Scientists probe hidden tumor changes to outsmart drug resistance in breast cancer

NCT ID NCT00897702

First seen Jan 29, 2026 · Last updated May 23, 2026 · Updated 17 times

Summary

This study looked at why some breast cancer treatments stop working over time. Researchers took tumor samples from 269 patients whose cancer had returned or worsened after targeted therapy. By studying genetic and protein changes in the tumors, they hope to understand resistance and develop better treatments in the future.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (Consent only)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Consent only)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack (Consent only)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (Consent only)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Consent only)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (Consent only)

    Harrison, New York, United States

Conditions

Explore the condition pages connected to this study.