Small opioid dose after surgery may prevent pain rebound

NCT ID NCT03812003

First seen Feb 28, 2026 · Last updated May 12, 2026 · Updated 6 times

Summary

This study looked at whether giving a small amount of remifentanil right after breast surgery could prevent opioid-induced hyperalgesia—a condition where opioids actually make pain worse. 41 women with breast cancer having breast surgery under total intravenous anesthesia participated. The goal was to see if this approach could reduce pain scores and the need for extra painkillers in the recovery room.

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Contacts and locations

Locations

  • Tri-Service General Hospital

    Taipei, 114, Taiwan

Conditions

Explore the condition pages connected to this study.