Can surgery or frequent blood tests stop ovarian cancer in High-Risk women?

NCT ID NCT00043472

First seen Oct 31, 2025 · Last updated May 08, 2026 · Updated 28 times

Summary

This study looked at two ways to manage ovarian cancer risk in 40 women with BRCA gene mutations or strong family history. One group had preventive surgery to remove ovaries and fallopian tubes, while the other group had regular CA-125 blood tests to catch cancer early. Researchers tracked cancer rates, tissue changes, and quality of life to see which approach works best.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.