Light-Based imaging may predict chemo success in breast cancer

NCT ID NCT02510456

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a noninvasive imaging method called Diffuse Optical Spectroscopy Imaging (DOSI) to see if it could predict how breast cancer responds to chemotherapy. Twenty-four women with breast cancer were scanned up to 9 times during their treatment. The goal was to see if changes in oxygen levels in the tumor could forecast whether the cancer would completely disappear after chemo.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this imaging technique could help doctors quickly see if chemotherapy is working, potentially guiding treatment adjustments without extra biopsies.
What could go wrong
This was a small, early study with only 24 participants. The imaging method is still experimental and may not reliably predict response in all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States

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Other studies related to the condition(s) this trial covers.