New strategy aims to stop opioids from causing more pain after breast surgery

NCT ID NCT03812003

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether giving a tiny amount of the opioid remifentanil right after surgery could prevent a condition called opioid-induced hyperalgesia, where opioids actually make pain worse. It involved 41 women with breast cancer having breast surgery under total intravenous anesthesia. The goal was to reduce pain and the need for extra painkillers after the operation.

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Conditions

The condition(s) this trial relates to.

breast cancer opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tri-Service General Hospital

    Taipei, 114, Taiwan