New combo therapy shows promise in early breast cancer trial

NCT ID NCT05501769

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This early-phase trial tested a new drug, ARV-471, combined with everolimus in 32 people with advanced ER+/HER2- breast cancer that had stopped responding to other treatments. The main goals were to check safety and find the best dose. This is not a cure, but aims to better control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinical Trial Site

    San Diego, California, 92037, United States

  • Clinical Trial Site

    Santa Monica, California, 90404, United States

  • Clinical Trial Site

    Washington D.C., District of Columbia, 20007, United States

  • Clinical Trial Site

    Lake Mary, Florida, 32746, United States

  • Clinical Trial Site

    Ann Arbor, Michigan, 48109, United States

  • Clinical Trial Site

    Nashville, Tennessee, 37203, United States

  • Clinical Trial Site

    Barcelona, 08028, Spain

  • Clinical Trial Site

    Madrid, 28034, Spain

  • Clinical Trial Site

    Valencia, 46018, Spain

Conditions

Explore the condition pages connected to this study.