Chemo's hidden toll on blood vessels revealed

NCT ID NCT04042298

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study measured blood flow in the skin of 62 people, including cancer patients who received 5-FU chemotherapy, those on other treatments, cancer survivors, and healthy controls. Researchers used a non-invasive laser sensor to see how small blood vessels responded to substances that widen or narrow them. The goal was to understand why 5-FU can cause heart problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help explain how 5-FU chemotherapy affects blood vessels, potentially leading to better monitoring or prevention of heart-related side effects.

What could go wrong

This is a small, completed observational study that only measures blood flow at one time point. It does not test any treatment, so it cannot directly improve patient care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

5-fluorouracil toxicity breast cancer breast neoplasm chemotherapy-induced toxicity digestive system cancer digestive system neoplasm head and neck cancer Head and Neck Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Lafene Health Center

    Manhattan, Kansas, 66502, United States