Could a single injection replace biopsies for breast cancer?

NCT ID NCT05695859

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new imaging method that uses a radioactive tracer to detect HER2 protein in breast cancer tumors and nearby lymph nodes. 24 women with primary breast cancer received one injection followed by a scan. The goal was to see if the scan results matched standard tissue tests. If it works, this could offer a less invasive way to check HER2 status.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Technetium-99m-labelled DARPinG3

What this could lead to

If successful, this imaging method could help doctors see HER2 levels in breast cancer tumors without needing a biopsy, making diagnosis faster and less invasive.

What could go wrong

This is a small, early study with only 24 participants, so results may not apply to everyone. The imaging accuracy needs to be confirmed in larger trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm female breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Russia Tomsk NRMC

    Tomsk, Russia