New combo shot may cut morphine use after breast cancer surgery
NCT ID NCT03063073
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding dexmedetomidine (a sedative) to a standard numbing medicine (bupivacaine) in a chest nerve block could improve pain control after breast cancer surgery. Sixty women received either the standard block or the block with added dexmedetomidine. The main goal was to see if the combination reduced the amount of morphine needed for pain in the first two days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine (Precedex) added to bupivacaine (Marcaine)
What this could lead to
If it works, this could offer better pain control and less need for morphine after breast cancer surgery.
What could go wrong
This is a small, completed Phase 3 trial with only 60 participants, so results may not apply to everyone. Adding drugs to nerve blocks can sometimes cause side effects like low blood pressure or slow heart rate.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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South EGYPT cancer institute
Asyut, 088, Egypt