Single shot may stop chronic pain after breast surgery

NCT ID NCT06019325

Completed Symptom relief Sponsor: Muğla Sıtkı Koçman University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether a single injection of numbing medicine between the ribs (rhomboid intercostal block) can lower the chance of chronic pain after mastectomy. 254 women having breast cancer surgery were split into two groups: one got the block, the other did not. Researchers checked for pain at 3 and 6 months after surgery to see if the block made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine
What this could lead to: If effective, this simple nerve block could become a standard way to lower the chance of long-term pain after breast cancer surgery.
What could go wrong: This is a small, completed trial with no phase designation. The block only targets specific nerves, so it may not prevent all types of chronic pain. Results need confirmation in larger studies.

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia breast cancer breast neoplasm Chronic Pain neuralgia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER NEUROPATHIC PAIN POSTOPERATIVE PAIN, ACUTE POSTOPERATIVE PAIN, CHRONIC

Contacts and locations

Locations

Muğla Training and Research Hospital

Muğla, MENTEŞE, 48000, Turkey (Türkiye)

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