Could less steroid before chemo be safer and just as effective?

NCT ID NCT02776436

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving a lower dose of the steroid dexamethasone before the chemotherapy drug docetaxel can prevent allergic reactions with fewer side effects. The standard high dose can cause problems like high blood sugar, mood changes, and weakened immunity. Researchers tested different lower doses in 46 people with breast or prostate cancer to find a safer option that still works.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Haga hospital

    The Hague, Netherlands

  • Leiden university medical center

    Leiden, Netherlands

  • Reinier de Graaf hospital

    Delft, Netherlands

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