Triple drug attack on breast cancer shows promise

NCT ID NCT02520063

First seen Feb 06, 2026 · Last updated May 19, 2026 · Updated 12 times

Summary

This study tested a combination of three drugs (letrozole, everolimus, and TRC105) given before surgery to 15 postmenopausal women with hormone-receptor-positive, HER2-negative breast cancer. The goal was to see if the drugs were safe and could shrink tumors. The approach targets cancer cells, their growth signals, and the blood vessels feeding the tumor.

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Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

Conditions

Explore the condition pages connected to this study.