Could a single injection replace biopsies for breast cancer?

NCT ID NCT05695859

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a new imaging method that uses a radioactive tracer to detect HER2 protein in breast cancer tumors and nearby lymph nodes. 24 women with primary breast cancer received one injection followed by a scan. The goal was to see if the scan results matched standard tissue tests. If it works, this could offer a less invasive way to check HER2 status.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Technetium-99m-labelled DARPinG3
What this could lead to
If successful, this imaging method could help doctors see HER2 levels in breast cancer tumors without needing a biopsy, making diagnosis faster and less invasive.
What could go wrong
This is a small, early study with only 24 participants, so results may not apply to everyone. The imaging accuracy needs to be confirmed in larger trials.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Russia Tomsk NRMC

    Tomsk, Russia

More trials for these conditions

Other studies related to the condition(s) this trial covers.