Your own tumor cells could be the key to fighting cancer
NCT ID NCT05417750
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tested a personalized immunotherapy for people with advanced solid tumors. Doctors removed a sample of each patient's tumor, grew the immune cells (TILs) in a lab, and then infused them back along with another drug. The goal was to see if this approach is safe and can shrink tumors. The study included 43 patients with cancers like melanoma, cervical cancer, and lung cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tumor-infiltrating lymphocytes (TIL) plus sintilimab
- What this could lead to
- If successful, this could point toward a new immunotherapy option for people with advanced solid tumors like melanoma or cervical cancer.
- What could go wrong
- This is a very early phase 1 trial with only 43 participants, so safety and effectiveness are not yet proven. The treatment involves a complex process and may cause serious side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chinese PLA General Hospital
Beijing, Beijing Municipality, 100039, China
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