Radiation plus two immunotherapy drugs shows promise for tough cancers

NCT ID NCT02639026

First seen Jan 05, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This early-phase trial looked at combining a special type of radiation (hypofractionated radiotherapy) with two immunotherapy drugs (MEDI4736 and tremelimumab) for people with advanced melanoma, lung, breast, or pancreatic cancer that had spread. The main goal was to find the safest way to give this combination and to see how well patients tolerated it. 53 participants were enrolled to help determine the best dosing and side effects.

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Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.