Hydrogel or spray? new study tests best way to soothe radiation skin damage

NCT ID NCT02839473

Completed Symptom relief Sponsor: Institut Curie Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested two skin treatments—a hydrogel dressing and a water spray—for women with breast cancer who developed skin irritation from radiotherapy. The goal was to see which one better prevented treatment delays or the need to switch care. 278 women with mild to moderate skin burns took part. The results could help improve comfort during cancer treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hydrogel Hydrosorb® (a moist wound dressing) and Castalie water spray
What this could lead to: If it works, this could provide a better way to manage skin irritation during radiotherapy, reducing treatment interruptions and improving comfort.
What could go wrong: This is a completed Phase 3 trial, but the results may show no significant benefit over a simple water spray. The intervention only addresses skin symptoms, not the cancer itself.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm radiodermatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER RADIATION DERMATITIS

Contacts and locations

Locations

Centre René Huguenin

Saint-Cloud, 92210, France
Institut Curie

Paris, 75005, France

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