A protein from tumors may show up in blood — a trial puts the idea to the test

NCT ID NCT06068257

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This study investigates whether a protein called FGF19, normally found in the intestine and gallbladder, appears at higher levels in the blood of people with breast or colorectal cancer compared to healthy individuals. Researchers will measure FGF19 and related markers in fasting blood samples from about 119 adults — including cancer patients and healthy controls — to see if it could serve as a cancer detection biomarker. The goal is to establish whether tumors actively release FGF19 into the bloodstream and whether blood levels can distinguish people with cancer from those without.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
blood test for FGF19 protein levels
What this could lead to
If successful, this could lead to a simple blood test to help detect breast or colorectal cancer earlier.
What could go wrong
This is an early-stage study to establish whether FGF19 levels differ between groups. It may not prove useful as a reliable screening tool, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Burnett School Biomedical Sciences

    Orlando, Florida, 32816, United States

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