Immunotherapy combo shows promise against stubborn breast cancer

NCT ID NCT03095352

First seen Jan 08, 2026 · Last updated May 14, 2026 · Updated 19 times

Summary

This study tested whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (carboplatin) helps control breast cancer that has returned on the chest wall. 76 women with hormone-resistant or triple-negative breast cancer took part. The goal was to see if the combination shrinks tumors or stops them from growing longer than chemo alone.

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Contacts and locations

Locations

  • Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Indiana University/Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

  • University of Pittsburgh Cancer Institute

    Pittsburgh, Pennsylvania, 15232, United States

  • Vanderbilt University/Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.