New drug combo shows promise against aggressive breast cancer

NCT ID NCT01796197

First seen Feb 05, 2026 · Last updated May 12, 2026 · Updated 13 times

Summary

This study tested a three-drug combination (paclitaxel, trastuzumab, and pertuzumab) given before surgery to 23 people with a rare and aggressive type of breast cancer called inflammatory breast cancer. The goal was to see if the treatment could eliminate all signs of cancer in the breast and lymph nodes at the time of surgery. Participants also continued two of the drugs for a full year after surgery to help prevent the cancer from coming back.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.