Smart drug delivers chemo directly to HER2 breast cancer cells

NCT ID NCT06115902

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests an experimental drug called TQB2102 for people with HER2-positive breast cancer that has returned or spread to other parts of the body. TQB2102 is an antibody-drug conjugate—a targeted therapy that binds to HER2 on cancer cells and releases a potent chemotherapy directly inside them. The study aims to see if the drug can shrink tumors and how safe it is. Participants must have HER2-expressing breast cancer that is not curable with surgery or radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
TQB2102 (antibody-drug conjugate targeting HER2)
What this could lead to
If successful, TQB2102 could offer a new treatment option for people with HER2-positive breast cancer that has returned or spread.
What could go wrong
This is an early-phase trial, so the drug may not shrink tumors or may cause side effects. It is too soon to know if it will be better than existing therapies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Anhui Pronvincial Cancer Hospital

    Hefei, Anhui, 230000, China

  • Cancer Hospital Affiliated to Shandong First Medical University

    Jinan, Shandong, 250117, China

  • Cancer Hospital Chinese Academy of Medical Science

    Beijing, Beijing Municipality, 100021, China

  • Chongqing University Cancer Hospital

    Chongqing, Chongqing Municipality, 400030, China

  • Ganzhou People's Hospital

    Ganzhou, Jiangxi, 341000, China

  • Guangxi Medical University Cancer Hospital

    Nanning, Guangxi, 530021, China

  • Harbin Medical University Cancer Hospital

    Harbin, Heilongjiang, 150081, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410031, China

  • Jiangmen Central Hospital

    Jiangmen, Guangdong, 529000, China

  • Jilin Cancer Hospital

    Changchun, Jilin, 130012, China

  • Liaoning Cancer Hospital & Institute

    Shenyang, Liaoning, 110000, China

  • Linyi Cancer Hospital

    Linyi, Shandong, 276034, China

  • Lu'an People's Hospital

    Lu'an, Anhui, 237008, China

  • Shanxi Cancer Hospital

    Taiyuan, Shanxi, 030000, China

  • Suining Central Hospital

    Suining, Sichuan, 629000, China

  • Sun Yat-Sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • The First Affiliated Hospital of Xi'an Jiaotong University School of Medicine

    Xi'an, Shannxi, 710089, China

  • The First Hospital of China Medical University

    Shenyang, Liaoning, 110001, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjin, Tianjin Municipality, 300202, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

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