New hope for hard-to-treat breast cancer? early trial combines two targeted drugs
NCT ID NCT05501769
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tested a new combination of two drugs (ARV-471 and everolimus) in 32 people with a common type of advanced breast cancer (ER+/HER2-). The main goals were to find the safest dose and check for side effects. Researchers also looked at whether the tumors shrank or stayed stable. This study is for patients who have already tried other treatments, including CDK4/6 inhibitors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Trial Site
San Diego, California, 92037, United States
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Clinical Trial Site
Santa Monica, California, 90404, United States
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Clinical Trial Site
Washington D.C., District of Columbia, 20007, United States
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Clinical Trial Site
Lake Mary, Florida, 32746, United States
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Clinical Trial Site
Ann Arbor, Michigan, 48109, United States
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Clinical Trial Site
Nashville, Tennessee, 37203, United States
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Clinical Trial Site
Barcelona, 08028, Spain
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Clinical Trial Site
Madrid, 28034, Spain
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Clinical Trial Site
Valencia, 46018, Spain