Scientists test new way to spot Cancer-Fighting immune cells in lymph nodes

NCT ID NCT02831634

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 29 times

Summary

This study tested a method to identify tumor mutations and measure immune cell responses in the lymph nodes of 25 patients with breast cancer or melanoma. Researchers took blood samples and used two techniques to find which mutations trigger T-cell activity. The goal was to see if this approach is feasible for future personalized cancer treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Institut Curie

    Paris, 75005, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this method could help develop personalized cancer vaccines or immunotherapies by identifying which tumor mutations trigger an immune response.

What could go wrong

This is a very early feasibility study with only 25 participants. The method may not work in all patients or may be too complex for routine use.

Conditions

The condition(s) this trial relates to.

breast neoplasm melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.