Japanese breast cancer survival data reviewed for palbociclib combo

NCT ID NCT04735367

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study in Japan reviewed medical records of 42 patients with HR+/HER2- advanced breast cancer who had been treated with palbociclib plus letrozole. The goal was to see how long patients lived after starting this treatment. It was a follow-up to an earlier phase 2 study and did not involve any new treatments or procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

palbociclib plus letrozole

What this could lead to

If successful, this study could confirm the real-world survival benefit of this drug combination for Japanese patients with advanced breast cancer.

What could go wrong

This is a small, retrospective observational study with only 42 patients, so results may not apply to broader populations. It does not test a new treatment, only reviews past data.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aichi Cancer Center

    Nagoya, 464-8681, Japan

  • Chiba cancer center

    Chiba, Chiba, 260-8717, Japan

  • Hakuaikai Medical Corporation Sagara Hospital

    Kagoshima, 892-0833, Japan

  • Hiroshima City Hiroshima Citizens Hospital

    Hiroshima, Hiroshima, 730-8518, Japan

  • Kumamoto Shinto General Hospital

    Kumamoto, 862-8655, Japan

  • Kumamoto University Hospital

    Kumamoto, Kumamoto, 860-8556, Japan

  • Kyoto University Hospital

    Kyoto, 606-8507, Japan

  • National Cancer Center Hospital

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Hospital Organization - Osaka National Hospital - Institute For Clinical Research

    Osaka, 540-0006, Japan

  • National Hospital Organization Hokkaido Cancer Center

    Sapporo, Hokkaido, 003-0804, Japan

  • National Hospital Organization Kyushu Cancer Center

    Fukuoka, 811-1395, Japan

  • National Hospital Organization Shikoku Cancer Center

    Matsuyama, Ehime, 791-0280, Japan

  • Saitama Cancer Center

    Kita-adachi-gun, Saitama, 362-0806, Japan