Promising drug targets breast cancer in the brain
NCT ID NCT01494662
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called neratinib, alone or with other medicines, in 140 people with HER2-positive breast cancer that spread to the brain. The goal was to see if the drug could shrink or stabilize brain tumors. Results help doctors understand how well this treatment works for this hard-to-treat condition.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Arnold Palmer Cancer Center-Greensburg
Greensburg, Pennsylvania, 15601, United States
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Baylor College of Medicine Lester and Sue Smith Breast Center
Houston, Texas, 77030, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Massachusetts General Hosptial
Boston, Massachusetts, 02215, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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MedStar Georgetown Univeristy Hospital
Washington D.C., District of Columbia, 20007, United States
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, 21231, United States
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UPMC Cancer Centers - Magee-Womens Hospital of UPMC
Pittsburgh, Pennsylvania, 15213, United States
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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UPMC Ortenzio Cancer Center
Mechanicsburg, Pennsylvania, 17050, United States
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UPMC Passavant Cranberry
Cranberry Township, Pennsylvania, 16066, United States
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UPMC Pinnacle Harrisburg
Harrisburg, Pennsylvania, 17101, United States
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University of California, San Francisco Medical Center
San Francisco, California, 94115, United States
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University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of North Carolina at Chapel Hill - Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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