Promising drug targets breast cancer in the brain
NCT ID NCT01494662
First seen Jan 25, 2026 · Last updated Jun 14, 2026 · Updated 23 times
Summary
This study tested a drug called neratinib, alone or with other medicines, in 140 people with HER2-positive breast cancer that spread to the brain. The goal was to see if the drug could shrink or stabilize brain tumors. Results help doctors understand how well this treatment works for this hard-to-treat condition.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Arnold Palmer Cancer Center-Greensburg
Greensburg, Pennsylvania, 15601, United States
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Baylor College of Medicine Lester and Sue Smith Breast Center
Houston, Texas, 77030, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Massachusetts General Hosptial
Boston, Massachusetts, 02215, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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MedStar Georgetown Univeristy Hospital
Washington D.C., District of Columbia, 20007, United States
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, 21231, United States
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UPMC Cancer Centers - Magee-Womens Hospital of UPMC
Pittsburgh, Pennsylvania, 15213, United States
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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UPMC Ortenzio Cancer Center
Mechanicsburg, Pennsylvania, 17050, United States
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UPMC Passavant Cranberry
Cranberry Township, Pennsylvania, 16066, United States
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UPMC Pinnacle Harrisburg
Harrisburg, Pennsylvania, 17101, United States
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University of California, San Francisco Medical Center
San Francisco, California, 94115, United States
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University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of North Carolina at Chapel Hill - Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
Conditions
Explore the condition pages connected to this study.