New combo may ease chemo nausea for breast cancer patients

NCT ID NCT03367572

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 18 times

Summary

This study looked at whether adding prochlorperazine or olanzapine to standard anti-nausea medication can better control nausea and vomiting caused by chemotherapy in breast cancer patients. Over 1,300 women starting chemotherapy took part. The goal was to find a more effective way to manage these common and distressing side effects.

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Contacts and locations

Locations

  • Aurora NCORP

    Milwaukee, Wisconsin, 53226, United States

  • Cancer Research Consortium of West Michigan

    Grand Rapids, Michigan, 49503, United States

  • Cancer Research for the Ozarks NCORP

    Springfield, Missouri, 65804, United States

  • Columbus NCORP

    Columbus, Ohio, 43215, United States

  • Dayton Clinical Oncology Program

    Dayton, Ohio, 45459, United States

  • Decatur Memorial Hospital

    Decatur, Illinois, 62526, United States

  • Geisinger Cancer Institute NCORP

    Danville, Pennsylvania, 17822, United States

  • Greenville NCORP

    Greenville, South Carolina, 29615, United States

  • Gulf South MU-NCORP

    New Orleans, Louisiana, 70112, United States

  • Gundersen Health System

    La Crosse, Wisconsin, 54601, United States

  • Hawaii MU NCORP

    Honolulu, Hawaii, 96813, United States

  • Health Partners Inc

    Minneapolis, Minnesota, 55454, United States

  • Michigan Cancer Research Consortium

    Ann Arbor, Michigan, 48106, United States

  • Nevada Cancer Research Foundation NCORP

    Las Vegas, Nevada, 89106, United States

  • Saint Vincent Hospital Cancer Center Green Bay

    Green Bay, Wisconsin, 54301, United States

  • Southeast Clinical Oncology Research Program

    Winston-Salem, North Carolina, 27104, United States

  • University of Rochester NCORP Research Base

    Rochester, New York, 14642, United States

  • Upstate Carolina NCORP

    Spartanburg, South Carolina, 29303, United States

Conditions

Explore the condition pages connected to this study.