New scan could spot breast cancer markers without a needle

NCT ID NCT05412446

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new imaging agent called 99mTc-ADAPT6 in 30 women with breast cancer that had spread to lymph nodes. The agent is designed to attach to HER2 proteins on cancer cells, allowing doctors to see them on a SPECT scan. The goal was to see if the scan results matched standard biopsy tests for HER2 status. If it works, this could offer a less invasive way to check HER2 levels in tumors and lymph nodes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Technetium-99m-labelled ADAPT6 (99mTc-ADAPT6)

What this could lead to

If successful, this imaging method could help doctors see HER2 levels in breast cancer without needing a biopsy, guiding treatment decisions.

What could go wrong

This is a small, early-phase study with only 30 participants, so results may not apply to all patients. The imaging agent may not match biopsy results perfectly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tomsk NRMC

    Tomsk, Russia