Mastectomy pain study: which drug works best?

NCT ID NCT06974656

Completed Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested two drugs, dexmedetomidine and lidocaine, given during surgery to control pain after a mastectomy. 40 women took part. The goal was to see which drug delays the need for extra pain medicine and keeps vital signs stable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dexmedetomidine and lidocaine

What this could lead to

If one drug works better, it could offer a more effective way to control pain right after mastectomy, reducing the need for stronger painkillers.

What could go wrong

This is a small, early-stage trial with only 40 people, so results may not apply to everyone. Both drugs have known side effects like low blood pressure or heart rate changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute disease breast cancer Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE DEXMEDETOMIDINE INFUSION LIDOCAINE MODIFIED RADICAL MASTECTOMY POSTOPERATIVE PAIN

Contacts and locations

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Locations

Cairo University

Cairo, 12613, Egypt