Could a Pre-Surgery pill cut morphine use after breast cancer surgery?

NCT ID NCT07320781

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether giving the painkiller tapentadol before breast cancer surgery could lower the amount of morphine needed during and right after the operation. Seventy patients took either tapentadol or a placebo one hour before surgery. Researchers measured morphine use and pain scores for up to four hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tapentadol

What this could lead to

If it works, this could offer a way to manage pain after breast cancer surgery with less reliance on strong opioids like morphine.

What could go wrong

This is a small, completed study with only 70 participants. The results may not apply to everyone, and tapentadol can cause side effects like nausea or dizziness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • SKMCH & RC Lahore

    Lahore, Punjab Province, 042, Pakistan