Real-World study confirms T-DM1 safety in advanced breast cancer

NCT ID NCT05945927

First seen Oct 31, 2025 · Last updated Apr 28, 2026 · Updated 25 times

Summary

This study observed 178 Chinese patients with HER2-positive advanced breast cancer who received the drug T-DM1 after earlier treatments failed. Researchers tracked side effects and how long the drug kept the cancer from growing in real-world settings. The goal was to confirm the drug's safety and effectiveness outside of controlled trials.

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Contacts and locations

Locations

  • Affiliated Hospital of Hebei University

    Baoding, China

  • Affiliated Hospital of Nantong University

    Nantong, 226001, China

  • Anhui Province Cancer Hospital

    Hefei, 230031, China

  • Anyang Tumor Hosptial

    Anyang, 455000, China

  • Beijing Hospital

    Beijing, 100730, China

  • Cancer Hospital Affliated to Xinjiang Medical University

    Ürümqi, 830011, China

  • Cancer Hospital Chinese Academy of Medical Sciences Shenzhen Center

    Shenzhen, 518127, China

  • Cancer Hospital Chinese Academy of Medical Sciences.

    Beijing, 100021, China

  • China Medical University (CMU) First Affiliated Hospital

    Shenyang, 110001, China

  • Dongyang People's Hospital

    Jinhua, China

  • First Affiliated Hospital of Medical College of Xi'an Jiaotong University

    Xi'an, 710061, China

  • Fujian Cancer Hospital

    Fuzhou, 350014, China

  • Guangxi Cancer Hospital of Guangxi Medical University

    Nanning, 530021, China

  • Harbin Medical University Cancer Hospital

    Harbin, 150081, China

  • Hubei Cancer Hospital

    Wuhan, 430079, China

  • Jiangmen Central Hospital

    Jiangmen, 529030, China

  • Nanjing Gulou Hospital

    Nanjing, China

  • Ningbo No.2 Hospital

    Ningbo, China

  • Shanxi Provincial Cancer Hospital

    Taiyuan, 030013, China

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, 510120, China

  • The Affiliated Cancer Hospital of Guizhou Medical University

    Guiyang, China

  • The First Affiliated Hospital Of Shandong First Medical University

    Jinan, 250014, China

  • The Third Hospital of Nanchang

    Nanchang, 330009, China

  • Tianjin Cancer Hospital

    Tianjin, China

  • Union Hospital of Tongji Medical College, Dept. of Cancer Center

    Wuhan, 430023, China

  • Weifang People's Hospital

    Weifang, 261041, China

  • West China Hospital of Sichuan University

    Chengdu, 610041, China

  • Yibin Second People's Hospital

    Yibin, China

  • Zhejiang Cancer Hospital

    Zhejiang, 310022, China

  • the First Hospital of Jilin University

    Changchun, 130021, China

Conditions

Explore the condition pages connected to this study.