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Nipple-Sparing mastectomy shows promise in breast cancer trial

NCT ID NCT02311959

Completed Disease control Sponsor: Institut Claudius Regaud Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a type of breast cancer surgery called nipple-sparing mastectomy, where the breast tissue is removed but the nipple and skin are kept. It involved 450 women with early-stage breast cancer who needed a full mastectomy. The goal was to see if this surgery keeps the cancer from coming back in the same area while improving appearance and quality of life.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast carcinoma in situ breast neoplasm in situ carcinoma invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

  • Ap-Hp - Hopital Tenon

    Paris, 75020, France

  • CHRU Lyon Sud

    Pierre-Bénite, 69495, France

  • Centre Antoine LACASSAGNE

    Nice, 06189, France

  • Centre Eugène Marquis

    Rennes, 35042, France

  • Centre Georges Francois Leclerc

    Dijon, 21079, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Centre Hospitalier Universitaire Grenoble Alpes

    La Tronche, 38700, France

  • Centre Hospitalier Universitaire de Montpellier

    Montpellier, 34295, France

  • Centre Hospitalier de Blois

    Blois, 41000, France

  • Centre Hospitalier de Poitiers

    Poitiers, 86 000, France

  • Centre Leon Berard

    Lyon, 69008, France

  • Centre Oscar Lambret

    Lille, 59000, France

  • Clinique Clementville

    Montpellier, 34070, France

  • Clinique Mathilde

    Rouen, 76175, France

  • Clinique Mutualiste Chirurgicale

    Saint-Etienne, 42013, France

  • Clinique Saint Amé

    Lambres-lez-Douai, 59552, France

  • Clinique Saint Jean

    Toulouse, 31077, France

  • Clinique du Mail

    La Rochelle, 17000, France

  • Etablissement Rennais du Sein - CHP St Grégoire

    Saint-Grégoire, 35760, France

  • Hopital de Levallois-Perret

    Levallois-Perret, 92300, France

  • Hôpital Européen Georges Pompidou, Assistance Publique - Hôpitaux de Paris

    Paris, 75015, France

  • Hôpital Privé de la Loire

    Saint-Etienne, 42100, France

  • Hôpital René Huguenin

    Saint-Cloud, 92210, France

  • Hôpital de la Croix Rousse

    Lyon, 69317, France

  • Hôpital privé Drôme Ardèche

    Guilherand-Granges, 07500, France

  • INSTITUT DE CANCEROLOGIE DE L'OUEST - Site René Gauducheau

    Saint-Herblain, 44805, France

  • Institut Bergonie

    Bordeaux, 33076, France

  • Institut Claudius Regaud

    Toulouse, 31059, France

  • Institut Du Cancer de Montpellier

    Montpellier, 34298, France

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

  • Institut de Cancerologie de Lorraine

    Vandœuvre-lès-Nancy, 54519, France

  • Pôle santé Léonard de Vinci

    Chambray-lès-Tours, 37170, France

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