New imaging test may predict chemo success early in breast cancer
NCT ID NCT05402930
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a contrast-enhanced mammogram (angiomammography) can predict if breast cancer will fully disappear after chemotherapy. 67 women with breast cancer had imaging after two rounds of chemo. The goal was to see if this method could identify non-responders early, allowing doctors to switch treatments and improve outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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67 people
The number who actually took part.
- Started
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Jan 2018
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female aged 18 and over * Histologically proven breast cancer by large gauge needle * No evidence of distant metastasis * Neoadjuvant chemotherapy with or without concomitant targeted therapy * Breast tumor initially measurable by clinical examination Exclusion Criteria: * Refusal to perform the biopsy or surgery * Pregnant or possibly pregnant woman * Usual contraindication to contrast product * Significant kidney failure * Allergy to contrast medium * frank hyperthyroidism * Usual contraindications to MRI
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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St-Sacrement Hospital
Québec, Quebec, G1S4L8, Canada
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Other studies related to the condition(s) this trial covers.
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