Study hints at less surgery for certain breast cancers

NCT ID NCT07211451

Completed Knowledge-focused Sponsor: Gangnam Severance Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at over 1,500 women with early-stage HER2-positive or triple-negative breast cancer who had no signs of cancer in their lymph nodes on ultrasound. All had breast-conserving surgery with lymph node removal. The goal was to see how often cancer actually spread to the nodes, and whether some patients could safely skip the lymph node biopsy in the future. The findings could lead to less invasive surgery for selected patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help some breast cancer patients avoid unnecessary lymph node surgery, reducing side effects like arm swelling.
What could go wrong: This is an observational analysis of past data, not a clinical trial testing a new treatment. The findings need confirmation in future studies before changing practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Gangnam Severance Hospital, Yonsei University College of Medicine

Seoul, Please Select, 06273, South Korea

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Other studies related to the condition(s) this trial covers.