Ginseng extract studied for breast cancer effects

NCT ID NCT00631852

Completed Knowledge-focused Sponsor: Southern Illinois University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether an extract of American ginseng root (LEAG) could change certain markers in breast cancer tumors. Sixteen women took ginseng tablets for 5–14 days before their surgery. Researchers measured changes in inflammation and growth-related proteins in the tumor tissue. This was a very small, early-stage study focused on biological effects, not on treating or curing cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: American ginseng root extract (LEAG)
What this could lead to: If successful, this could point toward a natural supplement that might influence breast cancer biology, but it is not a treatment.
What could go wrong: This is a very small, early-phase study (16 people) looking at biomarkers, not survival or cure. Results may not lead to any clinical benefit.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Simmons Cancer Institute-SIU School of Medicine

Springfield, Illinois, 62702, United States

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