Internal radiation therapy shows promise in pilot study for multiple cancers

NCT ID NCT00924027

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested high dose rate brachytherapy, a type of internal radiation, in 43 patients with cervical, endometrial, esophageal, prostate, or biliary cancer. The goal was to see if the radiation implants could deliver the planned dose accurately. Participants received brachytherapy as part of their treatment and were followed for up to a year. The study focused on implant quality and local tumor control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High Dose Rate Brachytherapy (internal radiation)

What this could lead to

If successful, this could help refine brachytherapy techniques to better target tumors while sparing healthy tissue, potentially improving cancer control.

What could go wrong

This is a small, early-phase pilot study (43 participants) focused on procedure quality, not survival. Results may not apply to all patients or cancer types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms breast cancer cervical cancer endometrial cancer endometrium neoplasm esophageal cancer Esophageal Neoplasms lung cancer neoplasm prostate cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States