New drug shows promise in shrinking breast cancer tumors before surgery

NCT ID NCT05659563

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called giredestrant against the standard drug tamoxifen in 92 premenopausal women with a common type of early breast cancer. Participants took the medication for 15 days before their planned surgery. The goal was to see how well each drug slowed tumor growth by measuring a marker called Ki67 in tissue samples taken before and after treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hopital Europeen Georges Pompidou

    Paris, Paris, France

  • Hospital Arnau de Vilanova de Valencia

    Valencia, Valencia, 46015, Spain

  • Hospital Beata Maria Ana

    Madrid, Madrid, Spain

  • Hospital Clinico Universitario de Valencia

    Valencia, Spain

  • Hospital Clínic i Provincial de Barcelona

    Barcelona, Barcelona, Spain

  • Hospital Clínico Universitario Virgen de la Arrixaca

    Murcia, Murcia, Spain

  • Hospital General Universitario Dr. Balmis

    Alicante, Alicante, 03010, Spain

  • Hospital Universitari Dexeus

    Barcelona, Barcelona, Spain

  • Hospital Universitari Sant Joan de Reus

    Reus, Tarragona, Spain

  • Hospital Universitario Clínico San Cecilio de Granada

    Granada, Granada, 18016, Spain

  • Hospital Universitario La Paz

    Madrid, Madrid, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, Madrid, Spain

  • Hospital Universitario Reina Sofía

    Córdoba, Cordoba, Spain

  • Hospital Universitario Virgen del Rocío

    Seville, Sevilla, 41013, Spain

  • Hospital Universitario de León

    León, Spain

  • Hôpital Tenon AP-HP

    Paris, France

  • Institut Català d' Oncologia Badalona

    Badalona, Barcelona, Spain

  • Instituto Valenciano de Oncología

    Valencia, Spain

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