Indian breast cancer study tracks gene mutations and drug response

NCT ID NCT05022342

First seen Jan 02, 2026 · Last updated May 14, 2026 · Updated 18 times

Summary

This study was done in India to learn more about a gene change called PIK3CA in people with a specific type of advanced breast cancer (HR-positive, HER2-negative). It also looked at how well the drug alpelisib worked for those with the gene change. About 595 people took part, but no new treatments or tests were given—doctors made all decisions as usual. The goal was to gather information, not to test a new cure.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Hyderabad, Andhra Pradesh, 500034, India

  • Novartis Investigative Site

    Guwahati, Assam, 781023, India

  • Novartis Investigative Site

    Kochi, Kerala, 682041, India

  • Novartis Investigative Site

    Bhopal, Madhya Pradesh, 462001, India

  • Novartis Investigative Site

    Mumbai, Maharashtra, 400 012, India

  • Novartis Investigative Site

    Mumbai, Maharashtra, 400071, India

  • Novartis Investigative Site

    Nagpur, Maharashtra, 440001, India

  • Novartis Investigative Site

    Nagpur, Maharashtra, 441108, India

  • Novartis Investigative Site

    Pune, Maharashtra, 411004, India

  • Novartis Investigative Site

    New Delhi, National Capital Territory of Delhi, 110060, India

  • Novartis Investigative Site

    New Delhi, National Capital Territory of Delhi, 110092, India

  • Novartis Investigative Site

    Bhubaneswar, Odisha, 751003, India

  • Novartis Investigative Site

    Bhubaneswar, Odisha, 751007, India

  • Novartis Investigative Site

    Chandigarh, Punjab, 160055, India

  • Novartis Investigative Site

    Ludhiana, Punjab, 141008, India

  • Novartis Investigative Site

    Jaipur, Rajasthan, 302017, India

  • Novartis Investigative Site

    Sherilingampally, Telangana, 500019, India

  • Novartis Investigative Site

    Howrah, West Bengal, 711103, India

  • Novartis Investigative Site

    Kolkata, West Bengal, 700029, India

  • Novartis Investigative Site

    Kolkata, West Bengal, 700054, India

  • Novartis Investigative Site

    Kolkata, West Bengal, 700063, India

  • Novartis Investigative Site

    Ahmedabad, 380054, India

  • Novartis Investigative Site

    Kanpur, 208002, India

  • Novartis Investigative Site

    Kolkata, 700016, India

  • Novartis Investigative Site

    Kolkata, 700026, India

  • Novartis Investigative Site

    Kolkata, 700107, India

  • Novartis Investigative Site

    Puducherry, 605006, India

  • Novartis Investigative Site

    Udaipur, 313011, India

Conditions

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