Internal radiation therapy shows promise in pilot study for multiple cancers

NCT ID NCT00924027

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This pilot study tested high dose rate brachytherapy, a type of internal radiation, in 43 patients with cervical, endometrial, esophageal, prostate, or biliary cancer. The goal was to see if the radiation implants could deliver the planned dose accurately. Participants received brachytherapy as part of their treatment and were followed for up to a year. The study focused on implant quality and local tumor control.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
High Dose Rate Brachytherapy (internal radiation)
What this could lead to
If successful, this could help refine brachytherapy techniques to better target tumors while sparing healthy tissue, potentially improving cancer control.
What could go wrong
This is a small, early-phase pilot study (43 participants) focused on procedure quality, not survival. Results may not apply to all patients or cancer types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.