New pill JAB-3312 tested in patients with advanced cancers
NCT ID NCT04045496
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested an oral drug called JAB-3312 in 40 adults with advanced solid tumors (like lung, colon, or breast cancer) that had stopped responding to standard treatments. The main goals were to find a safe dose and check for side effects. Researchers also looked for any signs that the drug might slow tumor growth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- JAB-3312 (an oral drug taken as capsules)
- What this could lead to
- If successful, this could lead to a new treatment option for people with advanced solid tumors who have run out of standard therapies.
- What could go wrong
- This is a very early Phase 1 trial with only 40 participants, so it is primarily testing safety and dosing. The drug may not shrink tumors or may cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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HealthONE Clinic Services Oncology-Hematology
Denver, Colorado, 80202, United States
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Tennessee Oncology, PLLC
Nashville, Tennessee, 37203, United States
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The University of Texas M. D. Anderson Cancer Center
Houston, Texas, 77030, United States
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Washington University School of Medicine
Seattle, Washington, 63110, United States
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