobic cycling or resistance training—can improve health-related biomarkers in women with breast cancer undergoing neoadjuvant therapy (chemotherapy or endocrine therapy before surgery). The main focus is on changes in K…

This study tested whether atorvastatin, a cholesterol-lowering drug, can protect the heart in breast cancer patients receiving doxorubicin-based chemotherapy. 44 women with newly diagnosed breast cancer took atorvastatin daily for 3 months alongside their chemo. Researchers measu…

This Phase 1 trial tested an investigational oral drug called CFI-402257 in 52 people with advanced solid tumors, including breast cancer, that had stopped responding to standard treatments. The main goal was to find a safe dose and check how the drug moves through the body. It w…

This early-phase trial tested an experimental drug called KVA12123, given alone or with the immunotherapy Keytruda, in 40 adults with advanced solid tumors (like lung, breast, or colon cancer) that had stopped responding to standard treatments. The main goals were to check safety…

This study tested whether dapagliflozin (Farxiga), a drug used for diabetes and heart failure, can prevent heart damage caused by anthracycline chemotherapy. 94 adults with cancer took either dapagliflozin or a placebo daily for four months alongside their chemo. Researchers meas…

This trial compares a standard mastectomy closure to a technique that adds padding stitches between the skin and chest muscle, aiming to reduce lymphoceles (painful fluid pockets). About 90 women with breast cancer undergoing mastectomy will be randomly assigned to one of the two…

This study looked at whether using a blood test (NTproBNP) to guide heart-protecting medications can safely prevent heart damage in people with breast cancer or lymphoma receiving anthracycline chemotherapy. About 108 adults participated, and researchers measured how many joined,…

This study tested a new oral drug called BGB-43395 in 33 Chinese patients with advanced or metastatic HR+/HER2- breast cancer and other solid tumors. The drug blocks a protein (CDK4) that helps cancer cells grow. The goal was to find a safe dose and see if it can shrink tumors wh…

This trial studies whether breast-conserving surgery (lumpectomy) followed by radiation is a safe and effective option for women aged 40 and older who have two or more breast cancer tumors in the same breast. The goal is to see if this less invasive approach can control the cance…

This study tested a new chemotherapy drug called WH002 against the standard drug paclitaxel in 40 women with HER2-negative breast cancer. Both drugs were given before surgery, followed by two other chemotherapy drugs. The main goal was to compare side effects and how well the tum…

This completed Phase 2 trial tested whether high-dose chemotherapy followed by a stem cell transplant could help people with breast cancer that responds to standard chemo. 203 patients with stage II, III, or IV breast cancer took part. The main goal was to see how long they survi…

This study looked at the safety and effectiveness of a drug called ribociclib combined with hormone therapy for people with a certain type of advanced breast cancer (HR+/HER2-). Researchers collected real-world data from 175 patients in the Middle East to track side effects and h…

This early-phase trial tested a new drug called SRG-514 in 25 people undergoing breast-conserving surgery for breast cancer. The drug was given directly into the area where the tumor was removed. The main goal was to find a safe dose and check for side effects. This is a first st…

This study looked at whether a special needle device (vacuum-assisted biopsy) can completely remove small breast cancers using ultrasound guidance, instead of traditional surgery. 45 women with small, early-stage breast cancers participated. The goal was to see if this less invas…

This early-stage trial tested a new drug called AZD6244 combined with standard chemotherapies in 140 people with advanced solid tumors (breast, colon, lung, melanoma, kidney). The main goal was to see if the combination is safe and tolerable, and to find the best dose. Researcher…

This study tested whether taking oral chemotherapy pills (vinorelbine or capecitabine) along with the targeted drug trastuzumab can help prevent breast cancer from coming back in women with small, HER2-positive tumors that have not spread to lymph nodes. The 182 participants took…

This phase 2 trial tests BB-1701, a drug that targets HER2 on breast cancer cells, in 56 people with advanced breast cancer that is HER2-positive or HER2-low. The study has two parts: first to find the best dose, then to see how well it shrinks tumors. Participants receive the dr…

This pilot study tested a 4-month program that combines weight loss strategies with stress management techniques for Black breast cancer survivors who have obesity and high stress. The program is based on the Diabetes Prevention Program and includes 16 sessions. Researchers measu…

This early-phase study tested a new radioactive drug called 177Lu-CTR-FAPI in 12 people with advanced solid tumors (breast cancer, sarcoma, or thyroid cancer) that had spread and no longer responded to standard treatments. The main goals were to see if the drug is safe and how it…

This pilot study tested a 12-week health behavior program for 50 breast cancer survivors to reduce their risk of heart disease. The program included individual coaching and group sessions focused on exercise and wellness. Researchers measured changes in walking distance and self-…

This completed phase 3 trial tested whether a single, high-dose radiation boost (6 Gy in one session) is as good as the standard 5-session boost (10 Gy total) after whole-breast radiation in 132 breast cancer patients who had breast-conserving surgery. The main goal was to see if…

This study tested an experimental drug called CBX-12 in 69 adults with advanced solid tumors (like ovarian, lung, breast, or colon cancer) that had stopped responding to standard therapies. The main goals were to check the drug's safety, find the best dose, and see if it could sh…

This early-phase study tested a vaccine made from patients' own immune cells to target HER2-positive breast cancer. 31 participants with stage II or III breast cancer received the vaccine alongside standard chemotherapy before surgery. The goal was to see if the vaccine could boo…

This early-stage study tested a custom-made yeast vaccine designed to train the immune system to recognize and attack leftover cancer cells. Five adults with various cancers (like colorectal, breast, or lung) who had completed initial treatment received the vaccine. The goal was …

This study tested a new way to give radiation to people with early-stage breast cancer. Instead of many sessions, patients received just three doses aimed only at the tumor area. The goal was to see if this shorter treatment is safe and works well. 77 patients took part, and the …

This study tested whether cisplatin, a platinum-based chemo, works better than the standard doxorubicin/cyclophosphamide (AC) combo in women with newly diagnosed breast cancer who carry a BRCA mutation. 118 participants received either cisplatin or AC before surgery. The main goa…

This study looked at a shorter course of radiation for women with breast cancer that had spread to nearby lymph nodes after surgery. The goal was to see if this faster treatment was safe and had manageable side effects like arm swelling or shoulder stiffness. 108 women took part,…

This study tested a new surgical method for immediate breast reconstruction after preventive mastectomy in women at high genetic risk for breast cancer. Instead of a scar on the breast, surgeons used a single-port endoscope through the armpit to place the implant under the skin, …

This study tested a combination of the immunotherapy drug atezolizumab and precise radiation (stereotactic radiosurgery) in 6 people with triple-negative breast cancer that had spread to the brain. The goal was to see if the combo could slow or stop the cancer from growing. The t…

This study tested whether a single, precise dose of radiation from a CyberKnife robot could replace multiple standard boost treatments after whole-breast radiation in 29 women with early-stage breast cancer. The goal was to reduce skin side effects like redness and swelling while…

This early-phase study tested a new approach for women with breast cancer that cannot be removed by surgery alone. It combined a short course of high-dose radiation (CyberKnife) with standard chemotherapy drugs. The main goal was to find the safest radiation dose and check for si…

This study tested whether adding the immunotherapy drug atezolizumab to standard chemotherapy (bevacizumab and paclitaxel) helps people with a certain type of advanced breast cancer (HR-positive, HER2-negative). The trial enrolled 281 participants whose cancer had spread or could…

This study tested a type of breast cancer surgery called nipple-sparing mastectomy, where the breast tissue is removed but the nipple and skin are kept. It involved 450 women with early-stage breast cancer who needed a full mastectomy. The goal was to see if this surgery keeps th…

This trial tests an experimental drug called ARV-471, alone or with another drug (palbociclib), in 217 people with advanced ER+/HER2- breast cancer that has stopped responding to standard treatments. The goal is to see if it is safe and can shrink tumors or slow the disease. The …

This completed phase 2 trial enrolled 180 women with ER-positive, HER2-negative advanced or metastatic breast cancer. Researchers compared two different dosing schedules of the targeted drug palbociclib (100 mg daily vs. 125 mg for 3 weeks on, 1 week off) combined with standard h…

This completed trial tested a mobile app called iGAME that gives tips to reduce sitting and encourage healthy habits. Researchers enrolled 48 adults with low back pain, cancer, or depression who were sedentary. The goal was to see if the app could increase physical activity and i…

This study tested a drug called hetrombopag in 60 advanced breast cancer patients whose platelets dropped too low from chemotherapy. The goal was to see if the drug could safely raise platelet counts and prevent treatment delays or dose reductions. Patients took the pill daily wh…

This early-phase trial tested a personalized cancer vaccine (SV-BR-1-GM) combined with an immunotherapy drug (retifanlimab) in 36 people with advanced breast cancer that had stopped responding to standard treatments. The vaccine is made from the patient's own tumor cells and aims…

This study looked at whether taking letrozole, a hormone-blocking drug, could help prevent breast cancer from coming back in women who had already taken tamoxifen for at least 5 years. Over 5,000 women participated, and researchers measured how long they stayed cancer-free. The g…

This study tested a special collagen scaffold placed during breast cancer surgery to help the breast keep its shape after tumor removal. Forty women with early-stage breast cancer took part. The goal was to see if the scaffold safely helps the breast heal and look better, improvi…

This study tested whether giving higher doses of two chemotherapy drugs (epirubicin and docetaxel) along with a drug to boost immune recovery (pegfilgrastim) could help women with advanced or inflammatory breast cancer. 93 women took part. The goal was to see how well the treatme…

This study tested a new two-drug combination (samuraciclib and elacestrant) in 49 adults with a common type of advanced breast cancer (HR+/HER2-). The goal was to find a safe dose and see if it can slow the cancer's growth. Participants had already tried other treatments and thei…

This study tested whether a device that uses focused ultrasound can safely and temporarily open the blood-brain barrier in people with HER2-positive breast cancer that has spread to the brain. Eight participants received the procedure, and researchers checked for side effects and…

This study tested a new drug called giredestrant against the standard drug tamoxifen in 92 premenopausal women with a common type of early breast cancer. Participants took the medication for 15 days before their planned surgery. The goal was to see how well each drug slowed tumor…

This study tested whether adding the drug nintedanib to standard chemotherapy (docetaxel) helps people with advanced HER2-negative breast cancer live longer without their disease getting worse. Fifty-one adults who had already received some treatment took part. The goal was to se…

This early-stage trial tested whether adding pulsed electromagnetic fields (PEMFs) to standard chemotherapy is safe for people with breast cancer. Fourteen participants received the combination before surgery. The main goal was to check for side effects, not to cure the disease. …

This study looked at how often bone marrow suppression occurs in patients with BRCA-mutated, HER2-negative high-risk breast cancer who took LYNPARZA after surgery. It involved 61 participants in Japan. The goal was to monitor side effects in real-world use, not to measure how wel…

This study tested whether giving vitamin D based on a patient's deficiency level works better than a standard dose. 215 breast cancer patients on chemotherapy received either a fixed daily supplement or a tailored dose. The goal was to see which method normalizes vitamin D levels…

This study tested whether injecting a modified herpes virus (T-VEC) directly into tumors, alongside standard chemotherapy before surgery, could better eliminate triple negative breast cancer. The virus is designed to infect and destroy cancer cells while leaving healthy cells alo…

This study tested whether montelukast, an asthma drug, can reduce heart damage caused by doxorubicin chemotherapy in breast cancer patients. Fifty adults with breast cancer were randomly assigned to receive either montelukast or a placebo alongside their treatment. Researchers me…

This study looked at whether a Mediterranean diet and increased physical activity could improve heart health in 150 breast cancer survivors taking hormone therapy. Participants received counseling on diet and exercise over three months. Researchers measured changes in waist size,…

This phase 2 study tested whether adding ganetespib, an experimental drug that blocks a protein called HSP90, to the standard hormone therapy fulvestrant could help people with hormone receptor-positive metastatic breast cancer that has stopped responding to hormone treatment. Th…

This study tested whether adding a low-dose chemotherapy pill (capecitabine) to standard hormone therapy (aromatase inhibitor) helps women with a common type of advanced breast cancer live longer without the disease getting worse. The trial involved 263 women who had not received…

This study tested a new drug, trastuzumab deruxtecan (DS-8201a), against standard treatments for people with advanced HER2-positive breast cancer that had already been treated with T-DM1. The trial included 608 participants whose cancer could not be removed by surgery or had spre…

This study tested whether applying tranexamic acid (TXA) directly into the wound during mastectomy surgery could reduce fluid buildup and infection. 62 women with breast cancer were split into two groups: one received TXA plus a special stitching technique, the other had stitchin…

This study tested a new drug called giredestrant, alone or with triptorelin, against a standard treatment (anastrozole plus triptorelin) in 231 premenopausal women with early-stage, hormone-sensitive breast cancer. The goal was to see how well the drugs slow tumor growth before s…

This phase II trial tested a very strong chemotherapy regimen followed by a stem cell transplant in 41 people with stage IIIB inflammatory breast cancer. The goal was to see if this intense approach could help keep the cancer from coming back and improve survival. Participants re…

This study tested a breast reconstruction method for women who had a mastectomy, with or without radiation. Surgeons first used fat grafting to prepare the chest wall, then placed a breast implant just under the skin (not under the muscle) to reduce pain and animation. The study …

This study tested whether a drug called T-DM1 causes fewer side effects than the standard treatment of paclitaxel plus trastuzumab in people with stage I HER2-positive breast cancer. About 500 participants were randomly assigned to one of the two treatments. The researchers also …

This study tested a specific chemotherapy combination given before surgery for people with triple-negative breast cancer. The goal was to see if the treatment could completely eliminate the cancer from the breast and lymph nodes. 29 participants received the drugs, and the main o…

This study tested whether adding the drug darsilide to standard hormone therapy (exemestane and goserelin) can shrink tumors in premenopausal women with HR-positive, HER2-negative breast cancer. The 119 participants had not responded fully to initial chemotherapy. The main goal w…

This study looked at two different hormone therapy combinations for premenopausal women with a type of breast cancer that grows in response to hormones. Over 2,600 women who had surgery to remove their cancer were randomly assigned to receive either exemestane plus triptorelin or…

This study tested a combination of chemotherapy (paclitaxel) and two targeted antibodies (trastuzumab and pertuzumab) given before mastectomy to 23 women with HER2-positive inflammatory breast cancer. The goal was to see if the treatment could wipe out all cancer in the breast an…

This small pilot study tested whether combining the immunotherapy drug pembrolizumab (Keytruda) with the PARP inhibitor olaparib (Lynparza) can shrink tumors in people with advanced BRCA-mutated breast cancer. Fourteen participants whose cancer had progressed after prior treatmen…

This study tested a combination of three drugs (letrozole, everolimus, and TRC105) given before surgery to postmenopausal women with hormone-receptor-positive, HER2-negative breast cancer. The goal was to see if the combo was safe and could shrink tumors. Fifteen women with stage…

This early-stage trial tested a new oral drug, MSP008-22, in 7 adults with advanced solid tumors (breast, ovarian, prostate, head and neck cancers) that had spread or could not be removed. The main goal was to find a safe dose and check for side effects. This is a first step to s…

This study looked at whether a special care plan led by a geriatrician and a nurse could improve survival and quality of life for older adults (70+) with advanced cancer. 792 patients with breast, colorectal, lung, prostate, bladder, ovarian cancer, or lymphoma took part. The app…

This early-phase trial tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, and lung cancers) that had stopped responding to standard treatments. SNB-101 is a nanoparticle version of SN-38, the active part of a common chemotherapy dru…

This early-phase trial tested a new oral drug called ART4215 in 93 people with advanced or metastatic solid tumors, including breast cancer. The main goals were to find a safe dose and check for side effects when given alone or with other cancer drugs (talazoparib or niraparib). …

This study tested a drug called neratinib, alone or with other medicines, in 140 people with HER2-positive breast cancer that spread to the brain. The goal was to see if the drug could shrink or stabilize brain tumors. Results help doctors understand how well this treatment works…

This study looked at how well the drug ribociclib works in real-world settings for Indian women with a common type of advanced breast cancer (HR+, HER2-). Researchers reviewed medical records of 335 patients treated across 18 sites in India. The goal was to measure how long the d…

This study looked at 720 women with early-stage breast cancer who had a lumpectomy. They were split into two groups: one got standard daily radiation for several weeks, the other got a shorter course of higher-dose radiation. The goal was to see if the shorter treatment works jus…

This study tested a drug called alpelisib combined with hormone therapy (fulvestrant or letrozole) in 383 people with advanced breast cancer that has a specific genetic change (PIK3CA mutation). The goal was to see how many patients were alive without their cancer getting worse a…

This early-phase study tested a new drug called BAT8006 in 216 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and find the best dose for future studies. This is not a cure, but a step toward better control…

This early-stage trial tested an oral drug called JAB-3312 in 40 adults with advanced solid tumors (like lung, colon, or breast cancer) that had stopped responding to standard treatments. The main goals were to find a safe dose and check for side effects. Researchers also looked …

This study tested whether adding the experimental drug samuraciclib to standard hormone therapy (fulvestrant) works better than fulvestrant alone for people with advanced HR+/HER2- breast cancer. The trial enrolled 60 adults whose cancer had worsened despite prior treatment. Rese…

This study tested a new drug called RP903 in 69 people with advanced solid tumors (like ovarian, breast, or cervical cancer) who had run out of standard options. The main goals were to check safety, find the best dose, and see if the drug shrinks tumors. It is an early-phase tria…

This study tested whether adding the immunotherapy drug pembrolizumab to the chemotherapy drug carboplatin works better than carboplatin alone for breast cancer that has returned on the chest wall. The trial included 76 people with either triple-negative or hormone-resistant brea…

This study looked at whether adding a nurse trained in diabetes care to the treatment team helps breast cancer patients with diabetes or prediabetes manage their blood sugar during cancer therapy. Researchers split 74 patients into two groups: one worked with the diabetes nurse, …

This study tested whether adding the antibiotic moxifloxacin to standard chemotherapy improves outcomes for people with operable breast cancer. 559 participants were randomly assigned to receive either moxifloxacin or a placebo alongside their chemo. The main goal was to see if t…

This study tested giving a single, targeted dose of radiation directly to the tumor site during breast cancer surgery, followed by standard radiation. Over 1,100 patients with small tumors were followed for years to see if the cancer came back. The goal was to improve local contr…

This completed study tested whether a shorter, more intense course of radiation (1 week) works as well as the standard 3-week course for women with early breast cancer after lumpectomy. Sixty women were split into two groups to compare side effects, cosmetic results, and cancer c…

This early-phase trial tested a personalized immunotherapy for people with advanced solid tumors. Doctors removed a sample of each patient's tumor, grew the immune cells (TILs) in a lab, and then infused them back along with another drug. The goal was to see if this approach is s…

This early-stage study tested the safety of combining the drug rucaparib with standard radiation therapy in 31 women with triple-negative breast cancer who still had cancer cells after chemotherapy and surgery. The goal was to find a safe dose and see if the combination could be …

This phase 2 trial tested whether adding loperamide (Imodium) and a white blood cell booster (G-CSF) could reduce severe diarrhea and low white blood cell counts caused by the drug Trodelvy in people with advanced breast cancer. Fifty patients with metastatic triple-negative or l…

This study tested whether adding the drug pertuzumab to standard chemotherapy and trastuzumab could help prevent breast cancer from returning after surgery. About 4,800 people with HER2-positive breast cancer took part. The results showed that the three-drug combination improved …

This early-phase trial tested a new way to treat advanced cancers that have spread. It combined a special type of radiation with two immunotherapy drugs (MEDI4736 and tremelimumab) to see if the combination is safe and tolerable. The study included 53 adults with advanced melanom…

This study tested a cancer vaccine called ETBX-011 in 43 people with advanced colorectal, lung, breast, or prostate cancers that produce a protein called CEA. The vaccine uses a modified virus to teach the immune system to attack cancer cells making CEA. The main goals were to ch…

This early-phase study tested a new drug called LY3484356 in 87 postmenopausal women with early-stage, hormone-receptor-positive breast cancer. The goal was to see if the drug is safe and how it affects cancer cells before the participants had surgery. The study lasted up to 2.5 …

This study tested whether adding the drug ribociclib to standard hormone therapy helps slow the growth of advanced breast cancer in Chinese women. About 327 women with a specific type of breast cancer (HR+, HER2-) took part. The main goal was to see how long the cancer stayed und…

This study tested a lower starting dose (400 mg) of the targeted drug ribociclib combined with standard hormone therapy (letrozole or anastrozole) in 376 women with advanced hormone receptor-positive, HER2-negative breast cancer. The goal was to see if the lower dose could contro…

This study looked at 178 Chinese patients with HER2-positive advanced breast cancer who received the drug T-DM1 after earlier treatments failed. Researchers tracked side effects and how long the drug kept the cancer from getting worse. The goal was to see how well T-DM1 works in …

This early-phase study tested whether the heart medication carvedilol could safely protect breast cancer patients from heart damage caused by chemotherapy drugs like doxorubicin and trastuzumab. 68 women with early-stage breast cancer were assigned to either receive carvedilol or…

This phase 2 trial tested whether adding the experimental drug PF-07220060 to the standard hormone therapy letrozole works better than letrozole alone in postmenopausal women with a common type of breast cancer (HR+/HER2-). The 121 participants took the pills for 14 days before t…

This study tested a procedure called radiofrequency ablation, which uses heat from a needle to destroy breast tumors, combined with hormone therapy. It included 21 elderly patients (over 70) who either declined or were not candidates for surgery. The main goal was to see if the c…

This study looked at whether giving arginine supplements to breast cancer patients before surgery could help prevent muscle breakdown and improve recovery. Researchers enrolled 19 women with breast cancer or those having preventive mastectomy. The goal was to see if arginine coul…

This study tested whether a program of regular geriatric checkups, nutrition support, and weekly Tai Chi classes could help women over 70 with breast cancer stay on their hormone therapy. The 12 participants had their blood tested over 3 years to see if they were taking their med…

This study tested a 6-month personalized nutrition and exercise counseling program for breast cancer survivors who are overweight. The program included meetings with a dietitian and a tailored physical activity plan. Researchers wanted to see if participants could lose 10% of the…

This Phase 3 trial tested whether replacing standard taxane chemotherapy (paclitaxel or docetaxel) with eribulin, when combined with pertuzumab and trastuzumab, could control advanced HER2-positive breast cancer just as well while causing less nerve damage. The study enrolled 446…

This early-phase trial tested a new combination of two drugs (ARV-471 and everolimus) in 32 people with a common type of advanced breast cancer (ER+/HER2-). The main goals were to find the safest dose and check for side effects. Researchers also looked at whether the tumors shran…

This early-phase trial tested an experimental drug called FS1502 in 161 people with advanced solid tumors or breast cancer that express HER2. The study had two parts: first, finding a safe dose, and then seeing how well that dose works. The goal was to check safety and early sign…

This Phase 3 trial compares a new hormone therapy pill called elacestrant to standard treatments (fulvestrant or aromatase inhibitors) in 478 people with ER+/HER2- advanced breast cancer that worsened after prior CDK4/6 inhibitor therapy. The study measures how long the cancer st…

This completed Phase 2 trial tested whether adding atorvastatin (a cholesterol-lowering drug) to standard hormone therapy (letrozole or fulvestrant) could improve outcomes in 126 women with advanced, hormone-receptor-positive breast cancer. The main goal was to see if the combina…

This study looked at whether metformin, a common diabetes drug, can reduce the thickening of the uterine lining caused by tamoxifen in postmenopausal breast cancer survivors. Sixty women who had been taking tamoxifen for at least a year were given either metformin or a placebo fo…

This early study tested a combination of a modified herpes virus (T-VEC) and an immunotherapy drug (atezolizumab) in 28 women with aggressive breast cancer that did not fully disappear after standard chemotherapy. The virus was injected directly into tumors to kill cancer cells a…

This pilot study tested high dose rate brachytherapy, a type of internal radiation, in 43 patients with cervical, endometrial, esophageal, prostate, or biliary cancer. The goal was to see if the radiation implants could deliver the planned dose accurately. Participants received b…

This Phase 2 trial tested whether adding enzalutamide (a drug that blocks male hormones) to the standard hormone therapy exemestane could help slow advanced breast cancer in postmenopausal women. The study enrolled 247 participants with hormone receptor-positive, HER2-normal brea…

This completed phase 1 trial tested a radioactive imaging agent called [99mTc]Tc-DB8 in 10 people with prostate or breast cancer. The goal was to see how the agent spreads in the body and whether it can help detect tumors using SPECT scans. Researchers also checked for safety and…

This completed study tested a new radioactive imaging agent called 99mTc-ADAPT6 to see if it can detect HER2 protein in breast cancer tumors using SPECT scans. Sixteen women with primary breast cancer received a single injection, followed by scans over six hours. The goal was to …

This completed phase 1 study tested a new radioactive imaging agent called 99mTc-RM26 in 10 people with prostate or breast cancer. The goal was to see how the agent spreads in the body and whether it can help spot tumors using SPECT scans. Researchers also checked for safety and …

This study tested a new imaging method that uses a radioactive tracer to detect HER2 protein in breast cancer tumors and nearby lymph nodes. 24 women with primary breast cancer received one injection followed by a scan. The goal was to see if the scan results matched standard tis…

This study tested a new imaging agent called 99mTc-ADAPT6 in 30 women with breast cancer that had spread to lymph nodes. The agent is designed to attach to HER2 proteins on cancer cells, allowing doctors to see them on a SPECT scan. The goal was to see if the scan results matched…

This study tested a new radioactive imaging agent that binds to the HER2 protein, which is important for guiding breast cancer treatment. Ten women with known HER2-positive or HER2-negative breast cancer received one injection of the agent, followed by several SPECT scans over 24…

This study tests a special SPECT imaging agent that seeks out a protein called LRRC15, found on many aggressive cancers like pancreatic, breast, lung, and brain tumors. The goal is to see if this scan can help doctors diagnose and stage these cancers more accurately. Healthy volu…

This study tested whether a gene test called MammaPrint can help doctors decide which breast cancer patients need chemotherapy before surgery. The goal is to shrink tumors enough so that patients can have less invasive surgery, like a lumpectomy instead of a mastectomy. The study…

This pilot study tested a new radioactive tracer called 89Zr-DFO*-trastuzumab in 6 people with HER2-positive breast or gastric cancer. The tracer is designed to attach to HER2 proteins on cancer cells and show up on PET scans. Participants received one injection and had up to 4 P…

This study looked at whether a special type of mammogram called contrast-enhanced mammography (CEM) can be used instead of MRI to screen for breast cancer in women at high risk. The study included 615 women who could not have an MRI due to reasons like claustrophobia or implants.…

This study tested a new imaging dye called LS301-IT in 22 women with early-stage breast cancer (DCIS or stage I-II) who were having a partial mastectomy. The dye is injected into a vein before surgery to make cancer cells glow, helping surgeons see and remove them more accurately…

This study aimed to create easy, non-invasive tests using blood and saliva to find markers of certain cancers, like breast and lung cancer. Researchers worked with 250 adults who had these cancers but hadn't started treatment yet. The goal was to improve early detection and monit…

This study tested whether specially trained dogs can identify breast, lung, prostate, or colorectal cancer by sniffing breath samples collected on masks. Over 1,300 people provided breath samples before their regular cancer screening or biopsy. The dogs' results were compared to …

This study tested a new way to tell breast cancer types apart using a special ultrasound, instead of a tissue biopsy. Researchers looked at blood vessel patterns in tumors from 94 patients and built a tool to predict whether the cancer was luminal or non-luminal. The goal is to h…

This study tested whether using contrast-enhanced mammography to guide breast biopsies is more accurate than the standard X-ray-guided method for suspicious calcifications. About 184 women with suspicious calcifications (BIRADS R3-R5) were randomly assigned to one of the two biop…

This study looked at whether MRI can more accurately measure the size of ductal carcinoma in situ (a very early form of breast cancer) compared to standard mammography. Forty women with the condition had MRI scans before surgery. Researchers then compared the MRI results with the…

This study tested whether a newer type of PET scan (68Ga-FAPI) can better predict if breast cancer has been fully eliminated by chemotherapy compared to standard PET scans (18F-FDG) and MRI. Twenty-seven women with breast cancer had all three scans before and after chemotherapy, …

This study tested a new imaging technique called restriction spectrum imaging (RSI) to see if it can find breast cancer as well as standard breast MRI. About 460 women who were getting routine breast cancer screening took part. The goal was to compare how accurate RSI is versus c…

This completed study tested a special dye called TTP-ICG that sticks to breast cancer cells. After removing tissue, doctors soaked it in the dye and used a special camera to see if cancer cells were left at the edges or in lymph nodes. The goal was to help surgeons know right awa…

This study looked at whether a small, portable ultrasound device can accurately tell the difference between benign (non-cancerous) and malignant (cancerous) breast lumps in women who had a positive clinical breast exam. Researchers tested the device on 150 women, using standard i…

This large study tested whether artificial intelligence (AI) can make mammography screening better. Over 100,000 women were randomly assigned to have their mammograms read with AI assistance or by the usual two radiologists. The goal was to see if AI could catch more cancers, red…

This study tested a new, noninvasive method called SAVE to help classify breast masses as benign or malignant. Researchers at Mayo Clinic enrolled 266 women with breast lesions to see how well the SAVE method could tell cancerous from non-cancerous masses. The goal is to provide …

This study tested whether a special PET scan (called 18F-DOPA PET-CT) can find brain metastases as well as or better than standard MRI in people with lung cancer, breast cancer, or melanoma. 32 adults with untreated brain metastases took part. The goal was to see if this PET meth…

This study compared two MRI contrast agents, Dotarem and Gadavist, in 300 women undergoing breast MRI. The goal was to see if Dotarem is as effective as Gadavist at enhancing breast lesions for clearer images. Participants were randomly assigned to receive one of the two agents, …

This study compared contrast-enhanced mammography (CESM) and magnetic resonance imaging (MRI) for diagnosing suspicious breast lesions in 231 women. Both imaging methods were evaluated against biopsy or surgery results to see which is more accurate. The goal is to determine if CE…

This study tested whether a contrast-enhanced mammogram (angiomammography) can predict if breast cancer will fully disappear after chemotherapy. 67 women with breast cancer had imaging after two rounds of chemo. The goal was to see if this method could identify non-responders ear…

This study tested an artificial intelligence (AI) tool called Carebot AI MMG to see how well it can find breast lesions and measure breast density from mammograms. Researchers compared the AI's accuracy to that of human doctors using 122 mammogram studies. The goal was to see if …

This study looked at how many tissue samples are needed when doing a special type of breast biopsy called contrast-enhanced stereotactic biopsy (CESB). The biopsy is used for breast lesions that only show up on contrast-enhanced mammography. Researchers studied 77 women to find t…

This study looked at whether testing for certain gene changes (methylation) can help doctors tell if a breast lesion is cancerous or not. 301 women with suspicious breast lumps had standard biopsies plus extra gene testing. The goal was to see if the gene test could improve diagn…

This study tested whether adding two special ultrasound techniques—elastography and contrast-enhanced ultrasound—can better detect breast cancer spread to underarm lymph nodes. Researchers studied 180 women with breast cancer to see if these extra scans improve accuracy compared …

This study tested an AI system called Carebot AI MMG to see if it can detect breast cancer from mammograms as accurately as human radiologists. Researchers looked at 222 past mammograms from four screening centers. The AI classified each exam as low, medium, or high risk, and its…

This study tested whether a fast (abbreviated) breast MRI can detect cancers that mammograms miss in women who have already been treated for breast cancer with lumpectomy and radiation. Researchers recruited 184 women who had a normal 3D mammogram and gave them a quick MRI. The g…

This study tested a new blood test (liquid biopsy) that looks for cancer DNA in the blood of 30 women with advanced ER+/HER2- breast cancer. The goal was to see if the test can accurately find cancer mutations without needing a traditional tissue biopsy. The results will help doc…

This study tested a new handheld gamma camera (CarolIReS) in 110 breast cancer patients to see if it could find sentinel lymph nodes that standard methods miss. The camera was used before and during surgery to guide removal and check if any nodes were left behind. The goal was to…

This large trial compared two breast cancer screening methods in nearly 27,000 women aged 45-74. One group received standard 2D mammography plus a newer 3D technique called digital breast tomosynthesis, while the other got only standard mammography. Researchers wanted to see if t…

This study tested whether an AI program called CadAI-B Dx helps doctors better detect breast cancer on ultrasound images. Researchers compared how 16 doctors performed with and without the AI's help, using 797 cases (350 with cancer, 447 benign). The goal was to see if the AI imp…

This study tested a new microwave imaging device called Wavelia #2 to see if it can detect and measure breast cancers and benign lumps. 73 women with breast abnormalities larger than 1 cm were scanned. The goal was to see how well the device finds lesions and tells cancerous from…

This study tested a device called PointCheck that uses light to check for severe neutropenia (low white blood cells) in cancer patients without needing a blood sample. Researchers enrolled 81 adults with blood or breast cancers who were receiving chemotherapy. The main goal was t…

This study looked at whether an MRI can detect breast cancer in women who have abnormal nipple discharge but normal mammograms and ultrasounds. 70 women with single-pore, non-milky, non-green discharge were given an MRI. The goal was to see how often a normal MRI meant no cancer …

This study tested a new ultrasound-based imaging method called Nonlinear Elasticity Mapping (NEM) to help tell apart benign and cancerous breast lumps. Researchers measured how breast tissue stretches and compresses, looking for patterns that match cancer. 172 women with breast f…

This study tested whether a fluorescent dye called indocyanine green (ICG) can help surgeons locate small, non-palpable breast tumors during surgery. Ten women with early-stage breast cancer received both the dye and a standard radioactive seed, and doctors compared how well each…

This study tested a new imaging method that combines ultrasound with light to better tell if a breast lump is cancer or not. The goal was to see if this approach could safely reduce the number of women who need a needle biopsy for a benign (non-cancerous) lump. About 298 women wi…

This study explored whether breast cancer has a unique smell that can be detected. Researchers used a special polymer (Sorbstar®) and trained dogs to sniff samples from 35 women before and after tumor removal. The goal was to see if a distinct scent signature exists, which could …

This study followed 40 women at high genetic risk for ovarian cancer due to BRCA mutations or strong family history. One group chose to have their ovaries and fallopian tubes removed to prevent cancer, while the other group opted for regular CA-125 blood tests every 3 months to c…

This study looked at whether adding physical therapy to educational materials could prevent lymphedema (arm swelling) in women treated for breast cancer. Over 1,000 women who had lymph nodes removed were randomly assigned to receive either education alone or education plus a pers…

This small pilot study tested whether an ice plant cream could prevent hand-foot syndrome (pain, redness, peeling on hands and feet) in 15 breast cancer patients receiving doxorubicin or docetaxel chemotherapy. The main goal was to see if a larger study is possible, not to prove …

This early-phase study tested whether losartan, a common blood pressure medication, could prevent early heart damage caused by radiation therapy in breast cancer patients. Five women with left-sided breast cancer who were scheduled for radiation took losartan. Researchers used he…

This study looked at whether teaching women simple self-massage and stretching exercises before and after breast cancer surgery could prevent long-term pain. 143 women took part. Half received standard care, and the other half also attended workshops to learn these techniques and…

This study looked at whether a personalized exercise program, started before breast cancer surgery and continued for 12 months after, could prevent lymphedema (arm swelling) and improve recovery. Forty women scheduled for breast cancer surgery took part. They received structured …

This study tested two culturally tailored programs to encourage breast cancer screening among 323 White Mountain Apache women. One group received a culturally relevant education module (CARE), while the other also got access to an Apache women's health coach. The main goal was to…

This study tested whether taking alpha lipoic acid, a common antioxidant, could prevent heart damage caused by the chemotherapy drug doxorubicin in breast cancer patients. 80 women starting their first round of doxorubicin-containing chemotherapy were enrolled. Researchers measur…

This study tested whether injecting a local anesthetic called ropivacaine into the surgical area could prevent chronic breast pain after breast cancer surgery. Researchers compared the anesthetic to a placebo (salt water) in 260 patients. The goal was to see if fewer people had p…

This trial tests whether a four-week mindfulness program, delivered by a nurse, can reduce psychological distress and increase hope and mindfulness in women with breast cancer receiving radiotherapy. One hundred women who had mastectomy and are now undergoing radiotherapy are ran…

This study tests whether a 6-week online mindfulness program can lower stress, anxiety, and other side effects in women with breast cancer who are about to start chemotherapy. Two hundred participants will be randomly assigned to either the online mindfulness sessions or no extra…

This study tested whether technology-based rehabilitation (telerehabilitation or a mobile app) could improve arm and shoulder function after breast cancer surgery, compared to standard physiotherapy. 45 women who had surgery with lymph node removal participated. The goal was to s…

This study tested whether a mobile app designed for cancer survivors can help them exercise more after finishing treatment. 132 breast cancer survivors used either the app or received standard exercise guidelines for 12 weeks. The goal was to see if the app increased exercise, re…

This Phase 3 trial tested whether Nuvastatic, a plant extract, can reduce cancer-related fatigue in 180 women with breast cancer undergoing chemotherapy. Participants took Nuvastatic or a placebo three times daily for three chemo cycles. The study measured fatigue levels and qual…

This study looked at whether e-health tools—like a phone call from a specialist or a self-report app—can help manage pain and anxiety after a breast biopsy. About 193 women took part. The goal was to see if these check-ins lead to less pain and better well-being compared to stand…

This study tested a technique called graded motor imagery to help women with chronic shoulder pain after mastectomy. The approach uses left/right judgment tasks, imagined movements, and mirror therapy to retrain the brain's perception of the shoulder. Fifty-four women participate…

This study tested whether EMDR (a therapy using guided eye movements) could help reduce anxiety and depression in women with breast cancer. Fifteen women who had mastectomy for invasive breast cancer received up to 8 sessions of EMDR during their cancer treatment. The main goal w…

This study looked at whether a 30-minute myofascial massage can reduce shoulder stiffness and improve blood flow in breast cancer survivors who have myofascial pain. Twenty-one women who had completed breast cancer treatment 3 months to 2 years earlier received one massage sessio…

This study tested whether a noninvasive device that gently stimulates a nerve in the ear (taVNS) could help breast cancer patients with insomnia. Twenty adults with stage I-IV breast cancer who had trouble sleeping for at least three months took part. The main goal was to see if …

This study tested whether a 20-minute virtual reality session before a planning CT scan could lower anxiety in 256 breast or pelvic cancer patients starting radiotherapy. Patients were randomly assigned to either the VR session or usual care. The goal was to see if VR could reduc…

This study tested whether an 8-week online positive psychology program could help women who finished breast cancer treatment feel less afraid of the cancer coming back. 38 women took part, with half attending weekly group sessions on gratitude, optimism, and savoring good moments…

This study tests whether PG2, a compound from the astragalus root, can reduce fatigue and low white blood cell counts caused by chemotherapy in women with stage II or III breast cancer. Participants receive either PG2 or a placebo alongside their standard chemotherapy. The goal i…

This study compared two ways to manage pain during breast cancer surgery: a nerve block (erector spinae plane block) and a lidocaine drip given through a vein. Researchers measured inflammation markers and pain levels in 40 women undergoing surgery. The goal was to see which meth…

This study tested whether a 12-week music listening program could help breast cancer patients with memory and thinking problems caused by chemotherapy. 90 women took part, with half listening to self-chosen music daily for at least 20 minutes plus usual care, and the other half r…

This study tested whether a structured educational program could help women with breast cancer improve their sexual function and better follow their medication plans. Sixty-two women took part, attending sessions about their disease, treatments, side effects, and the importance o…

This study tested whether professional socio-aesthetics (specialized beauty and well-being care) can improve quality of life, reduce pain, and ease anxiety in adults undergoing chemotherapy for lung, breast, colon, or prostate cancer. 400 participants were randomly assigned to re…

This study tested whether a nerve block (PECS II) or local anesthesia works better for pain after breast cancer surgery, without using opioids. 124 women undergoing breast surgery were randomly assigned to receive one of the two methods. Researchers measured pain, nausea, and opi…

This study looked at whether music therapy can lower anxiety in women with early-stage breast cancer during chemotherapy. Twenty-seven patients took part, with some receiving music therapy sessions while others did not. Researchers measured anxiety levels before and after each ch…

This study tested three ways of giving the steroid dexamethasone to prevent allergic reactions from the chemotherapy drug paclitaxel in 90 women with breast or gynecologic cancer. One group took oral dexamethasone the night before and morning of treatment, another got it intraven…

This study looked at whether fencing can help women who had surgery for breast cancer. Thirty patients took fencing lessons and were checked for improvements in arm function and quality of life. The results were encouraging, suggesting fencing may be a fun way to aid recovery.

This pilot study tested whether a self-management program combining exercise classes and group discussions could relieve joint pain caused by aromatase inhibitors (AI) in older breast cancer survivors. Twelve women aged 60 and older who were starting AI medication took part. The …

This study tested whether wearing special light glasses for 30 minutes each morning could help breast cancer patients feel less tired, sleep better, and think more clearly during treatment. The trial included 260 women with early-stage breast cancer, plus a healthy comparison gro…

This study looked at whether walking, with or without a grounding stick, can reduce pain, fatigue, and improve sleep in women with breast cancer. Fifty-five women who were on chemotherapy took part. They walked for 30 minutes at least three times a week for eight weeks. The goal …

This study tested three different ways to prescribe and monitor resistance training intensity in 61 breast cancer survivors who had finished treatment. The goal was to see which method best improves muscle strength, body composition, and psychological well-being. Participants per…

This study tested whether standing on a low-intensity vibrating platform for 10 minutes twice a day for 12 months could improve muscle function and reduce pain in early-stage breast cancer survivors starting aromatase inhibitor therapy. 72 women who did not exercise regularly wer…

This study looked at whether a nurse-led coaching program can help women who had breast reconstruction after breast cancer. 58 women took part; half got coaching sessions over 12 weeks, and half got standard care. The goal was to see if coaching improved their ability to care for…

This study tested whether taking a daily probiotic supplement could reduce inflammation caused by chemotherapy or immunotherapy in women with breast cancer. Sixty women took either a probiotic or a placebo for eight weeks while receiving treatment. Researchers measured changes in…

This study looked at whether adding magnesium sulfate to a standard numbing medicine (bupivacaine) in a nerve block could improve pain control after a mastectomy. Seventy women having breast cancer surgery received either the standard nerve block or one with added magnesium. The …

This study tested whether a simple writing exercise about personal values could reduce physical symptoms and stress, and improve medication adherence in 250 breast cancer patients taking aromatase inhibitors. Participants wrote one essay per month for six months, either about the…

This study looked at whether a stress management program called Pythagorean Self-Awareness Intervention could help breast cancer survivors. 120 women who had finished their main cancer treatments (but could still be on hormone therapy) took part. The researchers measured stress, …

This study tested a hybrid (online and in-person) group education program based on psychodynamic nursing theory for women who had a mastectomy. The goal was to see if it could improve how they value their bodies, reduce anxiety about their appearance, and enhance their sexual qua…

This study tested whether giving monthly reimbursements to women with breast cancer in clinical trials could reduce their financial hardship. Thirty-nine participants received payments for trial-related expenses, and researchers tracked how many completed the study and surveys. T…

This study tested whether Daflon, a medication usually used for vein problems, can reduce seroma — a common fluid buildup after breast cancer surgery. 190 patients took Daflon or a placebo for four weeks after surgery. The goal was to see if it lowers the chance of seroma forming…

This study looked at whether a program of exercise before surgery and a special recovery plan after surgery could help women leave the hospital sooner after a mastectomy. Twenty-four women with breast cancer took part. The program included walking, cycling, and strength exercises…

This study looked at whether adding nerve mobilization (gentle stretching exercises for nerves) to early physical therapy can reduce long-term shoulder disability in women after breast cancer surgery. 140 women who had surgery for breast cancer took part. The results help underst…

This study looked at whether taking omega-3 fatty acid supplements can reduce joint pain and stiffness caused by aromatase inhibitors, a common hormone therapy for breast cancer. 77 postmenopausal women with early-stage breast cancer or at high risk took omega-3 supplements soon …

This study looked at whether it's possible to test a program that combines different approaches to help breast cancer survivors with sexual health issues. 18 women who had finished their main cancer treatment took part. The goal was to see if women would join, stay, and follow th…

This study tested whether cognitive education activities could help breast cancer patients who experience memory, attention, and thinking problems after chemotherapy, often called 'chemobrain'. 108 patients took part. The activities were designed to support memory, attention, and…

This study tested short, digital exercises (called micro-interventions) designed to reduce distress and improve well-being in breast cancer survivors. 120 women who had been diagnosed with early-stage breast cancer in the past 5 years and had mild-to-moderate anxiety or depressio…

This study tested whether wearing special cold caps (Penguin caps) during chemotherapy could prevent or reduce hair loss in people with early-stage breast cancer. Twelve participants used the caps while getting one of four common chemo regimens. The goal was to see if at least ha…

This study looked at whether taking fat from one part of the body and moving it to a breast that was damaged by radiation can help the tissue heal. Ten women who had radiation for breast cancer took part. The goal was to see if this fat transfer could make the skin softer and les…

This study looked at whether a special vacuum-assisted wound dressing (ciNPWT) helps reduce complications after breast reconstruction surgery using the patient's own tissue. Researchers reviewed records of 253 women who had this surgery between 2012 and 2025. They compared those …

This study tested a silver-plated wound dressing (Silverlon) in 17 breast cancer patients receiving radiation therapy. The goal was to see if the dressing could reduce the severity of acute radiation dermatitis, a common skin reaction that causes redness, peeling, and pain. Patie…

This study tested whether an online exercise and education program could help cancer patients and survivors feel better during the COVID-19 pandemic. Thirty adults with metastatic breast or gynecological cancer, or breast cancer survivors, took part. The program aimed to reduce f…

This study tested whether a gentle arm massage with sesame-lavender oil can reduce acute pain and anxiety in women after mastectomy surgery. 90 women were randomly assigned to receive massage with either sesame-lavender oil, plain sesame oil, or paraffin oil (a placebo). The goal…

This study tested whether Coenzyme Q10, a dietary supplement, can reduce nerve damage, fatigue, and pain in women with newly diagnosed breast cancer receiving paclitaxel chemotherapy. Fifty women took either CoQ10 plus chemotherapy or chemotherapy alone for twelve weeks. Research…

This study tested a program called Maximizing Energy to help women who finished breast cancer treatment manage their fatigue. Fifteen women took part, either in the program or a general health education group, over six online sessions. Researchers checked if women stayed in the s…

This completed study tested a culturally adapted program to help breast cancer patients manage joint and muscle pain caused by hormone therapy. 289 women on aromatase inhibitors received either the tailored program (health education, monitoring, and nursing guidance) or standard …

This study looked at whether mild to moderate aerobic exercise, done three times a week for three weeks, could improve quality of life and blood levels of zinc, copper, and iron in 28 post-menopausal women who had radiotherapy for breast cancer. The goal was to see if a simple ex…

This pilot study looked at whether a 12-week supervised exercise program could improve body composition and physical function in 62 breast cancer patients. Participants exercised 2-3 times per week for 90 minutes. The study measured changes in fat mass, lean mass, bone density, a…

This study tested whether adding magnesium sulfate to a standard nerve block (erector spinae plane block) reduces pain and the need for morphine after a mastectomy. Sixty women scheduled for breast cancer surgery took part. The main goal was to see how much morphine they needed i…

This study tested whether a personalized telephone-based weight loss program could help reduce fatigue in overweight or obese breast cancer survivors. 220 participants who had finished active treatment for early-stage breast cancer were enrolled. The program provided motivational…

This study tested whether using virtual reality (VR) and music during chemotherapy sessions is practical and helpful for breast cancer patients. Sixty patients were offered VR headsets with calming music and videos while receiving chemo. The goal was to see if patients would use …

This study compared two types of nipple-sparing mastectomy for breast cancer: one done with a robot and the other with traditional open surgery. 82 women took part, and the main goal was to see which approach led to higher patient satisfaction. The trial also looked at recovery t…

This study tested whether a digital physiotherapy platform (Trak) helps women recover shoulder movement better than standard paper-based exercises after lymph node removal for breast cancer. Forty women participated in a 4-week home program. Researchers measured shoulder mobility…

This study looked at whether mindfulness exercises can lower stress and improve communication between patients with liver disease and their doctors. 56 adults took part, answering surveys about their stress, anxiety, and how well they felt they could share decisions with their he…

This study tested a home-use helmet that shines low-level light on the scalp to help hair regrow after chemotherapy. 106 women with breast cancer who had just finished chemo used the device three times a week for four weeks. Researchers measured hair count and width, and tracked …

This study tested whether personalized remote exercise coaching, using a digital platform and a connected watch, could improve quality of life in 824 breast cancer survivors. Participants were randomly assigned to receive either the coaching or standard advice. The study measured…

This study tested a web-based dance movement therapy program for women with breast cancer undergoing chemotherapy. 67 participants were asked to dance at home three times a week for at least 70 minutes per session. Researchers measured changes in alexithymia (difficulty identifyi…

This study tested two different doses of lidocaine given through an IV to women who had nerve pain after mastectomy for breast cancer. Thirty women took part, and researchers measured how the pain felt (like burning or stinging) using a special scale. The goal was to see if lidoc…

This study tested whether a technique called ischemic preconditioning, which is used to protect organs during transplants, could reduce fat tissue damage after breast reconstruction surgery. 18 women who had breast reconstruction using their own belly fat were included. The appro…

This study looked at whether an 8-week virtual program focused on healthy eating and exercise could reduce stress and improve quality of life for breast cancer survivors. Twenty-two adults who had been diagnosed with breast cancer took part in weekly 90-minute online sessions. Re…

This study tested a group video app that guides breast cancer survivors through yogic breathing exercises at home. The goal was to see if the app helps reduce stress and other long-term side effects from cancer treatment. Forty survivors who finished radiation therapy within the …

This study tested whether a specific meditation technique, Twin Hearts Meditation, could reduce nausea and vomiting caused by chemotherapy in women with breast cancer. 102 women were split into two groups: one practiced meditation for 30 minutes at least three times a week, while…

This study tested whether a 7-day supervised fast (max 350 calories per day) could reduce muscle and joint pain in 54 breast cancer patients taking aromatase inhibitors. The goal was to see if fasting is feasible and improves physical well-being and quality of life. Researchers a…

This study tested whether a combination of physiotherapy techniques—including dry needling, nerve gliding exercises, and scapula strengthening—works better than exercise alone for women with ongoing shoulder pain after breast cancer treatment. Ninety women were randomly assigned …

This study looked at 60 women having breast cancer surgery (mastectomy). Doctors gave them a nerve block with either bupivacaine alone or bupivacaine plus magnesium sulfate to see which provided longer pain relief after surgery. The goal was to find a better way to manage post-op…

This study tested whether acupuncture can reduce hot flashes in women with hormone-positive breast cancer who are on hormonal therapy. 84 participants were randomly assigned to receive either acupuncture or usual care. The main goal was to see if acupuncture lowered hot flash sco…

This study tested three different nerve block methods to manage pain after a double mastectomy with immediate reconstruction. Over 1,500 women received either a paravertebral block, a serratus+PECS-1 block, or a combination. The goal was to see which approach reduces the need for…

This study tested whether a mobile app helps cancer patients undergoing chemotherapy or radiation therapy report their symptoms more effectively. Over 200 participants used the app to track side effects for 8 weeks. The goal was to see if the app improves how patients recognize a…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study looked at whether giving a tiny amount of the opioid remifentanil right after surgery could prevent a condition called opioid-induced hyperalgesia, where opioids actually make pain worse. It involved 41 women with breast cancer having breast surgery under total intrave…

This study compared two types of nerve blocks—serratus posterior superior intercostal plane block and thoracic paravertebral block—for pain relief after mastectomy. Sixty women received one of the blocks along with standard painkillers. Researchers measured pain scores and opioid…

This study tested a brief, nurse-led videoconference program designed to help breast cancer survivors who were hesitant or delayed in starting recommended hormone therapy. The program aimed to address cultural and personal concerns. Researchers measured how many people enrolled, …

This study tested whether a web-based exercise program could reduce nerve pain and improve quality of life in breast cancer patients receiving chemotherapy. 90 patients with stage II-III breast cancer and neuropathy symptoms took part. The program was guided by a physiotherapist …

This study looked at whether giving a lower dose of the steroid dexamethasone before the chemotherapy drug docetaxel can prevent allergic reactions with fewer side effects. The standard high dose can cause problems like high blood sugar, mood changes, and weakened immunity. Resea…

This study tested a program to help young couples cope with reproductive and sexual health problems after breast or gynecologic cancer. 158 survivors and their partners took part in a videoconference intervention. The goal was to reduce distress and improve communication about fe…

This study looked at side effects from a special radiotherapy technique called simultaneous integrated boost (SIB) given after breast-conserving surgery for breast cancer. 93 women were followed to see how well they tolerated the treatment. The goal was to compare side effects wi…

This pilot study looked at whether a supervised or distance-supervised brisk walking program could help manage fatigue in breast cancer patients currently on hormone therapy. Seventeen women who had completed chemotherapy and/or radiation took part in a 6-week program, walking tw…

This study tested whether adding dexmedetomidine (a sedative) to a standard numbing medicine (bupivacaine) in a chest nerve block could improve pain control after breast cancer surgery. Sixty women received either the standard block or the block with added dexmedetomidine. The ma…

This study tested a cognitive training program to help breast cancer patients manage 'chemobrain'—memory and thinking problems caused by chemotherapy. Fifty women with newly diagnosed breast cancer took part, with half receiving the training plus educational materials, and the ot…

This study looked at breast reconstruction using only a patient's own fat (lipomodulin) after mastectomy for breast cancer. Researchers wanted to see how often the procedure works, how the breast looks afterward, and how it affects quality of life. The study included 118 women wh…

This study tested a virtual reality program to help breast cancer patients who have memory or concentration problems after treatment. 23 patients used the VR program for 10-15 minutes each week for 6 weeks. The goal was to see if patients would stick with the program and if it co…

This study tested whether a mobile app exercise program is practical and helpful for 32 women with breast cancer undergoing chemotherapy. The program included guided exercises and education to improve arm function, fitness, and quality of life. Results will show if this approach …

This study tested whether a combination of slow, guided breathing (called cardiac coherence) and a hypnosis session could help women feel less anxious before breast or gynecologic cancer surgery. Fifty-three women participated, practicing the breathing technique several times a d…

This study tested two types of nerve blocks to control pain after breast cancer surgery. 32 women received one of two ultrasound-guided injections before surgery. The serratus anterior plane block provided better pain relief, lasted longer, and caused fewer side effects like naus…

This study tested whether a yoga program done at home and in group sessions is practical for breast cancer patients on hormone therapy who have joint pain. 24 patients were asked to follow daily home yoga and attend 6 sessions with a therapist. The goal was to see if patients wou…

This study tested whether adding ketamine or magnesium sulfate to a standard numbing medicine (levobupivacaine) can improve pain control after breast cancer surgery. Sixty adults undergoing mastectomy received one of the two add-ons via a nerve block. The main goal was to see if …

This study tested two methods for marking non-palpable breast tumors before surgery: a tiny iodine seed versus a standard metal wire. 350 women with early-stage breast cancer took part. The goal was to see if the seed method leads to cleaner surgical margins, potentially reducing…

This study looked at whether adding verbal cues from a therapist during exercise helps breast cancer survivors on radiation therapy. 34 women did a 12-week exercise program with or without verbal guidance. Researchers measured shoulder movement, fatigue, and stress levels to see …

This study tested whether adding a single dose of the muscle relaxant tizanidine to a nerve block (ESP block) improves pain control after mastectomy. 90 patients were randomly assigned to receive either the nerve block alone or the nerve block plus tizanidine before surgery. The …

This study tested two different nerve blocks—PECS II and SPSIP—to see which provides better pain relief after breast cancer surgery. 118 women received one of the blocks before surgery, and researchers measured how much opioid painkiller they needed in the first 24 hours. The goa…

This study tested a mobile app designed to help women manage lymphedema (arm swelling) and improve their quality of life after breast cancer surgery. Sixty women who had breast-conserving surgery or lymph node removal used the app for education, exercise guidance, and symptom tra…

This study tested two different nerve block techniques to manage pain after breast cancer surgery. Sixty women received either an erector spinae plane block or a combination of serratus anterior and pecto-intercostal fascial plane blocks. Researchers measured how much morphine ea…

This study tested a shorter course of radiation therapy for people with early-stage breast cancer after lumpectomy. The goal was to see if this approach causes fewer skin side effects. 35 participants received the treatment, and researchers measured how many developed moderate to…

This study tested a radiation method called multi-beam IMRT in 100 women with breast cancer who had implant reconstructions after mastectomy. The goal was to see if using 8-12 small radiation beams instead of the standard 2-5 could reduce implant failure and side effects. Results…

This pilot study tested an online program called THRIVE, based on Positive Affect Training, to help breast cancer survivors feel better about taking their anti-hormonal medication. The goal was to see if the program was acceptable and feasible for women who struggle with side eff…

This study looked at whether taking mirtazapine, a common antidepressant, before and after mastectomy surgery can reduce pain and the need for strong painkillers. 62 women scheduled for mastectomy were given either mirtazapine or a placebo daily for two weeks. Researchers measure…

This study tested whether a 12-week home-based program of walking and resistance band exercises could improve physical fitness, fatigue, and quality of life for 36 breast cancer patients in Indonesia. Participants used pedometers and resistance bands at home, with weekly phone ch…

This study tests whether craniosacral therapy, a gentle hands-on technique, can improve quality of life in women who have finished breast cancer treatment. 102 survivors with reduced well-being are randomly assigned to one-on-one therapy, group self-help training, or a waiting li…

This study tested a special dressing coated with a substance that binds bacteria (DACC-coated hydrogel) to treat skin burns caused by radiation therapy in 18 women with breast cancer. The goal was to see if it could reduce pain and help heal the skin. The study is already complet…

This study compared two types of nerve blocks — the erector spinae plane block and the retrolaminar block — for controlling pain after major breast cancer surgery. Ninety women between 18 and 60 years old took part. Researchers measured pain scores and how much opioid painkiller …

This study looked at whether giving the painkiller tapentadol before breast cancer surgery could lower the amount of morphine needed during and right after the operation. Seventy patients took either tapentadol or a placebo one hour before surgery. Researchers measured morphine u…

This study looked at whether taking hormone therapy for breast cancer in the morning or evening reduces side effects and helps patients stay on treatment. 245 women with early-stage breast cancer were randomly assigned to take their medication either within an hour of waking or w…

This study tested whether giving midazolam, a sedative, before breast conservation surgery reduces anxiety and improves satisfaction. 124 women were randomly assigned to receive either midazolam or a placebo. Their anxiety was measured before and after the drug, and satisfaction …

This study looks at whether physical therapy can help breast cancer patients who develop axillary web syndrome (a condition causing tight, painful cords under the arm) after surgery. Researchers will compare patients who receive physical therapy to those who don't, measuring impr…

This study looked at whether a structured exercise program (adapted physical activity) could improve thinking and quality of life in women treated for locally advanced breast cancer. 37 women who had chemotherapy and reported memory or concentration problems took part. Half start…

This study tested whether physical therapy and education before breast cancer treatment can help prevent or reduce side effects like joint pain, muscle weakness, and fatigue. 75 newly diagnosed patients were randomly assigned to either the MOve-ABC program (physical therapy, home…

This study looked at whether giving vitamin C around the time of breast cancer surgery can lower pain right after surgery and months later. 204 women having a mastectomy or lumpectomy took part. Half received vitamin C, half a placebo, and pain levels were tracked for up to 6 mon…

This study tested whether taking Coenzyme Q10, a natural antioxidant, can help prevent or reduce side effects from chemotherapy in breast cancer patients. Forty women newly diagnosed with breast cancer and about to start chemotherapy took either Coenzyme Q10 or a placebo. Researc…

This study tested an online nurse-led program to help young women who had breast cancer improve their sexual health, body image, and menopausal symptoms. 43 women who finished treatment within the last five years took part in eight weekly sessions. The program aimed to see if it …

This study tested whether a 6-week supervised exercise program could improve quality of life and reduce fatigue in 78 breast and colon cancer patients. Participants were randomly assigned to either the exercise program or usual care, and were followed for one year. The main goal …

This study tested whether self-acupressure—using fingers to press on specific points on the body—can reduce joint pain and stiffness caused by aromatase inhibitors, a common hormone therapy for breast cancer. Fifty postmenopausal women with breast cancer learned to do acupressure…

This study looked at whether exercise or nutrition education can reduce nerve pain caused by chemotherapy in women with breast cancer. 80 women took part in a phase 2 trial comparing the two approaches. The goal was to see if these lifestyle changes could help manage symptoms and…

This study looked at whether the MyChart app can help track hot flash treatments in breast cancer patients. About 56 adults with breast cancer and hot flashes took part. The goal was to see if using the app is a good way to collect information on which treatments work best for ma…

This study looked at whether adding a mindfulness-based stress reduction program to an 8-week exercise plan could improve fitness and quality of life in women with breast cancer. 100 women who had finished chemotherapy and were undergoing radiotherapy or hormone therapy took part…

This study tested a digital information tool called Digi-Do for breast cancer patients undergoing radiotherapy. The tool was designed to help patients feel more involved and prepared before, during, and after treatment. Researchers measured changes in distress and self-efficacy i…

This study tested a mobile app called WeCanManage designed to help cancer survivors with disabilities manage long-term effects of their illness and treatment. Twenty adults who had breast cancer, head and neck cancer, or sarcoma used the app and reported on how helpful and easy i…

This study looked at whether ear acupuncture can ease hot flashes in women with breast cancer who are taking hormone-blocking pills. 107 women took part, comparing two types of ear acupuncture. The goal was to see if this simple treatment could improve their daily comfort and qua…

This pilot study tested whether a 4-week online sleep therapy program (CBT for insomnia) could help breast cancer survivors take their daily hormone-blocking pills more regularly. 35 women with insomnia who sometimes missed their medication took part. The goal was to see if impro…

This study tested whether a traditional Daoist exercise called Shangshou Dao-yin could improve sleep, body constitution, and quality of life in breast cancer patients undergoing chemotherapy. 150 women who had surgery for breast cancer and were starting chemotherapy were assigned…

This study tested a mobile health program to help breast cancer patients in medically underserved areas manage pain and disability. 180 women with breast cancer and persistent pain took part in four video-conferencing sessions over eight weeks, learning coping skills from a remot…

This study tested whether a 12-week health education program (including group meetings and social media tips) could improve lifestyle habits, physical activity, and emotional well-being in women being treated for breast cancer. Twenty-eight women took part. The goal was to see if…

This study tested whether telemedicine and connected watches can help monitor symptoms and improve quality of life for women with advanced breast cancer who live far from their cancer center. Fifteen patients reported symptoms weekly on a tablet, while a smartwatch tracked their …

This study tested whether a hand massage before inserting an IV can help breast cancer patients undergoing chemotherapy. Sixty patients were split into two groups: one received a hand massage, the other did not. Researchers measured how quickly the IV was placed, patient anxiety,…

This pilot study tested whether a mindfulness program could help prevent chemo-brain in women about to start chemotherapy for breast cancer. Fifteen women participated in mindfulness sessions and underwent brain scans and blood tests. The main goal was to see if women would stick…

This study looked at whether giving a light electrical pulse to a specific spot on the wrist (called P6) during breast cancer surgery could help prevent nausea and vomiting after the operation. 188 women at high risk for post-operative nausea took part. The goal was to see if add…

This study tested whether a gel made from birch bark extract (Oleogel-S10) can help heal skin burns caused by radiation therapy in breast cancer patients. 18 women with moderate to severe radiation dermatitis used the gel along with a standard steroid cream. The goal was to see i…

This study compared two different schedules of proton therapy after mastectomy in 88 women with breast cancer. One group received 15 treatments, the other 25, to see if the shorter course was as safe and effective. The goal was to reduce side effects and treatment burden without …

This study looked at whether myofascial release exercises (a type of gentle stretching) can help breast cancer patients who have had radiation therapy. 30 women who had breast cancer surgery and were about to start radiation took part. The goal was to see if these exercises could…

This study tested two methods to control pain after a mastectomy: a nerve block in the back (erector spinae plane block) and numbing medicine injected into the wound. 37 women took part. The goal was to see which approach reduces pain and the need for morphine in the first day af…

This study tested a 6-week online pain management program for breast cancer survivors who still have bothersome pain after treatment. The program included education, exercises, and psychological strategies to cope with pain. Researchers wanted to see if it helps reduce pain's imp…

This study looked at whether starting a personalized exercise program before breast cancer surgery helps women recover better. Thirty female survivors followed the program for 12 months. The goal was to improve shoulder motion, reduce pain, and enhance daily function and quality …

This study looked at whether a tailored exercise program, done either before or during standard breast cancer treatment, could reduce side effects like heart damage and muscle loss. One hundred women with early-stage breast cancer participated. The goal was to see if exercising b…

This study tested two ways to prevent chronic pain after mastectomy: a nerve block (erector spinae plane block) using ropivacaine, and intravenous lidocaine. Eighty women undergoing breast surgery were split into two groups and followed for 6 months. The goal was to see which met…

This study tested whether a program of therapeutic exercise and relaxation techniques (called ATENTO) could prevent nerve damage (neurotoxicity) in women newly diagnosed with breast cancer. 42 women were split into two groups: one started the program before cancer treatment, the …

This study tested four different nerve blocks (erector spinae, retrolaminar, serratus anterior, and pectoral nerve block) to see which one provides the longest pain relief after breast cancer surgery. 188 women aged 18 to 65 took part. The main goal was to measure how long it too…

This study looked at 96 women having breast-conserving surgery for cancer. It compared two types of anesthesia: a nerve block (PECS) and general anesthesia. The goal was to see which one helps patients recover better, with less pain and fewer side effects right after surgery.

This pilot study tested whether a non-invasive brain stimulation technique called tDCS could improve balance and thinking in older women who had chemotherapy for breast cancer. 48 women aged 50-85 took part. The results will show if this approach can help with common side effects…

This study tested whether a mobile app called IntelliCare can reduce depression and anxiety in breast cancer survivors. 313 women who had been diagnosed within the past 5 years and had elevated symptoms used the app or received standard educational materials. The study also looke…

This study tested a remote coaching program called PRISM to help women with breast cancer build resilience and improve their quality of life. 43 women with early-stage or metastatic breast cancer took part. The program focused on stress management, goal-setting, and positive thin…

This study tested whether a brief mindfulness program could improve emotional well-being and quality of life in women with early-stage breast cancer. 42 women watched educational videos, listened to guided meditations, and wrote reflections before and after surgery. Researchers m…

This study tested a telephone-based therapy called Managing Anxiety from Cancer (MAC) for older adults (65+) with cancer and their caregivers. The therapy includes seven sessions covering relaxation, communication, and problem-solving skills. The goal was to see if it reduces anx…

This study tested a physical activity program for breast and endometrial cancer survivors who were not getting enough exercise. Participants started with a Fitbit activity tracker linked to their electronic health record, and those who did not improve were offered extra support l…

This pilot study tested a collagen-based food supplement (Tenflex®) in 30 women with breast cancer who had joint pain from hormone therapy (aromatase inhibitors). The goal was to see if pain levels improved over 12 weeks. The supplement is already sold as a food product, so this …

This study tested whether an ultrasound-guided PECS nerve block could reduce opioid use and improve pain control in 70 women undergoing breast cancer surgery. Participants received either the nerve block or standard care. The goal was to see if the block leads to less pain, less …

This study tested whether watching 360° virtual reality movies can reduce fear and anxiety in cancer patients about to start radiation therapy. 292 adults with breast, lung, prostate, head and neck cancer, or brain tumors participated. Patients watched a VR movie and then filled …

This study tested whether adding dexmedetomidine or dexamethasone to a standard numbing medicine (bupivacaine) in a nerve block could improve pain control after breast removal surgery. 70 adult women undergoing modified radical mastectomy received one of three mixtures. The goal …

This study tested whether a mobile app could help people with early breast cancer follow their treatment plan and improve their quality of life. 540 participants either used the app for reminders, tips, and communication with their care team, or received standard follow-up. The g…

This study adapted a 6-session behavioral therapy called FORT for Turkish breast and ovarian cancer survivors to help them manage fear of cancer recurrence. Researchers worked with 100 participants to translate and test the therapy, measuring changes in fear, anxiety, and quality…

This study looked at 42 breast cancer patients having a mastectomy to see which nerve block works better for pain relief. One group got a pectoral plane block, the other an erector spinae plane block. The main goal was to measure how much morphine they needed in the first 24 hour…

This phase 3 trial tested whether adding prochlorperazine or olanzapine to standard anti-nausea medication (netupitant/palonosetron and dexamethasone) better controls nausea and vomiting caused by chemotherapy in breast cancer patients. Over 1,300 women receiving common chemo dru…

This study tested whether a specific nerve block (Pecs block) using a non-opioid painkiller called Exparel can reduce pain, nausea, and the need for opioids after breast reconstruction with tissue expanders. Sixty adults undergoing this surgery were randomly assigned to receive e…

This study tested whether a surgical glue called Ifabond can reduce seroma—painful fluid collections—after breast cancer surgery. 104 women having partial mastectomy with or without lymph node removal were randomly assigned to receive standard surgery plus the glue or standard su…

This study looked at whether a single injection of numbing medicine between the ribs (rhomboid intercostal block) can lower the chance of chronic pain after mastectomy. 254 women having breast cancer surgery were split into two groups: one got the block, the other did not. Resear…

This study tested whether a low dose of the sedative dexmedetomidine could help women leave the hospital sooner after day-case breast cancer surgery. 82 women were randomly assigned to receive either the drug or a placebo during surgery. The main goal was to see how many could be…

This study tested two skin treatments—a hydrogel dressing and a water spray—for women with breast cancer who developed skin irritation from radiotherapy. The goal was to see which one better prevented treatment delays or the need to switch care. 278 women with mild to moderate sk…

This study looked at whether giving ketamine during anesthesia can reduce the need for morphine and lower pain after breast cancer surgery. About 230 adults having a mastectomy or lumpectomy took part. The goal was to see if ketamine helps avoid morphine's side effects.

This study tested whether a newer nerve block called ESP works as well as the standard PVB block for pain after breast cancer surgery. 292 women received one of the two blocks before surgery. The main goal was to see how many needed morphine in the first two hours after surgery. …

This pilot study tested whether self-acupressure (pressing specific points on the body) or Zhan Zhuang (a gentle standing meditation) can reduce pain, fatigue, and sleep problems in breast cancer survivors. Fifty women who had finished early-stage breast cancer treatment and stil…

This study tested whether using augmented virtual reality (AVR) during chemotherapy can help reduce pain, stress, and anxiety while boosting self-confidence. 150 adult cancer patients in the West Bank were split into two groups: one received standard care, and the other used AVR …

This study tested whether group dance classes can improve balance and motivation in breast cancer survivors who have nerve damage from chemotherapy. Fifty-two survivors participated in either dance-based exercise or standard exercise for several weeks. The goal was to see if danc…

This pilot trial tested a behavioral program called ActiveHeal EST in 30 adults recently diagnosed with breast or prostate cancer. The program includes group sessions and home activities to help survivors persist in daily tasks despite challenges. Researchers measured changes in …

This study tested whether auriculotherapy (a form of ear acupuncture) can reduce muscle and joint pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. 197 postmenopausal women with breast cancer who had pain for at least 3 months were randomly assigned…

This study compared two ways to manage pain after major breast cancer surgery: a nerve block called erector spinae plane block (ESPB) and an intravenous lidocaine drip. 80 adults having breast cancer surgery were randomly assigned to one of the two methods. The goal was to see wh…

This pilot study tested whether low-energy shock wave therapy can help people with axillary web syndrome, a common complication after breast cancer surgery that causes painful, tight cords under the arm. Twenty patients received four weekly sessions of shock waves to the affected…

This study tested two drugs, dexmedetomidine and lidocaine, given during surgery to control pain after a mastectomy. 40 women took part. The goal was to see which drug delays the need for extra pain medicine and keeps vital signs stable.

This study looks at whether breast cancer patients with mild, moderate, or severe liver problems face a higher risk of a serious side effect—grade 4 neutropenia (a dangerous drop in infection-fighting white blood cells)—when taking the drug palbociclib. Researchers analyzed medic…

This study investigates whether women who have completed breast cancer treatment have a higher chance of developing colorectal polyps or colon cancer. Researchers will perform screening colonoscopies in 216 asymptomatic breast cancer survivors and check for abnormal growths. The …

This study examined how Mexican-American families discuss their risk for diabetes, heart disease, breast cancer, and colon cancer. Researchers interviewed 498 adults from Mexican-American households in Houston to understand how culture and family history influence health communic…

This study looked at whether having a special consultation with a radiotherapy technician (called a manipulator) helps cancer patients feel more informed about their treatment. Researchers enrolled 308 adults with various cancers who were getting radiation therapy. They compared …

This study looked at whether using a physical activity screener, along with exercise coaching and self-monitoring, could help breast and colon cancer survivors become more active and spend less time sitting. Twenty survivors who had finished their main cancer treatment at least t…

This study tested whether a weekly electronic survey could help identify cancer treatment delays and racial differences. About 100 adults with newly diagnosed breast or colorectal cancer who hadn't started treatment yet filled out a short survey each week for 8 weeks. The goal wa…

This study tested new screening methods like MRI, duct lavage, and PET scans in 200 women with BRCA gene mutations who are at high risk for breast cancer. The goal was to see if these tools can find cancer earlier than standard mammograms. Participants were followed for three yea…

This completed study looked at whether a simple blood test (liquid biopsy) can help track breast, ovarian, and endometrial cancers. Researchers analyzed circulating tumor cells in 150 women to see if these cells could predict the risk of cancer spreading or how well treatment wor…

This study looked at two ways to help breast and ovarian cancer survivors get genetic counseling: a mailed brochure or a phone call with a health coach. About 668 women took part. The goal was to see which method led more people to actually get genetic counseling or testing. The …

This study tested whether a short video featuring cancer survivors and local leaders could encourage more people in rural Tamil Nadu to get screened for oral, breast, and cervical cancer. Over 1,200 adults aged 30-59 who had not been screened recently were randomly assigned to se…

This completed study analyzed tissue samples from 108 breast cancer patients to identify proteins linked to early cancer invasion. The goal was to find markers that could help assess the risk of tumor spread in patients without lymph node involvement. Researchers focused on listi…

This study tested three types of messages to encourage genetic testing in 1,283 people at risk for hereditary breast and ovarian cancer. Participants received an electronic health record message, then a text message, then a doctor's reminder if needed. The goal was to see which a…

This study looked at how common BRCA1 and BRCA2 gene mutations are in Hispanic/Latino women with breast cancer. Researchers collected saliva samples and medical history from 266 participants to better understand these mutations in this group. No treatment was given; the goal was …

This study looks at medical records from 750 people with a common type of early breast cancer (HR+/HER2-). It aims to understand how doctors treat these patients in real life, especially after newer targeted drugs called CDK4/6 inhibitors became available. By analyzing treatment …

This study looks at how a common breast cancer medicine called an aromatase inhibitor changes the bacteria in your gut. Researchers will collect stool and blood samples from 25 women before and after starting the medicine to see how gut bacteria shifts and how that affects estrog…

This study explored whether a simple blood test measuring the neutrophil-to-lymphocyte ratio (NLR) can help predict how well women with advanced breast cancer respond to a common treatment (CDK4/6 inhibitors plus hormone therapy). Researchers followed 165 patients starting this t…

This completed study from the University of Central Florida involved 24 women diagnosed with breast cancer. Through online questionnaires and focus groups on Zoom, researchers explored how the disease and its treatment affect sexual health, intimacy, and relationships. The goal i…

This study measured levels of a protein called IP3R3 in breast cancer tissue from 42 women. The goal was to see if this protein is involved in how cancer cells migrate and invade nearby tissues. Researchers hope this could lead to better understanding of what makes breast cancer …

This study aimed to create a personalized 3D computer model of the breast to help surgeons better understand where tumors are located during surgery. Researchers measured skin elasticity and thickness in 200 women, and performed special MRI scans on 10 women in different position…

This study collected information from 93 men who have had breast cancer. Participants filled out a questionnaire about their life, work, family, and health history. The goal is to find patterns that might help explain why some men develop breast cancer. No treatments or drugs wer…

This study looked back at 1,030 breast cancer patients to see how radiotherapy affected their chances of staying cancer-free and living longer. The goal was to understand radiotherapy's real benefits and help doctors design better treatment plans in the future.

This study looked at how the body absorbs, breaks down, and gets rid of a new breast cancer medicine called HRS-8080. Six healthy postmenopausal women took a single dose of the drug with a radioactive tag so researchers could track it. The goal was to understand the drug's path t…

This study tested whether a breast cancer education program could improve knowledge and awareness among 40 incarcerated women in Turkey. Participants completed surveys before and after group training sessions, with a reminder session one month later. The goal was to see if educat…

This study looked at memory complaints in 426 people, including those with brain tumors, breast cancer, and healthy volunteers. Participants filled out questionnaires about their memory, mood, and fatigue. The goal was to understand how cancer and its treatments might affect ever…

This study examined the vaginal microbiome—the community of bacteria and other microbes—in 35 women with breast cancer who were receiving hormone therapy. The goal was to see if certain bacteria are linked to vaginal dryness and sexual health. Researchers collected vaginal swabs …

This completed study looked at medical records of over 1,100 people in Australia who took CDK4/6 inhibitors (like palbociclib) for advanced or metastatic breast cancer. Researchers wanted to understand patient characteristics, dosing, and how long people stayed on treatment in re…

This completed study looked at 121 women in Brazil with a certain type of advanced breast cancer (HR+/HER2-). Researchers tracked how doctors prescribed palbociclib combined with other drugs in everyday practice, not in a strict trial setting. The goal was to describe patient bac…

This study tested whether time-restricted feeding (eating only during an 8-hour window each day) could change certain blood markers linked to breast cancer risk. Twenty-nine postmenopausal women with prediabetes were randomly assigned to either the 8-hour eating schedule or a nor…

This study tested whether an artificial intelligence (AI) model can accurately measure heart rhythm changes (QTc) from ECGs in 70 breast cancer patients starting the drug ribociclib. The goal was to see if simpler ECG devices could work as well as standard 12-lead machines when a…

This study looked at medical records from over 1,300 breast cancer patients in Japan who took the drug palbociclib. The goal was to find out which patients are more likely to develop a severe drop in white blood cells (grade 4 neutropenia), a known side effect. Researchers compar…

This study tested whether a two-hour, peer-led workshop with religious messages could encourage Muslim women in North East England and Scotland to get screened for breast, bowel, and cervical cancer. 169 women aged 25-74 who were not up-to-date with all eligible screenings took p…

This study tested a simple, self-administered scoring system to identify moderate to severe nerve damage caused by chemotherapy in breast cancer survivors. 26 women who had taxane-based chemotherapy and radiation took part. The goal was to find the best score that separates those…

This early-phase study tested the drug HRS-8080 in 24 healthy adults to see how well it is absorbed and whether food changes its levels in the body. Participants took single doses under different conditions, including fasting and with low- or high-fat meals. The results will help…

This study tested a custom-made device called the Breast Cancer Locator (BCL) in 35 women with non-palpable breast cancer. The device helps surgeons see exactly where the tumor is during breast-conserving surgery, with the goal of removing all cancer in one go and reducing the ne…

This study looked at whether breast cancer survivors have reduced arm exercise capacity and oxygen use compared to healthy people. Researchers tested 60 women (30 survivors and 30 healthy) using an arm bike and muscle oxygen monitor. The goal was to better understand long-term ef…

This completed study looked at ways to increase diversity in cancer clinical trials, focusing on breast, liver, and prostate cancers. Researchers worked with communities, doctors, and scientists in New York City to find better ways to include people of color and underserved group…

This study looked at 220 women with HER2-low advanced breast cancer whose disease progressed after antibody-drug conjugate (ADC) therapy. Researchers compared different follow-up treatments, such as other ADCs, chemotherapy, hormone therapy, or immunotherapy, to see which worked …

This study tested a digital health platform to help people with a hereditary risk of breast and ovarian cancer share their genetic test results with family members. Researchers worked with 128 participants in Switzerland and Korea to see if the tool reduced distress and improved …

This study examined blood samples from 49 women with metastatic breast cancer to find genetic markers that predict side effects from trastuzumab (Herceptin). The goal was to understand why some patients experience heart or allergic reactions. It did not test a new treatment, but …

This study offered a rapid hepatitis C test to 1,500 women aged 50-74 who were already coming in for breast cancer screening in Montpellier, France. The goal was to see how many women would agree to the extra test and how many had undiagnosed hepatitis C. Women who tested positiv…

This study tested whether an extract of American ginseng root (LEAG) could change certain markers in breast cancer tumors. Sixteen women took ginseng tablets for 5–14 days before their surgery. Researchers measured changes in inflammation and growth-related proteins in the tumor …

This completed study followed 830 women who had early or locally advanced breast cancer and finished their main treatment (except hormone therapy). The goal was to understand their health-related quality of life using several questionnaires. No new treatment was tested; instead, …

This study tested a website and mobile app called BC-Navigate, designed to help Black women and other women of color start chemotherapy on time after breast cancer surgery. The goal was to see if the app was easy to use and could reduce racial inequities in cancer care. Researche…

This study surveyed 385 women aged 35 or younger with early-stage breast cancer to learn their attitudes about the risk of infertility from adjuvant therapy. The goal was to understand how concerns about having children might influence their treatment choices. The results could h…

This study tested a new cone-beam CT scanner that takes clearer pictures during radiation therapy for lung, liver, and breast cancers. 31 people participated to see if the new scanner reduces image blurring and improves accuracy. The goal is to help doctors target tumors more pre…

This study looked at whether a special, graph-based genetic counseling method helps newly diagnosed breast cancer patients better understand their risk of cancer in the other breast and make more informed surgery choices. About 400 patients participated, comparing this new approa…

This completed study looked at whether a deficiency in the DPD enzyme can predict severe side effects from the chemotherapy drug capecitabine in women with metastatic breast cancer. Researchers analyzed blood samples from 303 participants to see if genetic differences could help …

This completed study surveyed over 500 breast cancer patients from low-income and minority groups in Northern California to find out what stops them from getting genomic testing. Researchers used an online survey and phone interviews to gather information. The goal was to identif…

This study tested a community-based program to help homeless women complete mammograms for breast cancer screening. Researchers surveyed 203 women living in shelters and provided a brief educational session on breast health. The goal was to identify and overcome barriers to scree…

This study tested whether a flexible, personalized exercise program is practical for cancer patients receiving chemotherapy. Twenty-one adults with breast, ovarian, or colorectal cancer took part. The main goal was to see if patients would join, attend, and stick with the exercis…

This study looked at 220 women having breast surgery to see if a blue dye called methylene blue, used to find lymph nodes, changes blood pressure or heart rate during anesthesia. The researchers compared women who got the dye with those who did not. The goal was to learn if the d…

This study looked at 120 women having mastectomy for breast cancer to see if the gender of their anesthesiologist affected their pain and need for painkillers after surgery. Researchers compared pain scores and medication use between patients treated by male versus female anesthe…

This study tested whether a simulation-based breast health class could improve breast cancer awareness and self-exam habits among Afghan refugee women. 46 women aged 20-65 who spoke Turkish or Dari took part. The goal was to see if this teaching method helps them recognize sympto…

This completed study looked at how women ages 39-49 make decisions about breast cancer screening. Participants read a decision aid explaining the pros and cons of mammograms and then answered surveys about their reactions, knowledge, and screening plans. The goal was to understan…

This completed pilot study looked at how the drug tamoxifen affects breast cancer tumors at a molecular level. Researchers studied 59 patients with a specific type of breast cancer to see how tamoxifen changes the interaction between two key proteins. The goal was to gather infor…

This completed study analyzed medical records of 1,170 advanced breast cancer patients in Japan to see how they used the drug palbociclib (Ibrance). Researchers looked at blood test frequency and how long patients stayed on treatment. The goal was to describe real-world treatment…

This completed study looked at 470 women with breast cancer in Paris to understand how their background affects their experience. It compared women born in France with those born in sub-Saharan Africa, focusing on diagnosis timing, treatment access, and social impacts. The goal i…

This completed study analyzed health records from over 2 million people with type 2 diabetes to see if those taking dapagliflozin had a different risk of breast or bladder cancer compared to those on other diabetes medications. Researchers tracked cancer diagnoses for up to 12 ye…

This study tested whether focused questionnaires can detect lymphedema—a common complication after armpit lymph node removal—earlier than physical measurements like arm circumference. Researchers followed 101 breast cancer patients who had or were scheduled for axillary dissectio…

This study tested a program called REASSURE to help low-risk breast cancer survivors feel more prepared for their follow-up care. About 104 survivors took part for up to 18 months. The goal was to see if the program improved their confidence and reduced unnecessary care.

This study looked at whether it's possible to measure certain substances called oxysterols in the blood of breast cancer patients. 29 women taking hormonal therapy (tamoxifen or anti-aromatase drugs) had their blood tested before and 28 days after starting treatment. The goal was…

This study looked at whether tiny molecules called microRNAs in the blood can help predict if hormone therapy will work for women with advanced breast cancer. Researchers tested blood samples from 39 women before and after one month of treatment with tamoxifen or an aromatase inh…

This completed study involved 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers compared different surgery and radiation techniques to see which ones led to less breast hardening (fibrosis) and better cosmetic results. The goal was to find w…

This completed study looked at 480 patients with HR+, HER2- metastatic breast cancer who were treated with CDK4/6 inhibitors as their first therapy. Researchers examined patient profiles, treatment patterns, and outcomes in everyday clinical practice. The goal was to understand h…

This study looked at whether a tumor gene test called the 21 gene Recurrence Score (OncotypeDx) changes doctors' recommendations for chemotherapy in women with early-stage, hormone receptor-positive breast cancer that has spread to lymph nodes. Researchers tracked how often chemo…

This study looked at whether using a special ultrasound ruler during breast-conserving surgery helps surgeons remove all cancer the first time. Researchers reviewed records from 273 patients who had this ultrasound-guided surgery. The goal was to see if it lowered the rate of inc…

This study looked back at medical records of 693 Japanese patients with a certain type of advanced breast cancer (HR+/HER2-) who received palbociclib plus endocrine therapy as their first or second treatment. Researchers measured how long patients lived without the cancer getting…

This study combined data from over 5,300 people with early-stage breast cancer who received a specific type of chemotherapy. Researchers wanted to see how long patients lived without the cancer coming back and what side effects they had. The goal is to learn from past treatments …

This study tested whether a personalized psychological program given before and after breast cancer surgery could lower stress and change certain markers in the tumor linked to cancer spread. Forty women with early-stage breast cancer took part. Half received the psychological su…

This study tested whether a personalized follow-up plan (with on-demand nurse access and annual phone calls) works as well as standard clinic visits every 3-6 months for early-stage breast cancer patients. 261 women who finished initial treatment took part. The goal was to see if…

This study looked at 120 adults with breast, pancreatic, or biliary cancer to see if a new 3D measurement method (TDTP-RECIST) is better than the standard way (RECIST 1.1) for tracking tumor shrinkage before surgery. Researchers compared imaging results with actual tumor tissue r…

This completed early study tested a special clip-on electrode with fiber optics that detects light signals during breast cancer surgery. The goal was to see if the device is safe and can help surgeons identify different tissue types in real time. Twenty-four women with invasive b…

This study looked at medical records from over 218,000 adults in England with a common type of breast cancer (HR+/HER2-). Researchers tracked which treatments people received, how the disease progressed over time, and how healthcare resources were used. The goal was to understand…

This study looked at skin samples from 20 breast cancer patients receiving radiation therapy to understand why some develop radiation dermatitis—itchy, red, swollen skin. Researchers took small skin biopsies from areas showing signs of irritation. The goal was to identify molecul…

This study tested a new device called the EnVisio SmartClip that helps doctors mark and find breast tumors during surgery. 50 people with breast cancer took part. The goal was to see if the SmartClip makes it easier for surgeons to locate and remove the right tissue.

This study looked at 35 women with early-stage breast cancer who do not currently qualify for genetic testing under standard guidelines. It compared the use of an artificial intelligence program for pre-test genetic counseling versus traditional in-person counseling. The goal was…

This study observed over 2,400 women in Russia with advanced HR+/HER2- breast cancer to see how well different treatments work in everyday medical practice. Researchers tracked how long patients stayed on their therapy before it stopped working or caused side effects. The goal wa…

This study looked at how women aged 65 and older with early-stage breast cancer choose among three options after surgery: standard weeks-long whole-breast radiotherapy, a single dose of radiation during surgery, or no radiation at all. Researchers surveyed 104 patients to underst…

This study looked at how women aged 39 to 49 react to scientific information about mammography's benefits and harms. Researchers measured feelings like disbelief, distrust, and thinking the information doesn't apply to them. The goal was to understand how these reactions influenc…

Breast cancer in men is rare, making up only 1% of cases, and most research has focused on women. This study aims to develop a questionnaire specifically for men with breast cancer to measure their quality of life. Researchers interviewed 65 patients and healthcare professionals …

This study looked at how closely 200 adults with advanced breast or prostate cancer follow their prescribed oral cancer treatments. Participants filled out questionnaires about their medication use and gave blood samples to check certain health markers. The goal was to understand…

This study looked at nearly 1,000 cancer survivors to find out which follow-up care model works best for their quality of life and satisfaction. Participants were breast, prostate, or colorectal cancer survivors who had finished active treatment. Researchers compared different ca…

This completed study looked at whether sampling just a few lymph nodes under the arm can tell if breast cancer has spread, instead of removing many nodes. Twenty patients with advanced breast cancer at diagnosis took part. The goal was to see if this targeted approach could reduc…

This study examined how well CDK4/6 inhibitors (a type of targeted therapy) work for people with advanced breast cancer in Egypt. Researchers looked at 206 patients to measure how long the drugs kept cancer from growing, side effects, and overall costs. The goal was to see if the…

This study measured how much physical activity 507 breast cancer patients in Spain get and what types of exercise they prefer. Researchers used questionnaires to understand current activity levels and exercise likes and dislikes. The goal is to use this information to design bett…

This study used functional MRI (fMRI) to see how the brain's sensory map changes after breast reconstruction in women treated for breast cancer. Researchers compared brain activity when touching the reconstructed breast versus the natural breast. The goal was to objectively measu…

This study analyzed blood samples from breast cancer patients to find genetic factors that might predict how well they respond to chemotherapy. Researchers looked at patients who had already received standard chemo drugs. The goal was to identify biomarkers that could guide futur…

This study looked at spinal fluid from 7 women with breast cancer that may have spread to the lining of the brain. Researchers analyzed proteins in the fluid to see if they can find a pattern that helps diagnose this condition. The goal was to learn more, not to test a treatment.

This completed study looked at how emotional skills affect the way young women (45 or younger) with non-metastatic breast cancer and their partners adjust to the disease. 391 couples filled out questionnaires at several points during treatment, from before chemotherapy to after r…

This completed Phase 3 study looked at how four different hormone therapies (anastrozole, exemestane, letrozole, and tamoxifen) affect memory in postmenopausal women with breast cancer. The 44 participants took one of these drugs for 6 to 12 months, and researchers tested their v…

This study looked at 28 women with breast cancer that spread to their bones. Researchers compared two types of scans—PET-CT and whole-body MRI—to see if they agree on whether the bone tumors are stable, improving, or getting worse. The goal is to find a reliable way to monitor tr…

This study tested a new questionnaire designed to measure quality of life in young women (under 45) with non-metastatic breast cancer and their partners. Over 1,000 couples completed the survey at home. The goal was to see if the questionnaire accurately captures the emotional an…

This completed Phase 2 trial looked at whether the sentinel lymph node technique—a less invasive way to check if cancer has spread—works for women with multifocal breast cancer (more than one tumor in the same breast). 216 women with early-stage, node-negative multifocal breast c…

Researchers developed and tested a short questionnaire called the Cancer Pathology Acceptance Questionnaire for Breast Cancer (CPAQ-8-BC) in 101 women with breast cancer. The goal was to see if it reliably measures how well a patient accepts her illness and stays engaged in life …

This study looked at spinal fluid from 51 breast cancer patients whose cancer may have spread to the lining of the brain and spinal cord (leptomeningeal metastases). Researchers compared a new blood test technique (CellSearch) with standard spinal fluid analysis to see which bett…

This completed study looked at blood and tumor samples from 66 women with breast cancer who were about to receive chemotherapy before surgery. Researchers searched for unique protein patterns that might show whether the tumor would shrink with treatment. The goal was to find a wa…

This study looked back at medical records of over 1,600 adults in Russia with HER2-low breast cancer that had spread or could not be removed by surgery. Researchers wanted to understand how common this type is, what patient characteristics are, and how doctors actually diagnose a…

This study looked at how breast cancer affects the quality of life of young women (under 45) and their life partners. Researchers interviewed 171 couples at different times during medical follow-up to understand emotional, social, and relationship challenges. The goal was to crea…

This study tested whether a mobile app-based education program could improve women's understanding of HPV and their attitudes toward breast cancer screening. Seventy women aged 30-65 used the app and completed surveys before and after the program. The goal was to see if the app c…

This study looked at whether a special PET scan (FDG-PET) can detect early whether breast cancer is responding to chemotherapy. 63 women with breast cancer had a PET scan before and after their first chemo cycle. The goal was to see if the scan could tell responders from non-resp…

This study looked at how calcium and vitamin markers change in 146 breast cancer patients receiving standard adjuvant chemotherapy. Researchers measured these markers before, during, and after treatment to understand metabolic effects. The goal was to see how often patients devel…

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to one of these two methods or to standard care. The goal was to se…

This completed study looked at over 4,400 women to compare long-term quality of life between those whose breast cancer was found through screening and those whose cancer was found through symptoms. Researchers measured quality of life at different times after diagnosis and also c…

This study tested whether breathing in humidified wood or fragrant oils could mimic the immune-boosting effects of a forest walk. 28 adults who finished chemotherapy or radiation for early-stage breast or prostate cancer took part. The goal was to see if this approach is practica…

This study looked at whether automated planning tools can be used with MRI scans to guide radiation therapy for breast cancer. The goal was to make treatment faster and more precise while avoiding extra radiation from X-rays. 63 female breast cancer patients took part to help ref…

This study checked if the cancer drug olaparib causes low folate (folic acid) levels in the blood. Ten women with advanced ovarian or breast cancer participated. Researchers measured folate levels and looked for related drops in hemoglobin. The goal was to understand side effects…

This study tested whether an online decision support tool helps young women (18-40) with breast cancer make more informed choices about preserving their fertility before starting cancer treatment. 186 participants either received standard oral information alone or used the online…

This study tested whether a special survivorship clinic, combined with an app for reporting symptoms, is practical for women who have finished curative treatment for early-stage breast, cervical, or endometrial cancer. Two hundred women visited the clinic at the start and end of …

This study tested a digital chatbot (called CATALYST) to help cancer survivors learn about genetic testing for inherited cancer risk. Fifty adults who had certain cancers (like breast, ovarian, or prostate) used the chatbot or received usual care. The goal was to see if the chatb…

This study reviewed medical records of women with advanced or metastatic HR+/HER2- breast cancer who received Palbociclib combined with hormone therapy in community clinics. The goal was to see how doctors actually prescribe these drugs, how long patients stay on treatment, and w…

This study tested whether an educational video series about sexual health is acceptable and useful for women undergoing breast cancer treatment. 32 women with early-stage breast cancer watched the videos over six months. Researchers measured how well the videos were received and …

This study looked at whether the ratio of index to ring finger length (2D:4D) is different in women with breast cancer compared to healthy women. Researchers measured the fingers of 132 women (79 with breast cancer, 53 without) and checked if the ratio related to tumor markers in…

This completed observational study in India enrolled 595 people with HR-positive, HER2-negative advanced or metastatic breast cancer who were already taking alpelisib plus fulvestrant. Researchers looked for PIK3CA gene mutations in tumors and tracked how well the cancer responde…

This study looked at whether chemotherapy before breast cancer surgery causes extra fluid buildup in the arm, an early sign of lymphedema. Researchers measured 111 women's arm fluid before and after chemo using a special device. The goal was to understand how often this happens a…

This study looked at data from 298 breast cancer patients to build a computer model that predicts whether chemotherapy before surgery will completely eliminate the cancer. The model uses routine clinical and lab information to estimate the chance of a complete response. It is not…

This study tested a website called 'Decide Together' that helps women aged 75 and older and their primary care doctors talk about the benefits and harms of mammography screening. The goal was to support shared decision-making, not to treat or prevent breast cancer. The study enro…

This study followed 67 women with breast cancer to see how chemotherapy given before surgery (neoadjuvant chemotherapy) affects their physical abilities. Researchers measured muscle strength, balance, and fatigue before and after treatment. The goal was to better understand the p…

This study looked at 171 women with early breast cancer to see if immune cells inside tumors are linked to how well chemotherapy works. Researchers also checked if certain markers in the blood could help predict cancer return. The goal was to better understand which patients migh…

This study looked back at the records of 471 women who had breast cancer surgery with immediate implant reconstruction. It compared a newer method using a tiny camera through small cuts (endoscopic) to the traditional method with a larger cut. The goal was to see which approach l…

This study tested a mobile health app designed to help Black women with breast cancer learn about clinical trials and decide whether to join. Eighty Black women with newly diagnosed breast cancer who had a smartphone or computer took part. The app provided education and a way to …

This study looked at 27 women with breast cancer who had a mastectomy and immediate breast reconstruction with an implant. The implant was placed either above the chest muscle (prepectoral) or below it (subpectoral). Researchers measured pain, arm function, quality of life, and c…

This study tested whether an AI-assisted software (iCurveE) helps doctors outline organs at risk on CT scans for radiation therapy more accurately and quickly. 500 adults with lung, breast, or esophageal cancer participated. Researchers compared manual outlining, AI-only, and AI-…

This study looked at whether adding a drug that targets specific genetic changes in breast tumors could slow cancer growth more than standard hormone therapy alone. It involved 19 people with ER-positive, HER2-negative breast cancer who received treatment before surgery. The goal…

This completed study tested a web-based decision aid called RealRisks in 70 high-risk women aged 35-74. The tool combines electronic health records and patient-reported data to calculate breast cancer risk and improve understanding of prevention options. Researchers measured whet…

This study looked at 3000 cancer patients to see which treatments work best for preventing dangerously low white blood cell counts after chemotherapy. It compared different approaches to see how well they prevent infections and improve quality of life. The goal is to give doctors…

This study looked at 172 breast cancer patients to see how proton radiation compares to standard photon radiation in terms of heart health. Researchers measured heart function and blood markers before, during, and up to one year after treatment. The goal was to understand which t…

This study looked at whether a blood test measuring how certain immune cells die after radiation can predict long-term side effects in breast and prostate cancer patients. Researchers enrolled 885 participants and tracked late complications. The goal is to personalize treatment t…

This completed study looked at how physical activity, fitness, and sitting time relate to insulin resistance (a diabetes risk factor) in 40 breast cancer survivors taking hormone therapy. Participants wore activity monitors and underwent tests for fitness, body composition, and i…

This study looked at 236 adults with breast, colorectal, or pancreatic cancer who sought a second opinion at the University of Colorado. Researchers reviewed medical records to see if patients stayed for treatment or went elsewhere. The goal was to understand what factors influen…

This study explored how African American women who survived breast cancer react to stress. Researchers measured stress hormones, heart rate, and blood pressure during a stressful task. They also looked at how stress might affect diet and exercise habits. The goal was to find new …

This study compared two types of skin grafts (Alloderm and Dermacell) used in immediate breast reconstruction after mastectomy. 62 women participated, and researchers tracked complications like infection, fluid buildup, and implant loss. The goal was to see if the cheaper option …

This completed study looked at why certain breast cancer drugs stop working over time. Researchers collected tumor samples from 269 patients to study genetic changes that might cause resistance. The goal was to better understand these mechanisms so that future treatments can be i…

This study looked at how to better educate women with breast cancer about sexual health during treatment. Researchers held focus groups with 93 patients to understand their needs and preferences. The goal was to create educational materials that could improve sexual well-being th…

This pilot study tested a combination of chemotherapy (Nab-Paclitaxel) and immunotherapy (Pembrolizumab) in 32 women with hormone receptor-positive, HER2-negative breast cancer before surgery. The main goal was to see how the treatment changed a biomarker called PD-L1 in tumor sa…

This study observed over 2,600 women in Germany with a common type of advanced breast cancer (HR+/HER2-). Researchers compared how long the cancer stayed under control when women started treatment with a drug combo (ribociclib plus hormone therapy) versus other hormone therapies …

This study tested a program called KanSurvive, which uses virtual education sessions and practice support to help rural primary care clinics improve follow-up care for cancer survivors. Researchers worked with 15 rural practices to see if they could better follow guidelines for m…

This study looked at how a common antifungal drug (itraconazole) changes the way the body handles a new experimental breast cancer drug (HRS-8080). Sixteen healthy adults took HRS-8080 alone and then with itraconazole to measure drug levels and safety. The goal was to gather info…

This study looked at 1,000 women who had breast reconstruction with implants right after mastectomy, followed by radiation therapy. Researchers compared two types of implants—polyurethane-covered and non-polyurethane-covered—to see which had fewer complications like capsular cont…

This study looked at 729 breast cancer patients who had surgery followed by radiation. Researchers checked their thyroid function before and after treatment to see how many developed an underactive thyroid (hypothyroidism). The goal was to find out which patients are at higher ri…

This study looked at whether sending reminders (nudges) to doctors or patients could increase the number of women with extremely dense breasts who get a breast MRI. Over 1,300 women aged 40-74 took part. The goal was to see if these nudges work better for Black or White women.

This study asked 714 breast cancer survivors about their experiences with the COVID-19 vaccine. Researchers wanted to understand if lymph node swelling—a common vaccine side effect—caused worry or raised the risk of lymphedema (arm swelling) in these patients. The study collected…

This study involved 562 premenopausal women in China with hormone receptor-positive breast cancer who received a GnRHa injection to suppress ovarian function after surgery. Researchers measured their quality of life and how well they followed the treatment plan using questionnair…

This study tested a new cone-beam CT scanner designed to take clearer images while patients are on the radiotherapy couch. 41 adults with head-and-neck, lung, breast, abdominal, or pelvic cancer each had one or two scans with the new device. The goal was to see if the images were…

This study looked at 100 women having a mastectomy to see if a device called the Analgesia Nociception Index (ANI) can detect when a nerve block isn't working. The device measures pain signals during general anesthesia. If it works, doctors could adjust pain treatment right away,…

This study surveyed 109 men with prostate cancer and women with breast cancer who were starting radiation therapy. Researchers asked about their use of complementary and alternative medicines (CAM), such as nutritional supplements, at three different times to see if their habits …

This study looked at how breast cancer treatments affect sexual health in 25 women. Participants filled out anonymous questionnaires about their sexual function, quality of life, and emotional well-being before and after chemotherapy. The goal was to understand how these factors …

This study looked at whether giving doctors a free online risk score (PREDICT 2.1) changes how often they order an expensive genetic test called Oncotype DX for early-stage breast cancer. Over 600 patients took part. The goal was to see if the algorithm could help doctors make be…

This early-stage study tested the safety of a single dose of Orialpha (BD-C), a drug made from the Uvaria grandiflora plant, in 15 healthy adults aged 18 to 60. Researchers monitored side effects and determined the highest safe dose. The study does not test whether the drug works…

This study looked at 200 women with early-stage HER2-positive breast cancer who were taking trastuzumab. The goal was to compare two standard schedules for monitoring heart function: every 3 months versus every 4 months. Researchers wanted to see if less frequent monitoring could…

This completed study looked at 70 breast cancer survivors to see how their physical activity levels relate to heart disease risk. Participants wore a special armband for a week to track activity, and researchers measured their heart risk using standard scores. The goal was to gat…

This study asked 167 people with cancer (and their caregivers) what they value most during pharmacy consultations for oral cancer drugs. Using a survey method, researchers identified key preferences to help hospitals design better support services. The goal was to improve patient…

This study looked at whether a low-dose vaginal estrogen tablet (Vagifem) is safe for women who have had breast cancer and are taking aromatase inhibitors. 31 postmenopausal women with a history of breast cancer used the tablet for vaginal dryness. Researchers measured their bloo…

This study tested whether radiologists can safely skip looking at detailed 3D breast scans when a quick 2D image or an AI score suggests the case is normal. Sixteen radiologists briefly viewed each case and rated how likely it was normal, then saw the AI's opinion. The goal is to…

This completed study in Japan reviewed medical records of 42 patients with HR+/HER2- advanced breast cancer who had been treated with palbociclib plus letrozole. The goal was to see how long patients lived after starting this treatment. It was a follow-up to an earlier phase 2 st…

This study tested whether osteopathic manipulative medicine (OMM) — gentle techniques like opening the chest and pumping the armpit — could help dye and radioactive tracer reach lymph nodes better than standard massage alone. 27 women having breast-conserving surgery for first-ti…

This study tested a program for adults aged 65-90 who had breast, colorectal, or prostate cancer. A community health worker assessed their health and provided coaching to address issues often missed after cancer treatment. The goal was to see if the program was feasible and could…

This study tested whether a high-resolution PET-CT scan of the removed tumor during breast-conserving surgery can help surgeons see if any cancer cells remain at the edges. About 206 women with early-stage breast cancer received a low-dose radioactive tracer before surgery. After…

This study looked at how DNA from tumors changes in the blood before, during, and after surgery for breast, prostate, or colon cancer. Thirty adults having curative surgery provided blood samples to measure these DNA levels. The goal was to understand the natural pattern of DNA c…

This study looked at the different types of cells inside breast tumors to better understand how they affect treatment response. Researchers used advanced molecular tools to analyze samples from 145 people with breast cancer. The goal was to gather knowledge that could lead to bet…

This completed study looked at 133 breast cancer patients to develop a way to predict who will get arm swelling (lymphedema) after lymph node removal surgery. Researchers examined patient characteristics, proteins, and genes to build a risk model. The goal is to help doctors iden…

This study looked at how different nerve blocks numb the skin for breast cancer surgery. Thirty-six patients received one of three types of nerve blocks before surgery. Researchers mapped the numb area and checked if it covered the surgical incision. The goal is to help doctors c…

This study tested whether an automated system can grow cancer cells from patient samples (blood, fluid, or tumor tissue) inside chicken eggs. Researchers aimed to see if at least half of the samples would successfully grow. The goal is to create a better, cheaper way to study can…

This completed study worked with healthcare workers, officials, and community members in Soweto, South Africa, to figure out the best ways to offer breast cancer screening using simple clinical breast exams in local clinics. Researchers observed clinic workflows and held group di…

This study looked at whether people with unstable living conditions are more likely to be diagnosed with advanced breast cancer. Researchers compared 684 patients with early-stage versus late-stage breast cancer. They found that social fragility may be linked to a later diagnosis…

This study looked at medical records of 779 older adults (65+) with a certain type of advanced breast cancer (HR+/HER2-). It compared survival in those who received a combination of the drug palbociclib plus hormone therapy versus hormone therapy alone. The goal was to see which …

This study looked at whether special heart MRI scans can spot early signs of heart damage in breast cancer patients after chemotherapy and radiation. Researchers followed 150 women for 12 months to see if heart swelling predicted a drop in heart function. The goal was to improve …

This study looked at whether giving cancer patients a decision aid before their doctor visit (on a smartphone) or during the visit (on paper) helps them feel more involved in treatment decisions. 274 adults with breast or colorectal cancer took part. The goal was to see which for…

This study involved 1,602 breast cancer patients and aimed to create a screening tool to predict long-term arm and shoulder problems like pain, swelling, and limited movement after treatment. Researchers used questionnaires and physical tests to identify women at high risk. The g…

This pilot study tested a patient navigator program for African-American adults with breast or prostate cancer. The goal was to see if having a navigator helps patients understand their treatment options and complete radiation therapy as planned. The study enrolled 30 people and …

This study looked at 123 women who had a mastectomy with immediate implant-based breast reconstruction. Half were sent home the same day, and half stayed overnight. Researchers compared complications, pain, and satisfaction within 30 days to see if same-day discharge is a safe op…

This completed study looked at how CDK4/6 inhibitors are used in everyday practice for advanced breast cancer in Portugal. Researchers analyzed data from 16 public hospitals to understand dosing patterns, treatment duration, and how often doses were adjusted. The study included n…

This study tested a noninvasive imaging method called Diffuse Optical Spectroscopy Imaging (DOSI) to see if it could predict how breast cancer responds to chemotherapy. Twenty-four women with breast cancer were scanned up to 9 times during their treatment. The goal was to see if …

This study reviewed medical records of 111 adults with early-stage HER2-positive breast cancer who received the drug neratinib after their initial treatment. The goal was to describe their age, gender, health conditions, and tumor details. This was an observational study, meaning…

This completed study looked at over 1,500 women with early-stage HER2-positive or triple-negative breast cancer who had no signs of cancer in their lymph nodes on ultrasound. All had breast-conserving surgery with lymph node removal. The goal was to see how often cancer actually …

This study looked at whether MRI scans can detect how well breast cancer responds to chemotherapy early in treatment. Sixteen women with invasive breast cancer received standard chemo before surgery, and their MRI results were checked by two radiologists. The goal was to see if M…

This study looked at whether a home body water analyzer can help detect lymphedema early in breast cancer survivors. Lymphedema is a common side effect of breast cancer treatment that causes arm swelling. 52 participants used the device at home for 12 months, and researchers comp…

This study looked at 422 breast cancer patients to understand what influences their beliefs about physical activity and their desire to be active. Researchers measured patients' knowledge of exercise benefits, their current activity levels, and fatigue. The goal was to learn how …

This study looked at small molecules called metabolites in breast cancer tumors to find patterns that could help understand the disease better. Researchers analyzed 52 tumor samples and some blood samples from patients who had surgery. The goal was to identify possible biomarkers…

This pilot study measured levels of a heart stress marker called NT-proBNP in 54 breast cancer patients during surgery. All patients had previously received anthracycline chemotherapy, which can weaken the heart. Researchers wanted to see if anesthesia might add extra stress. The…

This early-stage study gave a single dose of a radioactive-labeled version of the experimental breast cancer drug amcenestrant to 6 healthy postmenopausal women. The goal was to track how the drug is absorbed, broken down, and eliminated from the body. The results will help guide…

This study looked at whether sending text message reminders could increase the number of people who take part in colorectal and breast cancer screening programs. Over 44,000 eligible adults were included, and researchers compared SMS reminders to standard letters or no reminder. …

This study looked back at medical records of 517 women in Gulf countries with advanced breast cancer that was previously labeled HER2-negative. Researchers re-tested old tumor samples to find out how many actually have HER2-low breast cancer, a newer subtype. The goal is to bette…

This study reviewed medical records of 405 people in Egypt with advanced HER2-negative breast cancer to find out how many actually have a subtype called HER2-low. Researchers looked at past test results to estimate the prevalence. The goal is to better understand who might be eli…

This study looked at women aged 70 and older who finished treatment for early breast cancer within the last two months. Researchers used a survey called a geriatric assessment to find symptoms and problems the women were having. The results were shared with their medical team to …

This completed study looked at 312 patients with advanced breast cancer who received either trastuzumab deruxtecan or sacituzumab govitecan. Researchers collected real-world information on side effects and how long the cancer was kept under control. The goal was to see how these …

This study looked at 76 postmenopausal women with breast cancer to see if aromatase inhibitors affect balance and fall risk. Half the women had been taking the drug for at least a year, the other half never took it. Researchers measured balance using special tests and questionnai…

This completed study from the University of Central Florida involved 199 adults who had breast cancer imaging. Researchers created a social platform called MammoChat where patients could share their experiences anonymously. They also collected de-identified images to train AI mod…

This completed observational study looked at 110 breast cancer patients to see if arm swelling (lymphedema) is linked to a specific type of muscle pain called myofascial pain syndrome. Researchers examined trigger points in key muscles and measured pain thresholds. The goal was t…

This study looked at 300 breast cancer patients who had surgery, chemotherapy, and radiation. Many had complications like shoulder stiffness or swelling that needed rehabilitation. The goal was to create a computer model that could predict how long each person would need rehab. T…

This study tested a method to identify immune cells (T cells) that recognize unique mutations in tumors. Researchers took blood and lymph node samples from 25 patients with breast cancer or melanoma. The goal was to see if they could find and measure these cancer-specific immune …

This study looked at whether a personalized meal plan with more omega-3 fatty acids (found in fish) could reduce fatigue, pain, depression, sleep problems, and stress in women who finished treatment for early-stage breast cancer 1-2 years earlier. Researchers enrolled 98 women an…

This completed study looked at how two different anesthesia methods—general anesthesia and a nerve block called PECS block—affect certain immune cells in the blood of 50 women with breast cancer undergoing lumpectomy. The goal was to see if one method might be better for the immu…

This study measured blood flow in the skin of 62 people, including cancer patients who received 5-FU chemotherapy, those on other treatments, cancer survivors, and healthy controls. Researchers used a non-invasive laser sensor to see how small blood vessels responded to substance…

This study looked at how anthracycline-based chemotherapy affects blood vessel health and blood pressure control in 60 people with breast cancer or lymphoma. Researchers measured artery stiffness, blood flow, and skin blood vessel responses. The goal is to understand why cancer s…