New drug FS1502 targets Hard-to-Treat HER2 cancers in early trial

NCT ID NCT03944499

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-phase trial tested an experimental drug called FS1502 in 161 people with advanced solid tumors or breast cancer that express HER2. The study had two parts: first, finding a safe dose, and then seeing how well that dose works. The goal was to check safety and early signs of tumor shrinkage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FS-1502 (an experimental drug given by IV)

What this could lead to

If it works, this could point toward a new treatment option for people with HER2-positive advanced solid tumors or breast cancer.

What could go wrong

This is a very early Phase 1 trial with only 161 participants, so safety and dosing are still being figured out. It may not show strong anti-tumor effects or lead to a widely available therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

    Beijing, Beijing Municipality, 100021, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, China

  • Jilin Cancer Hospital

    Jilin City, Changchun, China

  • Meizhou People's Hospital

    Meizhou, Guangdong, China

  • Run Run Shaw Hospital Affiliated to Medical College of Zhejiang University

    Hangzhou, Zhejiang, 310016, China

  • Shandong Cancer Hospital

    Jinan, Shandong, China

  • Shenzhen Hospital, Cancer Hospital, Chinese Academy of Medical Sciences

    Shenzhen, Guangdong, 518000, China

  • Sun Yat-sen University Cancer Prevention Center

    Guangzhou, Guangdong, China

  • The First Affiliated Hospital of Bengbu Medical College

    Bengbu, Anhui, China

  • The Fourth Hospital of Hebei Medical University

    Shijiazhuang, Hebei, 050011, China

  • Tianjin Cancer Hospital

    Tianjin, Tianjin Municipality, China

  • Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, China