Magnesium may boost pain relief after mastectomy

NCT ID NCT06815887

Completed Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding magnesium sulfate to a standard numbing medicine (bupivacaine) in a nerve block could improve pain control after a mastectomy. Seventy women having breast cancer surgery received either the standard nerve block or one with added magnesium. The goal was to see if the magnesium group needed less morphine and had less pain in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine and magnesium sulfate
What this could lead to: If it works, this could offer a simple, low-cost way to reduce pain and the need for strong painkillers after breast cancer surgery.
What could go wrong: This is a small, completed study with 70 participants. The results may not apply to all patients, and adding magnesium could cause side effects like low blood pressure or drowsiness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer local anesthetic poisoning Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCAL ANESTHETIC MAGNESIUM SULFATE MODIFIED RADICAL MASTECTOMY PECTORAL NERVE POSTOPERATIVE PAIN STELLATE GANGLION BLOCK

Contacts and locations

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Locations

Cairo University

Cairo, 12613, Egypt

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