BREAST CANCER

This early-phase study tested a personalized vaccine made from a patient's own immune cells, designed to target the HER-2 protein found on some aggressive breast cancers. The goal was to see if the vaccine is safe and can boost the immune system to prevent the cancer from returni…

This study tested a pill called hetrombopag in 60 people with advanced breast cancer who had low platelets from chemotherapy. The goal was to see if the drug could safely raise platelet levels and reduce the need for platelet transfusions or chemo delays. Results will help guide …

This study tested a drug called alpelisib combined with hormone therapy (fulvestrant or letrozole) in 383 people with advanced breast cancer that has a specific genetic mutation (PIK3CA). The goal was to see how many patients were alive without their cancer getting worse after 6 …

This early-phase trial tested a new drug, ARV-471, combined with everolimus in 32 people with advanced ER+/HER2- breast cancer that had stopped responding to other treatments. The main goals were to check safety and find the best dose. This is not a cure, but aims to better contr…

This study tested a shorter course of radiation for 108 women with breast cancer that had spread to their lymph nodes after surgery. The goal was to see if this faster treatment was safe and had manageable side effects like arm swelling or shoulder stiffness. Researchers tracked …

This study tested a cancer vaccine called ETBX-011 in 43 people with advanced cancers (colorectal, lung, breast, or prostate) that make a protein called CEA. The vaccine uses a modified virus to teach the immune system to attack cancer cells. The main goals were to check safety a…

This study observed 175 adults with HR+/HER2- advanced or metastatic breast cancer in the Middle East who received ribociclib combined with hormonal therapy. Researchers tracked side effects and how well the treatment controlled the cancer over 18 months. The goal was to understa…

This study tested whether montelukast, a drug used for asthma, can reduce heart damage caused by the chemotherapy drug doxorubicin in breast cancer patients. Fifty adults with breast cancer were randomly assigned to receive either montelukast or a placebo alongside their chemothe…

This early-phase trial looked at combining a special type of radiation (hypofractionated radiotherapy) with two immunotherapy drugs (MEDI4736 and tremelimumab) for people with advanced melanoma, lung, breast, or pancreatic cancer that had spread. The main goal was to find the saf…

This study tested an experimental drug called ART4215 in 93 people with advanced or metastatic solid tumors (cancers that have spread). The goal was to find a safe dose and see how well it works alone or combined with other cancer drugs (talazoparib or niraparib). Participants ha…

This study tested a new drug called CBX-12 in 69 adults with advanced solid tumors (like ovarian, lung, or breast cancer) that had stopped responding to standard treatments. The goal was to find a safe dose and see if the drug could shrink tumors. The study was completed, but res…

This study tested two hormone therapies, giredestrant and tamoxifen, in 92 premenopausal women with early-stage breast cancer. Participants took the drug for 15 days before surgery to see how well it slowed tumor growth. The goal was to compare the drugs' effects on cancer cell a…

This study tested a surgery called nipple-sparing mastectomy in 450 women with early-stage breast cancer. The goal was to see if removing the breast tissue while keeping the nipple and skin could keep cancer from coming back in that area. The approach aims to improve how the brea…

This study observed 178 Chinese patients with advanced HER2-positive breast cancer who received the drug T-DM1 after earlier treatments failed. Researchers tracked side effects and how long the drug kept the cancer from growing in real-world settings. The goal was to confirm that…

This study tested a personalized nutrition and physical activity counseling program for breast cancer survivors who were overweight. The program included both in-person and phone sessions to make it easier to participate. The goal was to help participants lose weight, improve bod…

This study tested whether adding the drug nintedanib to standard chemotherapy (docetaxel) helps people with HER2-negative breast cancer that has spread or come back. 51 adults participated. The main goal was to see if the combination slowed cancer growth for at least 6 months. Re…

This early-phase study tested a custom-made yeast vaccine designed to teach the immune system to recognize and attack leftover cancer cells. Five adults with different solid tumors (like colorectal, breast, or lung cancer) who had already completed curative treatment received the…

This study looked at how well the drug ribociclib works in Indian women with a certain type of advanced breast cancer (HR+, HER2-). Researchers collected data from medical records of 335 patients across 18 hospitals in India. The goal was to see how long the drug kept the cancer …

This study tested a combination of two drugs, T-VEC and atezolizumab, in 28 women with early-stage breast cancer that still had tumor left after standard chemotherapy. The goal was to see if this treatment could shrink or eliminate the remaining cancer before surgery. The approac…

This early-phase study tested an experimental oral drug called JAB-3312 in 40 adults with advanced solid tumors (such as lung, colon, or breast cancer) that had stopped responding to standard treatments. The main goal was to find a safe dose and understand side effects. Participa…

This study tested two different dosing schedules of the drug palbociclib combined with hormone therapy in 180 women with advanced, hormone-receptor-positive breast cancer. The goal was to see if a lower daily dose (100 mg) could control the cancer as well as the standard higher d…

This early-phase study tested a new drug called FS1502 in 161 adults with advanced solid tumors that express HER2, including HER2+ breast cancer. The goal was to check the drug's safety, find the right dose, and see if it shrinks tumors. Participants had already tried other treat…

This study tested whether adding the antibiotic moxifloxacin to standard chemotherapy improves outcomes for people with operable breast cancer. 559 participants were randomly assigned to receive either moxifloxacin or a placebo alongside their chemo. The main goal was to see if t…

This study looked at whether a program including geriatric checkups, pain management, weekly Tai Chi, and vitamin D supplements could help women over 70 with breast cancer stick to their hormone therapy. The program aimed to improve treatment compliance and reduce side effects. O…

This study tested the drug letrozole in over 5,000 women with breast cancer who had already taken tamoxifen for at least 5 years. The goal was to see if letrozole could help prevent the cancer from coming back. Participants took either letrozole or a placebo pill daily. The main …

This study looked at whether a lower starting dose (400 mg) of the drug ribociclib, combined with standard hormone therapy, is safe and effective for women with a certain type of advanced breast cancer (HR-positive, HER2-negative). The study included 376 women who had not receive…

This study tested a new combination of two drugs, samuraciclib and elacestrant, in 49 adults with a type of advanced breast cancer (HR+/HER2-). The goal was to find the right dose and see if the combination is safe and can slow cancer growth. Participants had already tried other …

This study looked at over 1,100 breast cancer patients who received a targeted dose of radiation directly to the tumor site during surgery, followed by standard radiation. The goal was to see if this approach helps prevent the cancer from coming back. The treatment was safe and e…

This early-phase study tested a personalized vaccine made from a patient's own immune cells, designed to target HER2-positive breast cancer. 31 adults with stage II or III breast cancer received the vaccine alongside standard chemotherapy before surgery. The goal was to see if th…

This study tested whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (carboplatin) helps control breast cancer that has returned on the chest wall. 76 women with hormone-resistant or triple-negative breast cancer took part. The goal was to see if the com…

This study tested whether the oral drug neratinib, alone or with other medicines, can shrink or stabilize breast cancer that has spread to the brain in people with HER2-positive disease. About 140 participants received different treatment combinations. The main goal was to see ho…

This study tested a new way to treat breast cancer that has spread to the brain. Doctors used sound waves guided by MRI to temporarily open the brain's protective barrier, allowing cancer drugs to reach the tumors. The study included 8 people with a specific type of breast cancer…

This study tested a new surgical method for women at high genetic risk of breast cancer who choose to have both breasts removed preventively and reconstructed immediately. Instead of the usual chest muscle dissection and visible breast scar, surgeons used a single-port endoscope …

This study tested whether a combination of two hormone-blocking drugs (exemestane and triptorelin) works better than the standard treatment (triptorelin and tamoxifen) for premenopausal women with hormone-sensitive breast cancer. Over 2,600 women who had surgery to remove their c…

This study tested a new treatment combination (SV-BR-1-GM plus retifanlimab) in 36 people with advanced breast cancer that had stopped responding to standard therapies. The goal was to see if the combination is safe and can shrink tumors. Participants received the treatment every…

This study tested a new drug called LY3484356 in 87 postmenopausal women with early-stage estrogen receptor-positive (ER+), HER2-negative breast cancer. The drug was given for a short time before surgery to see if it was safe and how it affected the cancer. The goal was to measur…

This study tested whether adding the immunotherapy drug atezolizumab to standard chemotherapy (bevacizumab and paclitaxel) helps people with a certain type of advanced breast cancer (HR-positive, HER2-negative). The trial included 281 participants whose cancer had spread or could…

This early-phase study tested a new approach for women with breast cancer who cannot have breast-conserving surgery. It combined a short course of high-dose radiation (CyberKnife) with standard chemotherapy drugs. The main goal was to find the safest radiation dose and check for …

This study tested whether a drug called T-DM1 causes fewer side effects than the usual treatment (paclitaxel plus trastuzumab) for people with stage I HER2-positive breast cancer. About 500 participants were randomly assigned to receive either T-DM1 or the standard combination. R…

This study tested a new way to give an extra dose of radiation (a boost) to the tumor site after standard breast radiation. Instead of multiple sessions, the CyberKnife machine delivered a single high dose very precisely, aiming to reduce skin damage and improve cosmetic results.…

This study tested a new drug called WH002 against the standard chemotherapy paclitaxel in 40 women with HER2-negative breast cancer. Both drugs were given before surgery, followed by epirubicin and cyclophosphamide. The main goal was to check safety and side effects, and also to …

This study tested a new drug called giredestrant, alone or with triptorelin, against a standard treatment (anastrozole plus triptorelin) in 231 premenopausal women with early-stage, hormone-sensitive breast cancer. The goal was to see how well the drugs slow tumor growth before s…

This study tested whether adding the experimental drug samuraciclib to the standard hormone therapy fulvestrant works better than fulvestrant alone. It involved 60 adults with a common type of advanced breast cancer (HR+/HER2-) that had worsened after prior treatment. The goal wa…

This study tested whether a combination of eribulin, pertuzumab, and trastuzumab works as well as the standard taxane-based combo for advanced HER2-positive breast cancer, but with better quality of life. 446 women who had not received chemotherapy for advanced disease took part.…

This study tested whether adding the experimental drug PF-07220060 to the standard hormone therapy letrozole works better than letrozole alone for postmenopausal women with a common type of breast cancer (HR-positive, HER2-negative). About 121 women who had not yet received treat…

This study tested a new hormone therapy pill, elacestrant, against standard treatments for people with a common type of advanced breast cancer (ER+/HER2-). The trial included 478 men and women whose cancer had worsened after previous hormone therapy. The goal was to see if elaces…

This early-stage study tested a new drug called RP903 in 69 people with advanced solid tumors (like ovarian, breast, or cervical cancer) who had no other treatment options. The main goal was to check the drug's safety and find the right dose, not to cure the cancer. While some pa…

This study tested a strong chemotherapy regimen followed by a stem cell transplant for people with stage IIIB inflammatory breast cancer. The goal was to see if this approach could improve how long patients live without the cancer coming back. 41 patients took part in this phase …

This study tested whether adding enzalutamide to the hormone therapy exemestane helps control advanced breast cancer that is hormone receptor-positive and HER2-normal. About 247 postmenopausal women who had already tried up to one prior hormone or chemotherapy took part. The main…

This study tested a combination of two drugs—pembrolizumab (an immunotherapy) and olaparib (a PARP inhibitor)—in 14 people with advanced breast cancer that has a BRCA mutation or similar DNA repair problem. The goal was to see if the combo could shrink or stabilize tumors. The ca…

This study tested whether giving higher doses of two chemotherapy drugs (epirubicin and docetaxel) along with a drug to boost immune recovery (pegfilgrastim) could safely treat women with locally advanced or inflammatory breast cancer. 93 women took part. The goal was to see how …

This study tested a three-drug combination (paclitaxel, trastuzumab, and pertuzumab) given before surgery to 23 people with a rare and aggressive type of breast cancer called inflammatory breast cancer. The goal was to see if the treatment could eliminate all signs of cancer in t…

This early-phase study tested whether giving the heart medication carvedilol to breast cancer patients at high risk for heart problems could safely protect their hearts during chemotherapy with doxorubicin and/or trastuzumab. 68 women with stage I-III breast cancer participated. …

This study tested a new drug, trastuzumab deruxtecan, against standard treatments in 608 people with advanced HER2-positive breast cancer that had already been treated with T-DM1. The goal was to see if the new drug could slow cancer growth or improve survival. Participants had c…

This study looked at 215 breast cancer patients who had chemotherapy. It compared the usual vitamin D dose with a dose tailored to each patient's vitamin D level. The goal was to see which approach better corrected vitamin D deficiency after 6 months.

This study tested an experimental drug called ARV-471, alone or with another drug (palbociclib), in 217 people with a common type of advanced breast cancer (ER+/HER2-) that had stopped responding to standard treatments. The main goals were to check safety and see if the drug shri…

This study tested whether adding a low-dose chemotherapy pill (capecitabine) to standard hormone therapy (aromatase inhibitor) helps women with a common type of advanced breast cancer live longer without the disease getting worse. 263 women who had not received prior treatment fo…

This study looked at 720 women with early-stage breast cancer who had breast-conserving surgery. They were split into two groups: one received standard daily radiation for several weeks, and the other received a shorter course of radiation (hypofractionated). The goal was to see …

This study looked at how safe and effective two targeted drugs, trastuzumab deruxtecan and sacituzumab govitecan, are for people with advanced breast cancer. Researchers reviewed medical records of 312 patients who had already tried other treatments. The goal was to see side effe…

This study tested a new drug (darsilide) combined with two hormone therapies (exemestane and goserelin) in 119 premenopausal women with a common type of breast cancer (HR+/HER2-). The goal was to see if this combination could shrink tumors before surgery, after initial chemothera…

This study tested whether adding the cholesterol-lowering drug atorvastatin to standard hormone therapy (letrozole, fulvestrant, or aromatase inhibitors) could better control advanced breast cancer. 126 women with ER-positive, HER2-negative advanced breast cancer took part. The m…

This study tested whether adding the drug ribociclib to standard hormone therapy helps slow the growth of advanced breast cancer in Chinese women. The cancer type was hormone receptor positive and HER2 negative. 327 women took part, and the main goal was to see how long the cance…

This study looked at 61 patients with BRCA-mutated, HER2-negative breast cancer at high risk of recurrence. They took LYNPARZA tablets after surgery to see how often bone marrow suppression occurred. The goal was to monitor safety in real-world use.

This study tested a specific sequence of chemotherapy drugs given before surgery to women with triple-negative breast cancer, a type that is harder to treat. The goal was to see if the treatment could completely eliminate cancer from the breast and lymph nodes. 29 women participa…

This early-phase study tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, or lung cancer) that had stopped responding to standard treatments. The drug is a nanoparticle version of SN-38, a chemotherapy agent, given by IV on days 1 a…

This study tested a new way to give radiation to people with low-risk, early-stage breast cancer after they had a lumpectomy. Instead of many sessions, it uses just three doses aimed only at the tumor area. The goal was to see if this shorter treatment is safe and well-tolerated,…

This early-stage trial tested whether adding pulsed electromagnetic fields (PEMFs) to standard chemotherapy is safe for people with breast cancer. 14 participants received the combination before surgery. The main goal was to check for side effects, not to measure how well it work…

This large study tested whether adding pertuzumab to standard chemotherapy and trastuzumab helps prevent breast cancer from returning after surgery. Over 4,800 people with HER2-positive breast cancer took part. The results showed that the three-drug combination improved the chanc…

This study tested a non-surgical treatment for breast cancer in 21 patients aged 70 and older who could not or would not have surgery. Doctors used ultrasound to guide a needle that heats and destroys the tumor, combined with hormone therapy. The goal was to see if this approach …

This early-phase study tested whether combining the immunotherapy drug atezolizumab with precise radiation (stereotactic radiosurgery) could help control triple-negative breast cancer that has spread to the brain. Only 6 people took part. The goal was to see how long the cancer s…

This study tested whether injecting a modified herpes virus (talimogene laherparepvec) directly into breast tumors, alongside standard chemotherapy before surgery, could destroy more cancer cells in people with triple negative breast cancer. The virus is designed to infect and br…

This study tested whether metformin, a common diabetes medicine, can reduce the thickening of the uterine lining caused by tamoxifen in postmenopausal women with estrogen-positive breast cancer. Sixty women who had been taking tamoxifen for at least a year were randomly assigned …

This study looked at whether a care plan led by a geriatrician and a nurse could help older adults (70+) with cancer live longer and feel better. It included 792 people with different cancers like breast, lung, or prostate. The approach was compared to usual cancer care to see if…

This study tested a new combination of three drugs given to postmenopausal women with hormone-positive breast cancer before their surgery. The goal was to see if this approach was safe and effective at shrinking tumors. The drugs work by blocking estrogen, stopping cancer growth …

This study tested whether adding an experimental drug called ganetespib to the standard hormone therapy fulvestrant could better control advanced breast cancer. It involved 50 people whose cancer had spread and was no longer responding well to standard hormone treatments. The goa…

This study tested a new ultrasound technique to tell apart two main types of breast cancer (luminal and non-luminal) without needing a tissue sample. Researchers looked at blood vessel patterns in tumors from 94 women and created a scoring tool that could help doctors choose the …

This study looked at whether an MRI can accurately rule out breast cancer in women who have abnormal nipple discharge but normal mammogram and ultrasound results. 70 women with single-pore, non-milky, non-green discharge were given an MRI. The goal was to see how often a normal M…

This study tested whether an AI program called CadAI-B dx helps doctors better detect breast cancer on ultrasound images. Sixteen doctors reviewed 797 breast ultrasound cases (350 with cancer, 447 benign) with and without the AI's help. The goal was to see if the AI improved accu…

This study looked at whether a small, portable ultrasound device can accurately tell the difference between benign (non-cancerous) and malignant (cancerous) breast lumps in women who had a positive clinical breast exam. 150 women participated, and the device's results were compar…

This study looked at how well MRI scans can measure the size of ductal carcinoma in situ (DCIS), a very early form of breast cancer. Forty women with DCIS had an MRI before surgery, and the MRI results were compared to the actual tumor size found during surgery. The goal was to s…

This study looked at whether testing for certain gene changes (methylation) in breast tissue samples can help doctors better identify cancer in breast lesions that are hard to diagnose. Over 300 women with suspicious breast lumps provided tissue samples during standard biopsies. …

This study tested a new ultrasound technique called Nonlinear Elasticity Mapping (NEM) to help tell if a breast lump is cancerous or not. Researchers measured how breast tissue stretches and compared it to biopsy results in 172 people. The goal is to provide extra information to …

This study tested an artificial intelligence (AI) system called Carebot AI MMG to see how well it can find breast lesions (like cancer) and measure breast density from mammograms. Researchers compared the AI's accuracy to that of doctors using 122 mammogram studies. The goal was …

This study tested whether a newer 3D breast X-ray (tomosynthesis) is better than standard 2D mammography at finding breast cancer early in women aged 45-74. Over 26,000 women participated. The goal was to see if the 3D method reduces the number of advanced cancers and cancers fou…

This study tested whether a high-resolution PET-CT scan of the removed breast tumor during surgery can help surgeons see if any cancer cells are left behind. About 206 women with early-stage breast cancer received a low-dose radioactive tracer before surgery, and the removed tiss…

This study tested a new handheld gamma camera (CarolIReS) to help surgeons find and remove sentinel lymph nodes in 110 women with early breast cancer. The camera was used before and during surgery to check if any nodes were missed by standard methods. The goal was to see if the c…

This study compared two imaging methods—contrast-enhanced mammography (CESM) and MRI—to see which is better at detecting breast cancer in women with suspicious breast lesions. A total of 231 women took part, and each had both scans plus a biopsy to confirm the results. The goal w…

This study tested a new blood test (liquid biopsy) to find cancer DNA in 30 women with advanced breast cancer. The goal was to see if the blood test works as well as a standard tissue biopsy to detect specific cancer markers. If successful, this could offer a less invasive way to…

This study looked at whether adding special ultrasound techniques (elastography and contrast-enhanced ultrasound) can improve detection of breast cancer spread to underarm lymph nodes. 180 women with breast cancer took part. The goal was to see if these extra scans give doctors a…

This study tested a new way to biopsy suspicious breast calcifications (tiny calcium spots) found on mammograms. The new method uses contrast dye to guide the biopsy, while the standard method uses X-ray guidance. The goal was to see which method more accurately samples the most …

This study tested a new imaging technique called restriction spectrum imaging (RSI) to see if it can detect breast cancer as well as standard breast MRI but in less time. Researchers compared RSI scans to conventional and abbreviated breast MRIs in 460 women undergoing routine sc…

This study tested a new imaging probe (TTP-ICG) that makes cancer cells glow under a special camera. After removing breast tissue or lymph nodes, doctors soaked the samples in the probe and checked for leftover cancer at the edges or in lymph nodes. The goal was to see if this me…

This study looked at whether MRI scans can detect early signs that chemotherapy is shrinking breast tumors. Sixteen women with invasive breast cancer received chemo before surgery, and their MRI results were checked after the second cycle. The goal was to see if MRI measurements …

This study tested a new, low-power microwave imaging system (Wavelia #2) to see if it can find and measure breast lumps without using radiation. 73 women with known breast abnormalities took part. The goal was to check how well the device detects both cancerous and non-cancerous …

This study looked at whether a special type of mammogram, called contrast-enhanced mammography (CEM), can be used instead of MRI to screen for breast cancer in women at high risk or with very dense breasts. About 600 women who were already recommended for yearly MRI screening too…

This study tested a new noninvasive method called SAVE that uses ultrasound to measure how breast masses move and stretch. The goal was to see if it can accurately tell benign lumps from cancerous ones without a biopsy. Researchers studied 266 women with breast lesions to compare…

This study tested whether teaching women self-massage and stretching exercises before and after breast cancer surgery could prevent chronic pain. 143 women participated, with half receiving standard care and half also attending workshops on self-massage and stretching. The goal w…

This study tested if giving a light electrical stimulation to a specific wrist point during breast cancer surgery could help prevent nausea and vomiting after the operation. Researchers enrolled 188 women at high risk for post-operative nausea. The approach combined the wrist sti…

This small pilot study tested whether an ice plant cream could prevent hand-foot syndrome—a painful skin reaction—in 15 breast cancer patients receiving chemotherapy with doxorubicin or docetaxel. The main goal was to see if a larger study is possible, not to prove the cream work…

This small early-phase study tested whether losartan, a common blood pressure medication, could prevent early signs of heart damage in 5 breast cancer patients receiving radiation therapy. The goal was to see if losartan reduces scarring in the heart muscle. The study is complete…

This study looked at two ways to manage ovarian cancer risk in 40 women with BRCA gene mutations or strong family history. One group had preventive surgery to remove ovaries and fallopian tubes, while the other group had regular CA-125 blood tests to catch cancer early. Researche…

This pilot study tested a program called ActiveHeal EST (Engage-Sustain-Triumph) to see if it helps breast and prostate cancer survivors keep doing daily activities despite challenges. Thirty adults diagnosed within the last year took part. The study measured resilience, quality …

This study tested two types of nerve blocks to control pain after breast cancer surgery (modified radical mastectomy). 32 women received one of two ultrasound-guided injections of numbing medicine. The serratus anterior plane block provided better pain relief, lasted longer, and …

This study looked at 245 women with early-stage hormone-sensitive breast cancer to see if taking their daily hormone therapy in the morning or evening made a difference in side effects and quality of life. Participants were randomly assigned to take their medication either in the…

This study tested whether a technique called ischemic preconditioning, which is used in organ transplants, could help reduce fat tissue damage after breast reconstruction surgery. The approach involves short cycles of blood flow interruption before the main surgery. The study inc…

This study tested whether watching 360° virtual reality movies can help lower fear and anxiety in cancer patients before they start radiation treatment. 292 adults with breast, lung, prostate, head and neck cancer, or brain tumors participated. Patients watched VR movies and then…

This study tested a mobile app called WeCanManage designed to help cancer survivors who have disabilities manage long-term effects of their illness and treatment. Twenty adults who had breast cancer, head and neck cancer, or sarcoma used the app and reported on their symptoms and…

This study looked at whether a supervised or distance-guided brisk walking program could help manage fatigue in breast cancer patients on hormone therapy. Seventeen women who had finished chemotherapy or radiation but still felt tired took part in a 6-week walking program. The go…

This study looked at whether a short mindfulness program before and after surgery could help women with breast cancer feel less anxious and improve their quality of life. 42 women participated, and researchers measured their emotional well-being through surveys and finger-prick b…

This study tested a program to help young couples cope with reproductive and sexual health problems after breast or gynecologic cancer. 158 survivors and their partners participated. The program aimed to improve communication and reduce distress about fertility and intimacy.

This study tested a short, nurse-led program to help breast cancer survivors who were hesitant or delayed in starting hormone therapy. The program aimed to support patients in making informed decisions. The study enrolled 35 women and measured how feasible and acceptable the prog…

This study tested whether acupuncture can reduce hot flashes in women with hormone-positive breast cancer. 84 participants were randomly assigned to receive acupuncture or standard care. The researchers tracked hot flash frequency and severity over 10 weeks to see if acupuncture …

This study tested whether starting a personalized exercise program before breast cancer surgery helps women recover better. Thirty female patients followed the program for 12 months. Researchers measured shoulder movement, pain, arm function, fatigue, and quality of life to see i…

This study looked at whether a 6-week supervised exercise program could improve quality of life and reduce fatigue in 78 adults with breast or colon cancer. Some participants were also receiving chemotherapy, radiation, or hormone therapy. The researchers measured changes in qual…

This study looked at whether self-acupressure (like acupuncture but without needles) can help reduce joint pain and stiffness caused by aromatase inhibitor therapy in postmenopausal women with breast cancer. Fifty participants learned to apply pressure to specific points on their…

This study looked at whether it's possible to test a program that combines relaxation exercises and a vaginal moisturizer to help breast cancer survivors with sexual health issues. 18 women who had finished their main cancer treatment took part. The goal was to see if women would…

This study tested whether omega-3 fatty acid supplements can reduce joint pain and stiffness caused by aromatase inhibitor therapy in postmenopausal women with hormone receptor positive breast cancer. 77 participants took omega-3 supplements soon after starting their cancer medic…

This study tested whether using a low-intensity vibration platform for 10 minutes twice a day for 12 months could improve muscle function and reduce pain in 72 early-stage breast cancer survivors starting aromatase inhibitor therapy. Participants did not exercise regularly. The g…

This study tested a treatment called extracorporeal shock wave therapy (ESWT) for people with axillary web syndrome, a common complication after breast cancer surgery that causes pain and limited arm movement. Twenty patients who had breast cancer surgery and developed this condi…

This study tested a new web-based dance movement therapy program for women with breast cancer. The goal was to see if it could help with emotional awareness (alexithymia) and reduce frailty. Sixty-seven women participated, with some doing the dance program and others receiving st…

This study looked at whether a single shot of numbing medicine near the ribs (called a rhomboid intercostal block) can lower the chance of long-term pain after breast cancer surgery. 254 women having mastectomy were split into two groups: one got the block, the other did not. Res…

This study tested an 8-week virtual program called HEAL that teaches healthy eating and active living to breast cancer survivors. 22 adults who had breast cancer took part in weekly 90-minute sessions. Researchers measured stress, diet, and quality of life before, after, and up t…

This small study tested whether taking fat from one part of the body and moving it to a breast that was damaged by radiation could improve skin health. Ten women who had radiation for breast cancer took part. The goal was to see if this fat transfer could make the skin softer and…

This study tested whether a hand massage before inserting an IV can help breast cancer patients receiving chemotherapy. Sixty women were split into two groups: one got a hand massage before the IV, the other did not. Researchers measured how quickly the IV was placed, and how anx…

This study looked at two different radiation schedules for women with early-stage breast cancer after breast-conserving surgery. One group received a very short course of radiation over 1 week, while the other received a slightly longer course over 3 weeks. The goal was to compar…

This study looked at whether a 12-week exercise program could improve body composition (like fat and muscle mass) and physical function in breast cancer patients. 62 women who were recently diagnosed and possibly still undergoing treatment took part. The goal was to see if exerci…

This study tested a precise radiation method called multi-beam IMRT in 100 women with breast cancer who had implant reconstruction after mastectomy. The goal was to see if this technique lowers the chance of implant failure and other side effects compared to standard radiation. B…

This pilot study looked at whether cognitive behavioral therapy for insomnia (CBT-I) could help breast cancer survivors take their daily hormone therapy pills more consistently. 35 women who had trouble sleeping and sometimes missed their medication took part. The goal was to see…

This study looked at whether myofascial release exercises (a type of gentle stretching) can help breast cancer patients who have had radiation therapy. The goal was to see if these exercises reduce muscle tightness, pain, and improve shoulder movement. Thirty patients participate…

This study tested whether a shorter course of proton therapy (15 sessions) is as safe as the standard longer course (25 sessions) for women who had a mastectomy for breast cancer and need radiation to nearby lymph nodes. 88 women participated. The goal was to see if the shorter s…

This study tested a virtual reality program to help breast cancer patients who have memory or concentration problems after treatment. 23 patients used the program for 10-15 minutes each week for 6 weeks. The goal was to see if patients would stick with the program and if it could…

This study tested whether giving a lower dose of the steroid dexamethasone before the chemotherapy drug docetaxel is safe for people with breast or prostate cancer. The goal was to see if a reduced dose could still prevent allergic reactions and fluid buildup while causing fewer …

This early-phase study tested the safety of adding the drug rucaparib to standard radiation therapy for women with triple negative breast cancer who still had cancer after chemotherapy. The study involved 31 women and aimed to find the best dose that causes the fewest side effect…

This study tested a breast reconstruction method that uses only a patient's own fat (lipomodulin) instead of implants or tissue flaps. It included 118 women who had a mastectomy for breast cancer. The goal was to see how well the technique works, how the breast looks afterward, a…

This study tested whether using robotic tools for nipple-sparing mastectomy and immediate breast reconstruction leads to higher patient satisfaction compared to standard open surgery. About 82 women with breast cancer or high genetic risk took part. The goal was to see if the rob…

This study tested a group video app that guides breast cancer survivors through yogic breathing exercises at home. The goal was to see if the app helps reduce stress and other long-term health issues after cancer treatment. Forty survivors who finished radiation therapy within th…

This study tested whether adding two supportive drugs (loperamide for diarrhea and G-CSF for low white blood cells) could make a common chemotherapy drug, sacituzumab govitecan, easier to tolerate. It involved 50 adults with advanced triple-negative or luminal breast cancer that …

This study tested whether a web-based exercise program could reduce nerve pain (peripheral neuropathy) and improve quality of life in 90 breast cancer patients receiving taxane chemotherapy. Participants followed an 8-week online exercise plan designed by a physiotherapist. The g…

This study tested a food supplement (Tenflex) containing collagen and chondroitin sulfate to see if it could reduce joint and muscle pain in 30 women with hormone-positive breast cancer. All participants were on aromatase inhibitor therapy and had pain for less than 6 months. The…

This study tested whether an ultrasound-guided PECS nerve block could reduce opioid use and improve pain control in 70 women undergoing breast cancer surgery. Participants received either the nerve block or standard care. The goal was to see if the block could lower the need for …

This study tested an online group program to help breast cancer survivors manage ongoing pain. Twenty-three participants attended weekly one-hour sessions for six weeks and filled out questionnaires before and after. The goal was to see if the program could reduce pain interferen…

This study tested a personalized cognitive training program to help breast cancer patients manage chemobrain—memory and thinking problems caused by chemotherapy. Fifty women with newly diagnosed breast cancer took part, with half receiving the training and half getting only an ed…

This study looked at whether the MyChart app can help collect information about hot flashes in breast cancer patients. About 56 people took part to see if using the app is practical for tracking symptoms and treatments. The goal is to find better ways to manage hot flashes withou…

This study looked at whether a traditional Chinese mind-body exercise called Dao-yin can improve sleep, quality of life, and overall well-being in breast cancer patients who had surgery and are receiving chemotherapy. About 150 women participated, with some doing daily 20-minute …

This study tested a mobile health program that teaches pain coping skills to breast cancer patients in underserved areas. 180 women with persistent pain joined video sessions with a therapist and used simple mobile tools at home. The goal was to see if this approach could reduce …

This study looked at whether giving a painkiller called tapentadol before breast cancer surgery could lower the amount of morphine needed during and right after the operation. 70 patients took part, and researchers measured how much morphine they used. The goal was to see if pre-…

This study tested a digital information tool called Digi-Do for breast cancer patients undergoing radiotherapy. The goal was to help patients feel more involved and prepared before, during, and after treatment. Researchers measured changes in distress and self-confidence in 80 pa…

This study looked at whether craniosacral therapy (CST), a very gentle hands-on technique, can help women who have finished breast cancer treatment feel better. 102 women were split into three groups: one received one-on-one CST sessions, one learned CST self-help techniques in a…

This study tested whether a mobile app could help women with early breast cancer follow their treatment plans and feel better. 540 women were split into two groups: one used the app for reminders and tips, the other had standard follow-up. The goal was to see if the app improved …

This study looked at whether a tailored exercise program could help with memory, focus, and overall well-being in women treated for locally advanced breast cancer. 37 women who had chemotherapy and reported thinking problems took part. The goal was to see if exercise improved the…

This study tested whether a combination of virtual reality (VR) and music can help breast cancer patients feel less anxious, have less pain, and enjoy a better quality of life during chemotherapy. Sixty patients were offered VR and music during their chemo sessions. The main goal…

This study tested a mobile app designed to help women manage lymphedema (arm swelling) and improve their quality of life after breast cancer surgery. Sixty women who had breast-conserving surgery or lymph node removal used the app for education, exercises, and symptom tracking. T…

This study looked at whether Coenzyme Q10, a natural supplement, can help prevent or lessen the side effects of chemotherapy in women with breast cancer. Forty women who had not yet started chemo took part. The goal was to see if CoQ10 could reduce problems like fatigue, nerve pa…

This study looked at whether taking Coenzyme Q10 supplements can reduce nerve pain, fatigue, and other side effects in women with newly diagnosed breast cancer who are receiving paclitaxel chemotherapy. Fifty women took either Coenzyme Q10 with their chemo or chemo alone for 12 w…

This study tested whether technology-based rehab (like smartphone apps or video calls) can help women regain arm and shoulder movement after breast cancer surgery. 45 women who had surgery with lymph node removal used either supervised exercise, a telerehab program, or a mobile a…

This study tested whether a noninvasive device that gently stimulates a nerve in the ear (taVNS) could help improve sleep in people with stage I-IV breast cancer. Twenty participants completed the trial, and researchers measured how practical and acceptable the treatment was. The…

This study looked at 96 women having breast-conserving surgery for cancer. It compared recovery quality between those who got a nerve block (PECS) and those who had general anesthesia. The goal was to see if the nerve block leads to less pain, fewer side effects, and a smoother r…

This study tested whether a yoga program done at home and in class is practical for breast cancer patients on hormone therapy who have joint pain. 24 women took part, doing daily yoga poses and attending group sessions. The goal was to see if they would stick with the program and…

This study tested whether a mobile app exercise program is practical and helpful for women with breast cancer undergoing chemotherapy. 32 women participated. The program included guided exercises and education delivered through the app. Researchers measured how many women stuck w…

This study tested two ways to mark small, non-palpable breast tumors before surgery: a tiny radioactive seed (iodine-125) versus a standard metal wire. 350 women with early-stage breast cancer took part. The goal was to see if the seed method helps surgeons remove the tumor compl…

This study tested whether adding ketamine to general anesthesia could reduce the need for morphine and lessen pain after breast cancer surgery. About 230 adults having a mastectomy or lumpectomy took part. The goal was to see if ketamine helps control post-operative pain and lowe…

This study tested whether using e-health tools—like a smartphone app or a phone consultation—could help women manage pain and anxiety after a breast biopsy. About 193 women took part. The goal was to see if these tools, which let patients report their symptoms and get quick help …

This study tested whether a special dressing (Hydrosorb) is better than a water-based spray at managing skin irritation from radiation therapy in 278 women with breast cancer. The goal was to prevent skin damage from getting worse and avoid interruptions in radiation treatment. P…

This study tested a program called PRISM, designed to help women with breast cancer build resilience through skills like stress management, goal-setting, and positive thinking. 43 women participated, including those with early-stage or metastatic breast cancer. The goal was to se…

This study tested whether starting physical therapy and learning about side effects before breast cancer treatment could help prevent problems like joint pain, muscle weakness, and fatigue. 75 newly diagnosed patients took part. Some received extra education and physical therapy,…

This study looked at whether combining an 8-week mindfulness-based stress reduction program with endurance exercise training can help women with breast cancer feel better and improve their physical fitness. Researchers measured changes in exercise capacity, quality of life, and b…

This study tested a special surgical glue called Ifabond in 104 breast cancer patients having partial mastectomy. The goal was to see if the glue reduces seroma—painful fluid collections that can form after surgery. Patients were randomly assigned to get the glue or standard care…

This study tested whether a special physiotherapy program that combines exercises with dry needling and nerve techniques works better than exercise alone for women with long-term shoulder pain after breast cancer treatment. 90 women took part. The goal was to reduce pain and impr…

This study tested a simple, drug-free approach to help women feel less anxious before breast or gynecologic cancer surgery. Participants practiced a guided breathing technique (cardiac coherence) combined with a hypnosis session for one week before their operation. The main goal …

This study tested a special light helmet for women with breast cancer who lost hair after chemotherapy. The helmet uses low-level light to help hair grow back faster and thicker. Researchers measured hair count, hair width, and how the women felt about their hair loss. The goal w…

This study tested whether auriculotherapy (a type of ear acupuncture) can reduce joint and muscle pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. About 197 women with breast cancer who had pain from their medication were randomly assigned to recei…

This study tested whether wearing special cold caps (Penguin caps) during chemotherapy could prevent or reduce hair loss in people with early-stage breast cancer. Twelve participants used the caps while getting one of four common chemo regimens. The main goal was to see how many …

This study looked at whether using telemedicine (video calls), connected watches, and symptom tracking apps can help women with advanced breast cancer who live far from their cancer center. Fifteen women took part, and researchers measured their quality of life after 6 and 12 mon…

This study looked at whether giving the antidepressant mirtazapine before and after mastectomy surgery can reduce pain. 62 women scheduled for mastectomy took part. The main goal was to see if it lowered the amount of morphine needed in the first 24 hours and improved pain scores…

This study tested whether a special gel (Oleogel-S10) helps heal skin burns caused by radiation therapy in breast cancer patients. The gel was used together with a standard steroid cream. The study included 18 adults with stage I-IV breast cancer who developed moderate to severe …

This study tested a shorter, more focused radiation schedule for people with early-stage breast cancer after surgery. The goal was to see if this approach causes fewer skin side effects. 35 participants received the treatment, and researchers tracked any skin reactions and checke…

This study looked at whether physical therapy can improve arm, shoulder, and hand problems that some people develop after breast cancer surgery. It involved 135 women and men who had surgery to remove breast cancer and at least one lymph node. The goal was to see if therapy helps…

This pilot study tested an online program called THRIVE, designed to help breast cancer survivors feel more positive and less upset about taking their daily hormone therapy (endocrine therapy). The goal was to see if the program was acceptable and feasible for women who had finis…

This study tested if adding ketamine or magnesium sulfate to a standard numbing injection (nerve block) could better control pain after breast cancer surgery. It involved 60 women and measured how much morphine they needed for pain relief in the first two days after their operati…

This study aimed to find the most effective way to deliver pain-numbing medication (nerve blocks) before a double mastectomy with reconstruction. Researchers compared different injection locations to see which one best reduced patients' need for opioid painkillers after surgery. …

This study tested a social platform called MammoChat where people who had breast cancer imaging could share experiences anonymously. Researchers measured anxiety levels and collected de-identified images to train AI for better detection. 199 adults who had a breast imaging test i…

This study looked at whether it is possible to measure certain cholesterol-related substances, called oxysterols, in the blood of women with breast cancer who are taking hormone therapy like tamoxifen or aromatase inhibitors. The goal was to see if these measurements could help u…

This study tested a special clinic for women who finished treatment for early-stage breast or gynecologic cancer. The clinic used online surveys to track symptoms and connect patients with nurses or dietitians when needed. The goal was to see if this approach is practical and hel…

This study looked at data from 298 breast cancer patients to create a computer model that predicts whether chemotherapy before surgery will completely eliminate the cancer. The model uses routine medical information like tumor details and lab results to give doctors a personalize…

This early study tested a new device that detects light signals during breast cancer surgery to help surgeons know if they are cutting through cancer or healthy tissue. 24 women with invasive breast cancer took part. The main goal was to check safety and see if the device works w…

This study reviewed medical records of 405 adults in Egypt with advanced HER2-negative breast cancer to find out how many actually have a subtype called HER2-low. Researchers looked at past test results to count cases and describe patient characteristics. The goal was to better u…

This study observed over 2,400 women in Russia with a certain type of advanced breast cancer (HR+/HER2-). Researchers tracked which treatments doctors chose (like ribociclib, alpelisib, hormone therapy, or chemo) and how long they worked before needing a change. The goal was to u…

This study created and tested a short questionnaire to measure how well women accept having breast cancer. Researchers asked 101 women to fill out the survey to see if it reliably captures two key aspects: being open to cancer-related thoughts and feelings, and staying active des…

This study looked at how a gelatin capsule containing American ginseng root extract affects certain markers in breast cancer tumors and nearby healthy breast tissue. Sixteen women with breast cancer took the extract for 10-14 days before their surgery. Researchers measured change…

This study checked if a blue dye called methylene blue, which is often used to find lymph nodes during breast cancer surgery, affects blood pressure and heart rate while patients are under anesthesia. Researchers compared 220 women who got the dye with those who did not. The goal…

This study looked at 172 breast cancer patients to see how proton or photon radiation affects the heart. Researchers measured heart function and blood markers before, during, and up to one year after treatment. The goal was to understand which type of radiation might cause less h…

This study tested a new way to help breast cancer patients who also have diabetes or prediabetes. Researchers split 74 patients into two groups: one group worked with a nurse trained in diabetes care, while the other did not. The goal was to see if having a diabetes nurse as part…

This study tested whether sending reminders (nudges) to doctors, patients, or both could increase the number of women with extremely dense breasts who get a breast MRI. Over 1,300 women aged 40-74 took part. The goal was to see if these nudges work and if the effect differs betwe…

This study looked at 50 women with breast cancer who had a lumpectomy. Researchers compared two types of anesthesia—general anesthesia and a nerve block called PECS—to see how each affected white blood cell counts before and after surgery. The goal was to learn if the choice of a…

This study looked at how breast cancer treatment affects sexual health in 25 women with non-metastatic breast cancer. Participants filled out anonymous questionnaires about their sexual function, quality of life, and emotional well-being before and after chemotherapy. The goal wa…

This study tested two ways to help White Mountain Apache women get mammograms. 323 women were randomly assigned to either a culturally tailored education program or that same program plus a personal health coach. The goal was to see which approach led to more women getting screen…

This study reviewed medical records of 693 Japanese patients with a certain type of advanced breast cancer (HR+/HER2-) who received palbociclib plus hormone therapy as their first or second treatment. Researchers wanted to see how long patients lived without the cancer getting wo…

This study looked at whether eating only during an 8-hour period each day (time-restricted feeding) changes certain blood markers linked to breast cancer risk in postmenopausal women with pre-diabetes. 29 women were randomly assigned to either an 8-hour eating window or a 12-hour…

This study looked at whether the sentinel lymph node technique (a way to check if cancer has spread) works in women who have more than one tumor in the same breast (multifocal breast cancer). 216 women with early-stage, invasive breast cancer that had not spread to the lymph node…

This study looked at how different hormone therapies for breast cancer affect memory in postmenopausal women. 44 women were randomly assigned to take either an aromatase inhibitor (letrozole, anastrozole, or exemestane) or tamoxifen. Researchers tested memory and thinking skills …

This study looked at how the breast cancer drug tamoxifen interacts with certain proteins inside tumor cells. Researchers studied 59 women with a common type of breast cancer to better understand why some tumors respond to tamoxifen and others do not. The goal is to use this know…

This study tested a digital tool (a chatbot) to help cancer survivors learn about genetic testing for hereditary cancer risk. 50 adults who had certain cancers (like breast, ovarian, or prostate) took part. The goal was to see if the chatbot was easy to use and if it helped more …

This study looked at how Mexican-American families discuss their risk for diabetes, heart disease, breast cancer, and colon cancer. Researchers interviewed 498 adults from the same households to understand how culture and family ties help or hinder these conversations. The goal i…

This study analyzed medical records from 779 Medicare patients aged 65 and older with a specific type of advanced breast cancer (HR+/HER2-). It compared survival between those who received a combination of palbociclib and an aromatase inhibitor (AI) versus those who received an A…

This study tested a new device called the EnVisio SmartClip that helps doctors locate breast tumors during surgery. Fifty people with breast cancer took part. The goal was to see if the SmartClip makes it easier for radiologists and surgeons to find and remove the right tissue.

This study tested a device that measures pain signals during breast surgery to see if a pain block (paravertebral block) is working. It involved 100 women having a mastectomy. The goal was to improve pain control and reduce the need for extra pain medicine.

This study tested whether a newer type of PET scan (68Ga-FAPI) can better predict how well breast cancer responds to chemotherapy before surgery, compared to standard PET and MRI scans. Twenty-seven women with breast cancer had all three scans before and after chemotherapy. The r…

This study tested whether an AI-assisted software (iCurveE) helps doctors more accurately and quickly outline organs at risk on CT scans for radiation therapy. 500 adults with lung, breast, or esophageal cancer participated. Researchers compared manual contouring, AI-only, and AI…

This study looks at better ways to measure how irregularly shaped tumors respond to treatment before surgery. Researchers compared a new 3D method (TDTP-RECIST) with the standard approach (RECIST 1.1) using past scans from 120 adults with breast, pancreatic, or biliary cancers. T…

This study tested a combination of chemotherapy (nab-paclitaxel) and immunotherapy (pembrolizumab) in 32 people with hormone receptor-positive breast cancer. The goal was to see how the treatment changed a biomarker called PD-L1 in tumor tissue. Results help researchers understan…

This study looked at over 4,400 women to see if how breast cancer is found (by routine screening or because of symptoms) affects quality of life years later. Researchers compared side effects and well-being between these groups and also against women without breast cancer. The go…

This study looked at whether certain anesthesia drugs might stress the heart in breast cancer patients who had prior chemotherapy with anthracyclines (a type of chemo known to affect the heart). Researchers measured a heart stress marker called BNP before, during, and after surge…

This study looked at 171 women with early breast cancer to see if immune cells inside tumors are linked to how well chemotherapy works. Researchers also checked if these immune markers relate to cancer DNA in the blood. The goal is to better understand which patients might respon…

This study tested whether automated planning tools can be used with MR images to guide radiation therapy for breast cancer. The goal was to make treatment faster and more precise without extra radiation exposure. 63 female breast cancer patients participated. The research focused…

This study looked at how people with brain tumors or breast cancer perceive their own memory, especially the ability to remember to do things in the future (like taking medication). Over 400 participants completed questionnaires about memory, mood, and fatigue. The goal was to un…

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to use a mobile website, receive two motivational coaching calls, o…

This study involved 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers wanted to see how different surgical and radiation techniques affect breast firmness (fibrosis) and cosmetic outcome. The goal was to find ways to improve appearance and q…

This study looked at medical records of over 218,000 adults in England with a common type of breast cancer (HR+/HER2-). Researchers tracked which treatments patients received, how the disease progressed over time, and how healthcare resources were used. The goal was to better und…

This study looked at whether aromatase inhibitors, a common hormone therapy for breast cancer, affect balance and increase fall risk in postmenopausal women. Researchers compared 76 women who had taken the drug for at least a year with those who had never taken it. They used spec…

This study followed 562 premenopausal women in China with hormone receptor-positive breast cancer who received a GnRHa injection to suppress ovarian function after surgery. Researchers measured quality of life and how well patients followed their treatment plan using questionnair…

This study looked at 36 people having breast cancer surgery to see how well different numbing techniques block pain. Researchers mapped the numb areas on the skin to find which method covers the surgical cut best. The goal is to help doctors choose the right numbing approach for …

This study reviewed medical records of women with advanced or metastatic HR+/HER2- breast cancer who were treated with palbociclib plus an aromatase inhibitor or fulvestrant in community clinics. The goal was to understand real-world treatment patterns, how long patients stayed o…

This study tested whether breast cancer has a unique smell that can be detected by a special sensor. Researchers collected odor samples from the hands of 35 women with breast cancer before and after their tumor was removed. The goal was to see if the sensor could identify cancer-…

This study aimed to find protein patterns (proteomic signatures) in tumor samples and blood that could predict how well breast cancer responds to chemotherapy given before surgery. Researchers analyzed samples from 66 women with breast cancer who had not received chemotherapy bef…

This study tested a new type of CT scanner that takes pictures during radiation therapy for lung, liver, breast, and other cancers. The goal was to see if the new scanner produces clearer images with fewer distortions. 31 people participated, and the results will help doctors bet…

This study looked at whether sending text message reminders could boost the number of people who complete colorectal and breast cancer screening. Over 44,000 eligible adults participated. The goal was to see if simple SMS reminders are more effective than standard letters alone, …

This study looked at whether an artificial intelligence program could effectively provide genetic counseling to women newly diagnosed with breast cancer who do not meet current guidelines for genetic testing. Researchers compared the AI approach to traditional in-person counselin…

This study looked at whether women aged 50 to 74 getting a routine mammogram for breast cancer screening would also agree to a quick hepatitis C test. The goal was to find undiagnosed hepatitis C cases and connect those women to care. About 1,500 women took part, and the study me…

This study looked at whether a genetic condition called DPD deficiency can predict severe side effects from the chemotherapy drug capecitabine in women with metastatic breast cancer. Researchers analyzed blood samples from 303 participants to see if those with the deficiency had …

This study looked at how closely 200 patients with advanced breast or prostate cancer follow their prescribed oral medication routines. Participants filled out questionnaires about their pill-taking and gave blood samples to check certain health markers. The goal was to understan…

This early-stage study tested the safety of a new drug called Orialpha (BD-C) in 15 healthy adults aged 18 to 60. Researchers looked for side effects and the highest safe dose. The goal was not to treat disease but to gather safety information for future studies.

This study looked back at medical records of over 500 women in Gulf countries with advanced breast cancer that was previously labeled as HER2-negative. Researchers re-tested old tumor samples to find out how many actually had a newer subtype called HER2-low. The goal was to bette…

This study looked at how women ages 39-49 react to scientific information about mammography's benefits and harms. Researchers measured feelings like disbelief, distrust, and thinking the information doesn't apply to them. The goal was to understand what drives women's decisions a…

This study tested a new automated method to grow cancer cells from patients with metastatic cancers (like prostate, breast, lung) inside chicken eggs. The goal was to see if this system could successfully grow tumors from patient samples, which could help doctors study cancer and…

This study looked at whether adding osteopathic manipulative medicine (OMM) to standard breast massage helps more dye and radioactive tracer reach the lymph nodes during breast cancer surgery. 27 women having breast-conserving surgery and sentinel lymph node biopsy took part. The…

This study looked at how chemotherapy given before breast cancer surgery (neoadjuvant chemotherapy) affects physical abilities like muscle strength, balance, and fatigue. Researchers measured these functions in 67 women before and after chemotherapy. The goal was to understand th…

This study looked at 93 women with breast cancer who had a lumpectomy and then received a special type of radiation called simultaneous integrated boost (SIB). The goal was to track any short-term and long-term side effects from this radiation approach. Researchers compared their…

This study looked at whether a low-dose vaginal estrogen tablet (Vagifem) is safe for women who have had breast cancer and are taking hormone-blocking drugs called aromatase inhibitors. 31 postmenopausal women with a history of breast cancer used the tablet for vaginal dryness, a…

This study looked at 1,571 women with early-stage HER2-positive or triple-negative breast cancer who had no signs of cancer in their lymph nodes on ultrasound. Researchers wanted to see how often cancer actually spread to the lymph nodes after breast-conserving surgery. The goal …

This study looked at 200 early-stage breast cancer patients receiving trastuzumab, a drug that can rarely cause heart damage. Researchers compared two standard schedules for monitoring heart function to see which works better. The goal was to find the safest and most effective wa…

This study tested a program called KanSurvive-ECHO to help rural primary care clinics provide better follow-up care for cancer survivors. Researchers worked with 15 clinics to improve tasks like scheduling cancer screenings, checking for distress, and tracking weight and tobacco …

This study looked at what happens in the skin when breast cancer patients get radiation therapy. Researchers took small skin samples from 20 patients to understand why some people get itchy, red, or swollen skin. The goal is to find better ways to prevent or treat these skin reac…

This study looked at how physical fitness, daily activity, and sitting time relate to insulin resistance (a diabetes risk factor) in 40 breast cancer survivors taking hormone therapy. Participants completed fitness tests, body scans, and wore activity monitors. The goal was to un…

This study looked at whether teaching women in prison about breast cancer helps them understand it better. Forty women took part and answered questions before and after the lessons. The results showed that the education improved their knowledge and awareness of breast cancer.

This study tested a community-based program to help homeless women get mammograms and overcome barriers to breast cancer screening. Researchers worked with 203 women living in shelters or transitional housing to see if education and support could increase screening rates. The goa…

This study tested whether artificial intelligence (AI) can improve mammography screening for breast cancer. Over 100,000 women took part. The goal was to see if AI could help radiologists find cancers more accurately and reduce false alarms compared to the standard method of two …

This study analyzed blood samples from breast cancer patients to find genetic markers that might predict how well they respond to chemotherapy. Researchers focused on patients who received common chemo drugs like anthracyclines or taxanes. The goal was to better understand why so…

This study looked at 236 adults with breast, pancreatic, or colorectal cancer who came to the University of Colorado for a second opinion. Researchers wanted to understand what factors, like patient background or disease type, influence whether someone decides to stay at the new …

This study tested a program for older adults (ages 65-90) who had breast, colorectal, or prostate cancer. A community health worker assessed their health and provided coaching to address issues often missed after cancer treatment. The goal was to see if this approach is feasible …

This study looked at why some breast cancer treatments stop working over time. Researchers took tumor samples from 269 patients whose cancer had returned or worsened after targeted therapy. By studying genetic changes and protein activity in the tumors, they hope to uncover how r…

This study followed 830 women who finished treatment for early or locally advanced breast cancer (but not yet metastatic). Researchers used questionnaires to measure quality of life, including physical, emotional, and sexual health. The goal was to understand how survivors feel a…

This study looked at whether using a special ultrasound ruler during breast-conserving surgery helps surgeons remove all cancer the first time. Researchers reviewed records from 273 breast cancer patients. The goal was to see if this technique lowers the chance of needing a secon…

This study looked at over 2,600 women in Germany with a common type of advanced breast cancer (HR+/HER2-). Researchers observed how long the cancer stayed under control when women received one of three first treatments: a combination of ribociclib plus hormone therapy, hormone th…

This study observed 120 women having mastectomy for breast cancer to see if the gender of their anesthesiologist and the type of pain relief used affected their pain levels and need for painkillers after surgery. Researchers measured pain at several points in the first 24 hours a…

This study looked at how women aged 39 to 49 make decisions about mammography screening after reading a guide that explains both the benefits and harms. About 500 women completed surveys over a year to share their thoughts, intentions, and whether they actually got screened. The …

This study tested a website designed to help primary care doctors and women aged 75 to 89 talk about the pros and cons of mammograms. The goal was to see if the tool helped women make clearer decisions about screening. 155 participants took part, and the study measured their scre…

This study aimed to find out what prevents low-income and minority breast cancer patients from getting genomic testing. Over 500 patients in Northern California completed a survey and some did phone interviews. The goal was to identify barriers so that future policies can make te…

This study looked at how breast cancer affects the quality of life of young women (under 45) and their life partners. Researchers interviewed 171 couples to understand their experiences and create a questionnaire that helps doctors better assess and support couples facing breast …

This study looked at 422 breast cancer patients to understand how their knowledge about exercise, their current activity level, and their fatigue affect their beliefs about physical activity and their desire to be active. The goal was to learn what influences their motivation, no…

This study was done in India to learn more about a gene change called PIK3CA in people with a specific type of advanced breast cancer (HR-positive, HER2-negative). It also looked at how well the drug alpelisib worked for those with the gene change. About 595 people took part, but…

This study checked if the drug olaparib, used for advanced ovarian or breast cancer, leads to low folate (folic acid) levels in the blood. Ten postmenopausal women were followed to see how many developed folate deficiency and when it happened. The goal was to understand a possibl…

This study looked back at medical records of 42 Japanese patients with a type of advanced breast cancer (HR+/HER2-). All patients had previously taken the drugs palbociclib and letrozole in an earlier study. The goal was to see how long they lived overall, without giving any new …

This study compared two ways of giving information to young women (ages 18-40) newly diagnosed with breast cancer who haven't started treatment yet. One group received standard face-to-face advice about preserving fertility, while the other used an online decision support tool be…

This study looked at 70 breast cancer survivors to see how their physical activity levels relate to heart disease risk. Participants wore a special armband to track activity and had their heart risk scored. The goal was to gather information on whether staying active can help pro…

This study tested a new type of CT scanner that takes pictures while patients lie on the treatment couch during radiation therapy for cancer. The goal was to see if the images were clear enough to help doctors aim radiation more precisely. 41 adults with head and neck, lung, brea…

This study reviewed medical records of 111 adults with early-stage HER2-positive breast cancer who received the drug neratinib as extra treatment after their main therapy, through a special early access program in Europe. The goal was to describe the patients' ages, genders, heal…

This study tested a mobile health app designed to help Black women with breast cancer learn about and join clinical trials. Researchers worked with 80 participants to see if the app was easy to use and helpful. The goal was to understand how well the app fits into clinic routines…

This study looked at how a common chemotherapy drug called 5-FU affects small blood vessels in cancer patients. Researchers measured blood flow in the skin of 62 people, including current and past 5-FU patients, those on other chemotherapies, and healthy volunteers. The goal was …

This study reviewed medical records of about 1,669 adults with HER2-low advanced breast cancer in Russia to understand how doctors diagnose and treat this type of cancer in everyday practice. Researchers looked at patient characteristics, treatment choices, and outcomes from 2021…

This study looked at how well CDK4/6 inhibitors (a type of targeted therapy) work for people with advanced breast cancer in everyday medical practice in Egypt. Researchers tracked 206 patients to see how long the treatment kept cancer from growing, its side effects, and its cost-…

This pilot study looked at whether a patient navigator could help Black breast and prostate cancer patients complete a shorter course of radiation therapy. The study enrolled 30 African-American adults with these cancers. Researchers used surveys to understand barriers to care an…

This study tested a new questionnaire to measure quality of life in young women (under 45) with non-metastatic breast cancer and their partners. Over 1000 couples participated by filling out surveys at home. The goal was to see if the questionnaire accurately captures their well-…

This study used functional MRI (fMRI) to see how the brain responds to touch on a reconstructed breast compared to the natural one. Researchers enrolled 49 women who had breast reconstruction after mastectomy. The goal was to understand how the brain's sensory map changes after s…

This study looked at spinal fluid from 7 women with breast cancer that may have spread to the lining of the brain. Researchers wanted to see if proteins in the fluid could help diagnose this condition. The goal was to learn more about the disease, not to test a treatment.

This study looked at whether a 6-week personalized psychological intervention could reduce distress and change gene activity linked to cancer spread in women with early-stage breast cancer undergoing surgery. Forty women participated, with half receiving the psychological program…

This study looked at new ways to find breast cancer early in 200 women aged 25-55 who have a high genetic risk due to BRCA1 or BRCA2 gene changes. Participants had annual mammograms, MRIs, and breast duct lavage over 3 years to compare imaging and cell samples. The goal was to im…

This study looked at how to better screen for breast cancer using simple physical exams in primary health clinics in Soweto, South Africa. Researchers worked with clinic staff and health officials to find out what makes screening easy or hard. The goal was to create a practical p…

This study measured the lengths of the index and ring fingers in 132 women (79 with breast cancer and 53 healthy) to see if the 2D:4D ratio is linked to cancer. Researchers also checked tumor markers in the blood. The goal was to explore whether finger patterns could serve as a s…

This study looked at 110 breast cancer patients to see if arm swelling (lymphedema) is linked to a specific type of muscle pain called myofascial pain syndrome. Researchers measured tender spots in the muscles and compared pain levels between affected and unaffected arms. The goa…

This study looked at 20 breast cancer patients with advanced lymph node involvement to see if a less extensive surgery (targeted axillary dissection) could accurately tell if cancer remained after chemotherapy. The goal was to find out if removing fewer lymph nodes is safe and re…

This study reviewed medical records of over 1,100 people with advanced breast cancer in Japan to see how they were treated with the drug palbociclib. Researchers looked at how often patients had blood tests and how long they stayed on the drug. The goal was to understand real-wor…

This study looked back at the records of 471 women who had breast cancer surgery with immediate breast reconstruction. It compared a newer method using a tiny camera through small cuts (endoscopic surgery) to the traditional method with a larger cut. The goal was to see which app…

This study looked at 77 women with breast lesions that only show up on special contrast-enhanced mammograms. Doctors wanted to find out the smallest number of tissue samples needed to make a reliable diagnosis. The goal is to make biopsies more efficient and reduce discomfort whi…

This study looked at how much money to give women with breast cancer to cover costs from being in a clinical trial. 33 women got monthly payments, and researchers checked if the amount helped reduce their financial worry. They also asked patients what they thought about getting p…

This study looked at 28 women with breast cancer that had spread to their bones. The goal was to see if two types of scans—PET-CT and whole-body MRI—agree on whether the bone tumors are getting better, worse, or staying the same during treatment. The findings could help doctors c…

This study looked at whether a personalized meal plan with more omega-3 fatty acids (found in fish) could help breast cancer survivors manage symptoms like fatigue, pain, depression, and sleep problems. Researchers worked with 98 women who had finished treatment for early-stage b…

This study looked at whether a special, quick form of genetic counseling (using charts and graphs) helps newly diagnosed breast cancer patients make more informed decisions about surgery. About 400 patients took part. The goal was to see if this method changes how patients unders…

This study looked at whether a simple blood test can predict which patients will have long-term side effects from radiation therapy. Researchers measured how well certain immune cells die after radiation in 885 people with breast or prostate cancer. The goal was to see if this te…

This study looked at why women aged 65 and older with early-stage breast cancer chose one of three options after surgery: standard weeks-long radiation, a single dose during surgery, or no radiation at all. Researchers surveyed 104 patients to understand their reasons and experie…

This study looked at how breast cancer treatment affects women's sexual well-being and what kind of educational resources they want. Researchers surveyed 93 women to understand their needs and preferences. The goal is to create better educational materials to help women manage se…

This study tested a program called REASSURE to help low-risk breast cancer survivors feel more prepared for their follow-up care. About 104 survivors took part for up to 18 months. The program aimed to reduce unnecessary visits while boosting confidence and readiness for life aft…

This study looked at whether a home body water analyzer can help detect lymphedema early in women treated for breast cancer. Lymphedema is a common side effect causing arm swelling, and early detection is key to reversing it. Researchers followed 52 women for a year, having them …

This study looked at 300 breast cancer patients who had surgery, chemotherapy, or radiation and then developed problems like stiff shoulders, swelling, or tight scars. Researchers built a computer model to predict how long each person might need rehabilitation. The goal is to hel…

This study looked at whether a personalized follow-up schedule after breast cancer treatment is better than following standard guidelines. 261 women who finished initial treatment were randomly assigned to either a tailored plan or the usual schedule. The main goal was to see if …

This study looked at how itraconazole, an antifungal drug, changes the way the body processes HRS-8080, a medicine being developed for breast cancer. Sixteen healthy adults took HRS-8080 alone and then with itraconazole to measure drug levels and safety. The goal was to understan…

This study surveyed 109 men with prostate cancer and women with breast cancer to see how often they used complementary and alternative medicines (like supplements) during radiation therapy. Participants filled out surveys at three different times to track any changes in their use…

This study aimed to develop a questionnaire that measures quality of life specifically for men with breast cancer, since most existing tools focus on women. 65 men with breast cancer participated by rating which issues mattered most to them. The results will help create a validat…

This study measured how anthracycline-based chemotherapy affects blood pressure control and artery stiffness in 60 people with breast cancer or lymphoma. Researchers compared patients currently on chemo with those who finished treatment 1-5 years ago. The goal was to understand w…

This study looked at whether tiny molecules called microRNAs in the blood can help doctors know if hormone therapy will work for women with advanced breast cancer. Researchers tested blood samples from 39 women before and after one month of treatment with tamoxifen or an aromatas…

This study tested a noninvasive imaging method called DOSI that uses harmless near-infrared light to monitor how breast tumors respond to chemotherapy. Researchers scanned 24 women undergoing treatment to see if changes in oxygen levels in the tumor could predict whether the canc…

This study looked at how DNA from tumors changes in the blood before, during, and after surgery for breast, prostate, or colon cancer. Thirty adults having curative surgery provided blood samples to track these DNA levels. The goal was to gather basic information that could help …

This study tested whether an artificial intelligence (AI) model can accurately measure heart rhythm changes in breast cancer patients taking the drug ribociclib. The AI analyzed ECG data from 70 women and was compared to the standard method of measuring heart electrical activity.…

This study looked at whether giving doctors a free online risk score (PREDICT 2.1) changes how often they order an expensive gene test (Oncotype DX) for early-stage breast cancer. Over 600 patients took part. The goal was to see if the free tool could replace the costly test and …

This study analyzed health records from over 2 million people with type 2 diabetes to see if those taking the drug dapagliflozin had a different risk of developing breast or bladder cancer compared to those on other diabetes medications. Researchers followed participants for up t…

This study looked at how calcium and vitamin levels change in women receiving chemotherapy after breast cancer surgery. 146 patients were followed over 6 treatment cycles. The main goal was to see how often high calcium in urine occurs. This helps doctors better manage side effec…

This study examined how CDK4/6 inhibitors, a type of targeted therapy, are actually used in hospitals across Portugal for advanced or metastatic breast cancer. Researchers looked at data from 16 public hospitals involving nearly 2,000 patients to understand treatment patterns, ho…

This study looked at women aged 70 and older who finished early-stage breast cancer treatment within the past two months. Researchers used a geriatric assessment survey to find symptoms and issues, then shared results with the medical team to make referrals. The goal was to see i…

This study tested whether adding a drug that targets specific genetic changes found in some breast tumors could slow tumor growth more than standard hormone therapy alone. The trial included 19 people with ER-positive, HER2-negative breast cancer who received treatment before sur…

This study combined data from over 5,300 early-stage breast cancer patients to see how well dose-dense sequential chemotherapy works over the long term. Researchers looked at how long patients stayed cancer-free and overall survival, as well as side effects. The goal was to bette…

This study looked at 1,000 women who had breast reconstruction with implants right after mastectomy and also received radiation therapy. Researchers compared two types of implants—those with a polyurethan coating and those without—to see which had fewer problems like hardening (c…

This study looked at how physically active breast cancer patients in Spain are and what types of exercise they prefer. Researchers surveyed 507 patients to understand their activity levels and exercise likes. The goal is to use this information to create better exercise programs …

This study aimed to create a screening tool to identify women at high risk for long-term arm problems after breast cancer treatment. Researchers followed 1602 women who had surgery, chemotherapy, or radiation. The goal was to catch issues like pain, swelling, and limited movement…

This study looked at whether combining electronic health records with information provided directly by patients can lead to more accurate breast cancer risk predictions. Researchers worked with 70 women aged 35 to 74 who were at high risk for breast cancer. The goal was to improv…

This study looked for better ways to detect when breast cancer spreads to the lining of the brain and spinal cord. Researchers collected spinal fluid from 51 patients with suspected spread and compared a new test (CellSearch) to the standard method. The goal was to see if the new…

This study looked at how a breast cancer drug called SAR439859 is absorbed, broken down, and removed from the body. Six healthy postmenopausal women took a single dose of the drug with a tiny radioactive marker. Researchers measured the drug in blood, urine, and stool to understa…

This study looked at 480 patients with a common type of advanced breast cancer (HR+, HER2-) who were treated with a class of drugs called CDK4/6 inhibitors. Researchers wanted to understand patient characteristics, treatment patterns, and outcomes in everyday medical practice, no…

This study tested a method to identify immune cells (T cells) that recognize unique mutations in tumors from patients with breast cancer or melanoma. Researchers looked at lymph nodes invaded by cancer to see if these cells were present. The goal was to see if the method works, n…

This study looked at whether a mobile app teaching about HPV and breast cancer could improve women's understanding and attitudes toward screening. 70 women aged 30-65 used the app and completed surveys before and after. The goal was to see if the app increased HPV literacy and po…

This study looked at how a special tumor test, called the 21 gene Recurrence Score (OncotypeDx), affects whether doctors recommend chemotherapy for women with a common type of early-stage breast cancer. Researchers tracked 87 patients in Ireland to see if the test results changed…

This study looked at how the emotional skills of young women (45 or younger) with non-spreading breast cancer and their partners influence their ability to adjust to the disease. Researchers followed 391 couples through chemotherapy and beyond, measuring emotional abilities and w…

This study aimed to create a personalized 3D computer model of the breast to help surgeons better locate tumors and plan incisions during breast cancer surgery. Researchers measured skin elasticity and thickness in 200 women and performed additional MRI scans in 10 patients to un…

This study looked at whether a special PET scan (FDG-PET) can detect early if breast cancer is responding to chemotherapy, after just one cycle instead of waiting for three. Researchers scanned 63 women with breast tumors larger than 2 cm before and after their first chemo round.…