New combo aims to stall breast cancer spread

NCT ID NCT01560416

First seen Mar 21, 2026 · Last updated Jun 13, 2026 · Updated 15 times

Summary

This study tested whether adding ganetespib, an experimental drug that blocks cancer cell growth, to the standard hormone therapy fulvestrant could better control metastatic breast cancer. Fifty adults with hormone receptor-positive, HER2-negative breast cancer that had spread and become resistant to hormone therapy took part. The main goal was to see if the combination delayed cancer progression compared to fulvestrant alone.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • DFCI at Faulkner Hospital

    Boston, Massachusetts, 02130, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • New Hampshire Oncology and Hematology, P.A.

    Concord, New Hampshire, 03301, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.